46 results about "Plasmonic nanoparticles" patented technology

A sensor for determining the presence or concentration of a target entity in a medium is described, and includes (a) an optical waveguide; (b) a microresonator optically coupled with the optical waveguide such that light within the optical waveguide induces a resonant mode within the microresonator at an equator region (or a mode volume); and (c) at least one plasmonic nanoparticle adsorbed onto a surface area of the microresonator within the equator region (or the mode volume) such that light inducing a resonant mode within the microresonator also causes a plasmonic resonance in the at least one plasmonic nanoparticle. Detection methods for using such sensors are also described. Finally, methods, involving the use of carousel forces, for fabricating such sensors are also described.

Enhanced delivery of compositions for treatment of skin tissue with photoactive plasmonic nanoparticles and light, with embodiments relating to delivery devices using, for example, ultrasound. Treatments are useful for cosmetic, diagnostic and therapeutic applications.

A surface enhanced Raman spectroscopy (SERS) analytical device includes a substrate having a porous structure, and a plurality of plasmonic nanoparticles embedding in the porous structure and forming a sensing region. A method of detecting a target analyte in a sample includes contacting the sample with the substrate, whereby the target analyte, if present in the sample, is concentrated in the sensing matrix. The substrate may then be analyzed using SERS detection equipment.

A method for accurately detecting temperature based on surface-enhanced Raman scattering effect, comprising the following steps: (1) loading a plasmonic nanoparticle monolayer film on a support substrate; (2) soaking the monolayer film substrate in a probe In the molecular solution, it is dried to make a hard substrate temperature sensor or a flexible substrate temperature sensor; (3) The hard substrate temperature sensor or flexible substrate temperature sensor is placed under a gradient working temperature to collect the Raman spectrum of its surface, and the characteristic temperature is established. and the standard curve between the corresponding characteristic peak intensity; (4) place the hard substrate temperature sensor or flexible substrate temperature sensor in the detection range, collect the Raman spectrum of its surface, read the characteristic peak intensity and the temperature The standard curve comparison of the interval can realize the detection of unknown ambient temperature. The invention is simple to operate, and can realize reproducible, high-stability and high-precision temperature detection based on the temperature-dependent SERS effect of the plasmonic nanoparticle monolayer film.

The present disclosure relates to luminescent including photon up-conversion nanoparticles. These nanoparticles include a polymeric organic matrix, at least one light emitter distributed within this matrix, a stabilizing agent, and at least one metal particle enclosed within the matrix, wherein the metal particles are plasmonic nanoparticles. The present disclosure further relates to methods of manufacture and to uses of such nanoparticles.

The invention provides a nanoantenna scanning probe tip for microscropy or spectroscopy. The nanoantenna scanning probe tip includes a sharp probe tip covered with a contiguous film of predetermined sized and shaped plasmonic nanoparticles. A method for forming the nanoantenna scanning probe tip by trapping nanoparticles having a predetermined size and shape at a liquid surface using surface tension, forming a uniform and organized monolayer film on the liquid surface, and then transferring portions of the film to a sharp probe tip. In preferred embodiments, the sharp probe tip is one of a conductive STM (scanning tunneling microscopy) tip, a tuning fork tip or an AFM (atomic force microscopy) tip. The sharp tip can be blunted with an oxide layer.

Disclosed herein are nanoparticle-based plasmonic solutions to therapeutic applications employing titanium nitride (TiN) and other non-stoichiometric compounds as the plasmonic material. Current solutions are suboptimal because they require complex shapes, large particle sizes, and a narrow range of sizes, in order to achieve plasmonic resonances in the biological window. The nanoparticles discloses herein provide plasmonic resonances occurring in the biological window even with small sizes, simple shapes, and better size dispersion restrictions. Local heating efficiencies of such nanoparticles outperform currently used Au and transition metal nanoparticles. The use of smaller particles with simpler shapes and better heating efficiencies allows better diffusion properties into tumor regions, larger penetration depth of light into the biological tissue, and the ability to use excitation light of less power.

A method for characterizing extracellular vesicles at an individual level is described. It comprises obtaining a sample comprising extracellular vesicles to be characterized and functionalizing the extracellular vesicles with plasmonic nanoparticles or a plasmonic coating. The method further comprises irradiating the individual extracellular vesicles with a laser beam and detecting a surface enhanced Raman spectroscopy signal from said individual extracellular vesicle.

The invention relates to an exciton-plasma coupling system, its construction method and a method for enhancing the generation of singlet oxygen of a photosensitizer by utilizing the coupling system. The exciton-plasmon coupling system of the present invention is a core-shell structure formed by the adsorption of photosensitizer excitons and plasmonic nanoparticles, and the LSPR absorption peak of the plasmonic nanoparticles covers the excitation of the photosensitizer in the visible region. sub-absorption peaks. The method of the invention includes selecting the peak position and concentration of the plasmonic nanoparticle, the type and concentration of the charged substance, and the peak position and concentration of the photosensitizer to form a stable coupling system. Measure the singlet oxygen yield of the product by electron spin resonance technology, and determine that the coupling effect is the main factor for enhancing the singlet oxygen yield of the photosensitizer through the measurement of Raman spectroscopy. The results show that the exciton-plasmon coupling of the present invention The system has a higher singlet oxygen yield than the uncoupled system.