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54 results about "Gastrointestinal infections" patented technology

Gastrointestinal infections occur when a person consumes bacteria or parasites that are harmful to the gastrointestinal system. A person who has ingested a harmful bacteria or parasite may suffer from common gastrointestinal infection symptoms such as diarrhea, fever and vomiting.

Probiotic lactic acid bacterium to treat bacterial infections associated with SIDS

Compositions including a non-pathogenic lactic acid-producing bacteria, such as a Bacillus species, spores or an extracellular product of B. coagulans, formulated for oral administration to the intestinal tract for inhibiting bacterial gastrointestinal infections are described. Methods and systems using the compositions for treating gastrointestinal infections, particularly sudden infant death syndrome (SIDS) are also disclosed.
Owner:GANEDEN BIOTECH

Anti-Adhesive Compounds to Prevent and Treat Bacterial Infections

The present invention provides compounds and compositions capable of inhibiting the attachment of Gram-negative bacteria on a host epithelium. Accordingly, said compounds and compositions can for example be used for the manufacture of a medicament to treat urinary, lung and gastrointestinal infections caused by said Gram-negative bacteria
Owner:VLAAMS INTERUNIVERSITAIR INST VOOR BIOTECHNOLOGIE VZW +1

Use of avian antibodies

The present invention relates to a novel method for treatment and prophylaxis of infections, especially enteric infections, in newborns, which is both safe and effective. This is achieved by using IgY directed against microbes, in particular against Enterobacter cloacae, which have been obtained by hyperimmunising birds with an antigen (microbe) in order to stimulate the production of immunoglobulines (IgY) against such microbe. The present invention also relates to a pharmaceutical product from eggs of birds containing immunoglobuline or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.
Owner:IMMUNSYST IMS

LOCAL ADMINISTRATION OF CHICKEN YOLK IMMUNE GLOBULINS (IgY) TO TREAT AND PREVENT FUNGAL INFECTIONS

InactiveUS20100233162A1Easy to produceTreatment and prophylaxisEgg immunoglobulinsSenses disorderAntigenYolk
The present invention relates to a composition comprising IgY antibodies against at least two different fungi, the use of the composition for the preparation of a pharmaceutical especially for prophylaxis and / or therapy of all kinds of fungal infections, such as conditions caused by organisms belonging to the Candida genus or Aspergillus genus, especially of fungi that are less sensitive to antimycotica and a diagnotstic method using the IgY antibodies. Further it relates to immunisation of birds with a combination of at least two different species of fungi to the Candida genus or Aspergillus genus and a diagnostic method for fungi. It also relates to relates to a novel method for treatment and / or prophylaxis of fungal infections, especially infections by fungi which have lowered sensitivity or resistance to antimycotics. The method is both safe and effective. This is achieved by using IgY directed against fungi, in particular against Candida species, which have a lowered sensitivity or resistance against antimycotics. The specific IgY has been obtained by hyper immunising birds with one or several fungi as antigen in order to stimulate the production of immune globulins (IgY) against such fungi. The present invention also relates to a pharmaceutical product from eggs of birds containing immune globulin or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.
Owner:BENGT AGERUP

Anti-enzymolysis antibacterial peptide II4II and preparation method and application thereof

ActiveCN111454334AThe experimental technical route is simpleAvoid restriction sitesAntibacterial agentsPeptide/protein ingredientsDiseaseChymase
The invention belongs to the technical field of biology and provides an anti-enzymolysis antibacterial peptide II4II and a preparation method and application thereof. The amino acid sequence of the antibacterial peptide II4II is shown in SEQ ID No. 1. The preparation method comprises the following steps of reasonably arranging amino acids in the sequence based on specific restriction enzyme cutting sites of trypsin, chymotrypsin and pepsin and basic characteristics of the antibacterial peptide, and selecting Ile as a hydrophobic amino acid to obtain the antibacterial peptide II4II. The invention further provides application of the antibacterial peptide II4II in preparation of medicines for treating gastrointestinal tract infection diseases caused by gram-negative bacteria or / and gram-positive bacteria. The antibacterial peptide II4II has a relatively good inhibition effect on multiple bacteria, is relatively low in hemolytic activity, has a treatment index of 80.63, has relatively goodanti-enzymolysis property, is kept unchanged in antibacterial activity after being treated by trypsin, chymotrypsin or pepsin, and has application potential as an antibiotic substitute.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Vaginal lactobacillus medicant

Disclosed are novel isolated strains of bacteria of the genus Lactobacillus which are useful in a vaginal medicant. Also disclosed are medicants containing such Lactobacilli, a novel preservation matrix for microorganisms, a method for preserving microbial cells within a medicant, and methods for preventing and treating vaginal and gastrointestinal infections.
Owner:SUZHOU OSEL BIO PHARM

Bile acid recycling inhibitors for treatment of gastrointestinal infections

Provided herein are methods for treating or preventing gastrointestinal and / or liver infections utilizing bile acid transport inhibitors and / or enteroendocrine peptide enhancing agents and / or FXR agonists. Also provided herein are methods for increasing the levels of an enteroendocrine peptide or hormone in an individual suffering from a gastrointestinal infection or liver infection utilizing bile acid transport inhibitors and / or enteroendocrine peptide enhancing agents and / or FXR agonists.
Owner:LUMENA PHARMA INC

Compound neomycin sulphate solution and preparation method thereof

The invention discloses a compound neomycin sulphate solution and a preparation method thereof. The invention aims to provide a compound neomycin sulphate solution which has obvious effect on treating gastrointestinal infection of birds, treats symptoms and a root and reduces the medicine application frequency and a preparation method thereof. 100 L of solution comprises 2-15 kg of neomycin sulphate, 3-15 kg of colistin sulphate, 0.01-0.05 kg of scopolamine methobromide, 10 kg of alcohol with concentration of 95 percent and the balance of purified water. The invention adopts the neomycin sulphate and the colistin sulphate as antibacterial components, has double effects, can effectively reduce the medicine resistant rate of bacteria and has effect on common Gram negative bacteria causing intestinal infection; and the scopolamine methobromide inhibits glandular secretion, dries intestinal contents and lightens a dehydration symptom so as to have a rapid therapeutic effect.
Owner:TIANJIN SHENGJI GRP CO LTD

Compositions for use in the prevention or treatment of gastrointestinal infections/inflammations in infants or young children

The present invention relates to a nutritional composition comprising at least one fucosylated oligosaccharide and at least one N-acetylated oligosaccharide in a particular ratio, for use in preventing and / or treating gastrointestinal infections and / or gastrointestinal inflammations in an infant or a young child.
Owner:SOC DES PROD NESTLE SA

Compound norfloxacin nicotinic soluble powder and preparation method thereof

The invention discloses compound norfloxacin nicotinic soluble powder and a preparation method thereof, and provides soluble powder capable of treating poultry gastrointestinal infection and lowering drug resistance probability and the preparation method thereof. The compound norfloxacin nicotinic soluble powder is prepared from the following raw materials in percentage by weight: 3-10% of norfloxacin nicotinate, 5-15% of neomycin sulfate, 5% of sodium chloride, 5% of potassium chloride and the balance anhydrous glucose. In the invention, the norfloxacin nicotinate and the neomycin sulfate are taken as antibacterial ingredients, thus achieving double efficacies and effectively reducing the probability of bacterial drug resistance, wherein, the norfloxacin nicotinate can be absorbed into the bloodstream for killing pathogenic bacteria through circulation secretion, and the neomycin sulfate is rarely absorbed by oral administration and directly applied to intestinal tract for producing contact sterilization effect, so the norfloxacin nicotinate and the neomycin sulfate have good effect of killing the pathogenic bacteria resulting in the poultry gastrointestinal infection from the two aspects; and the combination of the sodium chloride and the potassium chloride can make up electrolyte loss caused by excessive diarrhea of infected poultry. Therefore, the combination of the drugs can strengthen the curative effect on the poultry bacterial gastrointestinal infection.
Owner:TIANJIN SHENGJI GRP CO LTD

Secretory iga compositions, methods of making and methods of use thereof

Described herein is secretory IgA isolated from the intestinal luminal fluid and intestinal mucosal of animals such as pigs and cows. Also included are methods of isolating secretory IgA. The secretory IgA is useful in food compositions such as animal and human food compositions as well as pharmaceutical compositions to increase growth rate, improve feed efficiency, reduce gastrointestinal inflammation, reduce a risk of gastrointestinal infection in the animal, or a combination thereof.
Owner:WISCONSIN ALUMNI RES FOUND

Compound niacin norfloxacin injection and preparation method

The invention discloses a compound norfloxacin nicotinate injection which is applicable to the treatment of bacterial gastrointestinal infection of pigs, cattle, sheep and horses, and a preparation method thereof. The compound norfloxacin nicotinate injection is composed of 80-150 parts of norfloxacin nicotinate, 20-80 parts of apramycin sulfate and 5-30 parts of scopolamine hydrobromide. The preparation method is as follows: the components are weighted according to the weight, 300 parts of water for injection are taken, and the norfloxacin nicotinate, the scopolamine hydrobromide and the apramycin sulfate are sequentially added for stirring and dissolution; the mixture is maintained for 15 -20min, the pH value is regulated to 5.0-7.0, and the water for injection is added till 1000 parts after the clarification of liquid medicine for the preparation. The compound preparation is effective and has high efficiency for bacterial diarrhoea of pigs, cattle, sheep and horses, and the compound preparation can treat both manifestation and root cause of disease and alleviate the body stress reaction of affected animals.
Owner:TIANJIN SHENGJI GRP CO LTD

Traditional Chinese medicine composition with antibacterial and antiphlogistic effect

The invention provides a traditional Chinese medicine composition with antibacterial and antiphlogistic effect, which is prepared from 76.5-261.45 parts of rhubarb, 45-107.1 parts of rhizoma imperatae, 22.5-50.4 parts of licorice, 5-10 parts of pharmaceutically acceptable chloride ion neutralizer, 10-15 parts of pharmaceutically acceptable heavy-metal chelating agent, 15-30 parts of acid agent, 20-40 parts of alkali agent and 2-5 parts of pharmaceutically acceptable lubricant, wherein the acid agent and the alkali agent are pharmaceutically acceptable disintegrating agents. The rhubarb, the rhizoma imperatae and the licorice with meridian tropism in lung and stomach are traditional Chinese herbal medicine, taste bitter and sweet, are cold in nature and have antibacterial and antiphlogistic effect. In addition, the rhubarb, the rhizoma imperatae and the licorice mutually compensate and have obvious effect on treating respiratory diseases, gastrointestinal infections and other diseases of livestock and poultry, and the livestock and the poultry can not be easily resistant to the traditional Chinese medicine composition.
Owner:南通市鑫海水产养殖专业合作社

Novel fucoidan oligosaccharides as well as preparation method and application thereof

The invention discloses novel fucoidan oligosaccharides as well as a preparation method and application thereof. The novel fucoidan oligosaccharides comprises a chain formed by connecting four fucose residues in sequence, wherein the fucose residues are alternately chemically combined from 1 to 3 and 1 to 4; the sulfate radical is distributed on C2 and C3 of the second fucose residue and C2 of the third fucose residue. The quantity of the fucose residues (fixed structures) in the fucoidan oligosaccharides provided by the invention is equal to 4 or 6, so that the amount of the fucoidan oligosaccharides with the fixed structures is enlarged, and the use range of the fucoidan oligosaccharides is expanded; more component sources are supplied to medicines for preventing or treating atopic dermatitis and eczema and gastrointestinal infection.
Owner:BIOLOGY INST OF SHANDONG ACAD OF SCI +1

Methods of detecting markers for inflammatory conditions and food sensitivity in companion animals

The present invention provides methods and systems to accurately detect and measure levels of endogenous antibodies, for examples endogenous IgA, to particular antigens in a biological sample from a companion animal, which is useful to diagnose inflammatory conditions, including bowel disease (IBD), gastrointestinal infections, and food sensitivities in companion animals, e.g., dogs or cats, and to distinguish among such gastrointestinal disorders. Such methods and systems identify whether a sample from the patient is associated with an inflammatory condition, infection, and / or food sensitivity condition, by using non-invasive means, thus conveniently providing information useful for guiding treatment decisions.
Owner:VETICA LABS INC

Composition containing probiotics metabolite

The invention relates to a composition containing probiotics metabolite. The composition is prepared from, by weight, 1-10 parts of probiotics metabolite, 2-3 parts of oligosaccharide and 3-8 parts ofpowder or liquid containing egg yolk antibody. Compared with the prior art, the composition containing the probiotics metabolite has the advantages that the waste discharge can be reduced, the wasteis turned into treasure, the bacteria reproduction can be selectively inhibited, and the composition is used for preventing or curing gastrointestinal infection caused by escherichia coli of piglets,salmonella, clostridium perfringens, porcine transmissible gastroenteritis virus, porcine epidemic diarrhea virus, porcine rotavirus and the like.
Owner:FUJIAN AONONG BIOLOGICAL TECH GRP CO LTD +1

Non-invasive monitoring system

A wearable device for non-invasive monitoring of the presence, amount, and / or concentration of an analyte in a sample from a user of the device is described. The analyte is selected to be indicative of or related to a physiological status of a user. Relevant physiological status include hypoglycemia, infection, respiratory infection, urinary infection, gastrointestinal infection, obesity, diabetes, type I diabetes and type II diabetes.
Owner:AERBETIC INC

Local administration of chicken yolk immune globulins (igy) to treat and prevent fungal infections

The present invention relates to a composition comprising IgY antibodies against at least two different fungi, the use of the composition for the preparation of a pharmaceutical especially for prophylaxis and / or therapy of all kinds of fungal infections, such as conditions caused by organisms belonging to the Candida genus or Aspergillus genus, especially of fungi that are less sensitive to antimycotica and a diagnotstic method using the IgY antibodies. Further it relates to immunisation of birds with a combination of at least two different species of fungi to the Candida genus or Aspergillus genus and a diagnostic method for fungi. It also relates to relates to a novel method for treatment and / or prophylaxis of fungal infections, especially infections by fungi which have lowered sensitivity or resistance to antimycotics. The method is both safe and effective. This is achieved by using IgY directed against fungi, in particular against Candida species, which have a lowered sensitivity or resistance against antimycotics. The specific IgY has been obtained by hyper immunising birds with one or several fungi as antigen in order to stimulate the production of immune globulins (IgY) against such fungi. The present invention also relates to a pharmaceutical product from eggs of birds containing immune globulin or a fragment thereof, which can be combined with other preparations, nutritients or pharmaceuticals for simultaneous, separate or sequential use in the prophylaxis or therapy of gastrointestinal infections in newborn infants.
Owner:ОГЕРУП БЕНГТ

Intraluminal therapy system for gastrointestinal infections

A novel intraluminal therapy system for providing a quick and effective way to treat gastrointestinal infections. The invention includes a brand new system of treating Helicobacter pylori infections and an agent dispenser for an endoscope apparatus, comprising a pump, a catheter connected to the pump and a nozzle connected to the catheter. The devices are used along with a complex of antibiotic and / or antimicrobial agents to eradicate Helicobacter pylori while performing an endoscopic procedure.
Owner:MACKAY MEMORIAL HOSPITAL

Pharmaceutical compositions and methods for treating gastrointestinal infections and disorders

Methods of treating gastrointestinal disorders, in a patient in need thereof, including disorders of the liver and pancreas, using an amount of an orally dosed TLR-7 compound in an amount sufficient to increase IFN in the gastrointestinal area, including the liver, but not significantly increasing systemic IFN.
Owner:GILEAD SCI INC
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