An insecticide composition is aqueous emulsion comprising the main active components of acetamiprid 0.1-10% and benzalkonium bromide 5-80%, fitted with other auxiliary agents. The insecticide composition of the invention has great curative effect for fin rot, hemorrhage and other diseases of various fishes, shrimps, crabs, turtles, ricefield eels and the like, caused by helminthes and bacteria viruses, and can effectively kill various germs and viruses harmful for aquatic organisms and variant germs, viruses, harmful bacterium spores and algae spores caused by deteriorated environment. The insecticide composition has great killing effect to trichodina, doctylogyrosis and other helminthes harmful for fishes, and can be utilized in mixed culturing pond of fishes, shrimps, crabs and the like. The insecticide composition of the invention has wide insecticidal sterilization spectrum, is safe and reliable in utilizing, has stable performance, and is convenient for utilizing.