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Biological medicine wound dressing

A biomedicine and wound technology, applied in dressings, medical science, viscous dressings, etc., can solve the problems of ineffective release of medicinal ingredients, poor anti-inflammatory and disinfection effects, and unfavorable wound air permeability, so as to facilitate wound healing and effective Conducive to the protection of the environment and the effect of reducing the formation of scars

Active Publication Date: 2020-08-04
欣乐加生物科技温州有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Most of the existing wound dressings or wound bandages do not contain medicinal ingredients, or the medicinal ingredients are contained in water-absorbing materials. Dressings without medicinal ingredients can only prevent external dust and bacterial infection, and cannot effectively sterilize the wound. ; The dressing containing the medicinal ingredients in the water-absorbing material cannot effectively release the medicinal ingredients to the wound. Only when the wound and the dressing are closely attached can the medicine contained in the dressing on the wound joint be applied to the wound. In addition, the medicinal ingredients contained in the dressing cannot be effectively applied to the wound, and the drugs in the dressing cannot be fully utilized. The anti-inflammatory and disinfection effects are poor, and some wound locations cannot make the dressing fit tightly to the wound. On the wound, at this time, the medicine contained in the dressing cannot act on the wound, and the medicine in the dressing cannot be fully utilized, and the anti-inflammatory and disinfection effects are also poor, resulting in waste of medicine, and even if the dressing can fit the wound tightly It is also not conducive to the air permeability of the wound and affects the healing of the wound.

Method used

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  • Biological medicine wound dressing
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The hydrophilic film drug layer is prepared by the following mass content ratio:

[0044] Chitosan content 10%, sulfamethoxazole content 1%, dexamethasone content 1%, borneol content 0.5%, safflower content 2%, trimethoprim content 1%, rifamycin content 1%, peppermint Brain 1%, Clindamycin Hydrochloride 13%, Nano Silver Particles 1%, Carboxyvinyl Polymer and / or Hydroxypropyl Methyl Cellulose 10%, Trehalose 1%, Carotenoids 1%, the solution prepared after the reaction, the solution is drip-coated on the polylactic acid layer, and dried to obtain a hydrophilic film drug layer;

[0045] Paste the dried polylactic acid receiving layer carrying the hydrophilic film drug layer on the water-absorbing layer, paste the water-absorbing layer on the base layer, and stick the adhesive layer on the edge of the base layer and the edge of the water-absorbing layer In between, prepare the dressing.

Embodiment 2

[0047] The hydrophilic film drug layer is prepared by the following mass content ratio:

[0048] Chitosan content 15%, sulfamethoxazole content 5%, dexamethasone content 5%, borneol content 2%, safflower content 3.5%, trimethoprim content 3%, rifamycin content 2.5%, mint content Brain content 2%, clindamycin hydrochloride content 3%, nano silver particle content 8%, carboxyvinyl polymer and / or hydroxypropyl methylcellulose content 35%, trehalose content 5%, carotenoid content 5%, the solution prepared after the reaction, the solution is drip-coated on the polylactic acid layer, and dried to obtain a hydrophilic film drug layer;

[0049] Paste the dried polylactic acid receiving layer carrying the hydrophilic film drug layer on the water-absorbing layer, paste the water-absorbing layer on the base layer, and stick the adhesive layer on the edge of the base layer and the edge of the water-absorbing layer In between, prepare the dressing.

Embodiment 3

[0051] The hydrophilic film drug layer is prepared by the following mass content ratio:

[0052] Chitosan content 13%, sulfamethoxazole content 3%, dexamethasone content 3%, borneol content 1.5%, safflower content 3%, trimethoprim content 2%, rifamycin content 1.5%, mint content Brain content 1.5%, clindamycin hydrochloride content 1.5%, nano silver particle content 4%, carboxyvinyl polymer and / or hydroxypropyl methylcellulose content 13%, trehalose content 3%, carotenoid content 3%, the solution prepared after the reaction, the solution is drip-coated on the polylactic acid layer, and dried to obtain a hydrophilic film drug layer;

[0053] Paste the dried polylactic acid receiving layer carrying the hydrophilic film drug layer on the water-absorbing layer, paste the water-absorbing layer on the base layer, and stick the adhesive layer on the edge of the base layer and the edge of the water-absorbing layer In between, prepare the dressing.

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Abstract

The invention provides a biological medicine wound dressing. The biological medicine wound dressing comprises a first component, a second component and a third component, the patch comprises a substrate layer, a water absorption layer, a medicine layer, a bearing layer and an adhesive layer, the medicine layer is a medicine-containing hydrophilic film; wherein the water absorption layer is fixed on the substrate layer; wherein the bearing layer is fixed on the water absorption layer, the medicine layer is fixed on the bearing layer, the hydrophilic film medicine layer can be dissolved by contacting with liquid flowing out of a wound, the dissolved medicine acts on the wound, the effects of diminishing inflammation and killing bacteria can be effectively achieved, the medicine in the dressing can be fully utilized, and the wound treatment effect can be improved.

Description

technical field [0001] The invention belongs to the technical field of biomedical dressings, in particular to a biomedical wound dressing. Background technique [0002] Uncontrollable wound infection can also endanger life safety. In addition to massive bleeding during wound healing, chronic inflammation is an important factor hindering wound healing. For wound infection, that is, chronic inflammation caused by a large number of bacteria colonizing the wound. [0003] Most of the existing wound dressings or wound bandages do not contain medicinal ingredients, or the medicinal ingredients are contained in water-absorbing materials. Dressings without medicinal ingredients can only prevent external dust and bacterial infection, and cannot effectively sterilize the wound. ; The dressing containing the medicinal ingredients in the water-absorbing material cannot effectively release the medicinal ingredients to the wound. Only when the wound and the dressing are closely attached ...

Claims

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Application Information

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IPC IPC(8): A61L15/46A61L15/42A61L15/26A61F13/02
CPCA61L15/46A61L15/42A61L15/26A61F13/0203A61F13/00063A61L2300/404A61L2300/41A61L2300/412A61L2300/45C08L67/04
Inventor 卢丽菊
Owner 欣乐加生物科技温州有限公司
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