The object of the invention is to provide a composition for prevention and / or amelioration of life-style related
disease, and / or a composition for inhibition and / or amelioration of increase in
body weight, comprising at least one compound selected from the group consisting of glabrene,
glabridin, glabrol, 3′-hydroxy-4′-O-methylglabridin, 4′-O-methylglabridin and hyspaglabridin B as compounds having a PPAR ligand activity effective in amelioration of
insulin resistance and in prevention and / or amelioration of life-style related diseases such as
visceral fat obesity, type 2 diabetes, hyperlipemia and hypertension, which can be utilized in food and drink such as
health food and health
functional food (food for specified uses and food with
nutrient function), pharmaceutical preparations, non-pharmaceutical preparations,
cosmetics etc. At least one compound selected from the group consisting of glabrene,
glabridin, glabrol, 3′-hydroxy-4′-O-methylglabridin, 4′-O-methylglabridin and hyspaglabridin B is dissolved in medium-chain
fatty acid triglycerides and / or partial glycerides, whereby the stability of the compound(s) is improved and the processability thereof into food and drink, pharmaceutical preparations, non-pharmaceutical preparations,
cosmetics etc. is also improved.