The invention provides an anti-interference electrocardiogram inspection device, which relates to the field of electrocardiograph, and solves the problem that when the existing electrocardiogram inspection device is in use, the sandpaper cannot be automatically attached to the skin to remove the stratum corneum, and the sandpapers of different models and sizes cannot be fixed. The problem includes the main body; the main body is the body of the electrocardiogram inspection device, and the main body is a T-shaped structure, and supports are installed at both ends of the bottom of the main body. When the device is in use, insert the sandpaper into the bottom groove, and then the pressing plate receives the spring force to move downward, so that the rubber contact block can press and fix both ends of the sandpaper, and then pull the control rod to move up, so that the rod can be in the The inside of the inner groove moves, and then pulls the block to retract, so that the side piece can be released from the limit, push the bottom of the side piece and the sandpaper to move down, so that the sandpaper can automatically close to the chest and abdomen of the human body, and then control the movement of the main body, so that the sandpaper can be moved. Easily remove cuticles.