78 results about "Biological clock" patented technology

Anti-aging compositions and methods for delivering (engrafting) younger compatible human DNA to tissues, through the systematic periodic introduction of younger primordial whole (nucleated) stem cells and bone marrow into a recipient, resulting in re-establishment of an earlier relative biological clock set-point, with respect to the number of cell generations-divisions are disclosed.

The invention offers a technique that selectively differentiation-induces mesenchymal stem cells, which can differentiate to cells that constitute various tissues and organs, to osteoblasts. In addition, the invention offers a technique that differentiation-induces mesenchymal stem cells to osteoblasts with a simple operation that needs only short time and that is noninvasive. The inventors have found that the switch for the differentiation induction to osteoblasts is turned on by translocating biological clock-relevant factors existing in mesenchymal stem cells from the cells' cytoplasm to the cells' nucleus. The inventors have also found that the switch can be turned on by irradiating the cells for a short time with a lightwave having a specific wavelength that is noninvasive.

A composition having a normalizing action for infradian rhythm and / or a synchronization promoting action for circadian rhythm (biological clock) containing arachidonic acid and / or an arachidonic acid-containing compound.

The invention relates to the technical field of traditional Chinese medicines, in particular to a gegen-qinlian decoction water extract for regulating an obese body. The gegen-qinlian decoction waterextract is obtained from puerarin, radix scutellariae, coptidis rhizome and radix liquiritiae through medicinal material compatibility and water decoction; the medicinal material compatibility is calculated by the following materials in parts by mass: 7-9 parts of the puerarin, 2-4 parts of the radix scutellariae, 2-4 parts of the coptidis rhizome, and 1-3 parts of the radix liquiritiae; the gegen-qinlian decoction water extract is used for preparing drugs to regulate intestinal flora and liver biological clock genes of intestine damp heat of the obese body, and has the effect of reversing Akkermansia and Lactobacillus, at the same time, the expression and transcription level of liver Clock and Arntl genes is up-regulated, the level of body serum triglyceride can be effectively reduced, and the gegen-qinlian decoction water extract has a regulatory effect on total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, blood glucose, insulin and other blood lipid and blood glucose indexes, and also has a regulatory effect on short chain, medium chain and long chain fatty acids, tryptophan, kynurenine, cannabinoid and other metabolites of the body.

The invention discloses a multi-sport physiological sign zero-gravity airplane comprehensive test. A human body operation sport characteristic testing support, an equipment platform, a treadmill, a visual perception characteristic testing system and a biological rhythm influence testing platform are included. Performance data formed during pushing, pulling and two-arm rotation operation of a person in the zero-gravity flight state can be obtained, and verification of a biomechanical model in the zero-weight environment is supported; force distribution data of shoulder and waist portions of a treadmill testee are measured and obtained, bases are provided for improving and perfecting a treadmill bonding system, and the problems existing in the design of an aerospace treadmill are further analyzed by comparing the difference between the running motion gestures on the ground and the zero-weight airplane; the performance data obtaining effectiveness of the visual perception characteristic testing system in the variable-weight environment is verified. The influence of short and repeated zero weight simulated by the zero-weight airplane on model organism gravity stress gene expression and biological rhythm is discussed, and a molecular mechanism of a biological clock affected by gravity changes is discovered.

The invention provides a supervisory system for disease prevention of pigs. The supervisory system collects body surface temperature and motion information of the pigs in real time through a data collection system, transmits the body surface temperature and the motion information to a server module through a communication base station, performs intelligent analysis in the server module, judges temperature and behaviors, and sends results to a WEB service module or an APP of a mobile phone. Therefore, a set of biological clock model is established for each pig, a health state or a disease stateof the pigs is obtained in real time, and a forecasting system for automatic body temperature and activity detection is formed; when a certain pig is abnormal, warning information is actively sent tobreeding personnel, so that the labor cost is saved for a breeding farm; and meanwhile, vital signs of the pig can be monitored around the clock, so that real-time monitoring of the pig is achieved,the breeding risk of the farm is reduced, early discovery, early prevention and early treatment of diseases are achieved, the death rate is reduced, and economic losses are avoided.

The invention provides a soybean biological clock gene GmFKF2 protein, (1) the protein is composed of amino acid sequences represented in the SEQ ID NO.1; (2) or the protein is derived from the protein mentioned in (1) through substituting, losing or adding one or several amino acids in the amino acid sequence represented in the SEQ ID No.1, and has the same activity as that of the protein mentioned in (1). The invention at the same time provides a gene GmFKF2, which encodes the protein mentioned above, through over-expressing the gene, plant blossom can be prominently promoted, and the growth period can be prolonged. The soybean biological clock gene GmFKF2 and encoding protein thereof can be used to solve the problems of flowering asynchronism in the crossbreeding process, growth period control of various plants, vegetables, fruits, and flowers, photoperiod sensitivity, and species introduction.

A method of increasing gene expression by manipulating the circadian clock is described that includes transforming a photosynthetic organism to include an expression control sequence that modulates the expression of a clock gene to increase expression of a target gene. Photosynthetic organism having a modified circadian cycle reflecting this method are also described.