The invention discloses a novel
dosage form containing
albendazole and application and a preparation method thereof. The novel
dosage form mainly takes the mixture of
albendazole and pamoic acid pyrantel as a medicinal composition, and an
excipient and a flavoring agent are added to the medicinal composition to be made into granules. The novel
dosage form contains 500-800 parts of medicinal composition, 40-120 parts of
excipient and 50-100 parts of flavoring agent in parts by weight. The granules have the advantages of good
drug disperse states, short disintegration time, rapid
drug dissolution, rapid absorption, high
bioavailability and the like and are convenient to take. The
drug mouthfeel can be regulated according to the fondness of children, such as the apple taste, the lemon taste and the like. The novel dosage form is especially suitable for children, patients with special conditions and patients who are difficult to swallow. However, the children are
parasitic disease susceptible populations but have poorer
drug compliance. In order to increase the
drug compliance of the children and improve the drug
mouthfeel and the taking mode, designing the dosage form into the granules is extremely necessary. The invention also makes the orally taken dosage form of the compound
albendazole granules diversified and simultaneously provides more selections for clinician and patient medications.