A polymer cleaning drilling fluid system, which is made of the following raw materials: tap water, bentonite, sodium carbonate, sodium hydroxide, fluid loss reducer, wall solidifying agent, coating agent, polyanionic cellulose, high temperature resistant Salt fluid loss reducer, lubrication inhibitor, solid lubricant for drilling fluid, solid lubricant graphite, KCl, gel plugging agent, ultrafine calcium carbonate powder, weighting agent barite powder. The preparation method of the fluid loss reducer and the wall-fixing agent is also provided. FL after aging at 180°C in the present invention HTHP ≤13mL, 8h linear expansion reduction rate ≥80%, cuttings rolling recovery rate ≥92%, mud cake adhesion coefficient ≤0.1, it has good fluid loss control performance, inhibition performance and lubricating performance, suitable for sand-shale mixed layer Drilling of deviated or horizontal sections of formations. The invention has good comprehensive performance, low cost, environmental protection, effectively solves the problem of well wall instability easily caused by water-based drilling fluid in the drilling process, and is beneficial to wellbore cleaning, reservoir cleaning and environmental protection.