In order to solve the problems of low CTP plate manufacturing efficiency and poor plate surface adhesive force in the prior art, the invention provides a manufacturing device for a treatment-free plate for printing. The manufacturing device comprises an aluminum roll replacing device, a washing device, an acid pickling device, an electrolysis device, a water spraying device, an ash removal device,an oxidation device, a hole sealing device, a drying device, a gluing device and a slitting device. Through the arrangement of the aluminum roll replacing device, the replacing steps are decreased, the replacing speed is increased, and the non-stop roll replacing effect is achieved; the electrolysis device is provided with a spraying box, the spraying box can assist a spraying opening in workingwell, and electrolyte can flow out uniformly through the spraying opening to improve the adhesive force of an aluminum plate base; and a water spraying box is arranged in the water spraying device, and double-face spraying can be conducted on the aluminum plate base, so that the spraying efficiency is improved, the spraying speed is increased, the surface of the aluminum plate base is stressed more uniformly through double-face spraying, and the improvement of the adhesive force of the aluminum plate base can be assisted.