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53results about How to "Passage increase" patented technology

Targeted release of nitric oxide in the CNS circulation for modulating the BBB and treating disorders

A method for delivering molecules to a central nervous system (CNS) of a subject includes supplying the molecules to a blood circulation of the CNS; supplying, to a body of the subject, a carrier system that encapsulates a nitric oxide (NO) facilitator; and applying energy to the carrier system at an energy level sufficient to cause the carrier system to release the NO facilitator in a blood circulation of the subject in a vicinity of a blood-brain barrier (BBB) of the subject and thereby increase passage of the molecules from the blood circulation of the CNS, through the BBB, and into the CNS of the subject.
Owner:BRAINSGATE LTD

High contrast optoacoustical imaging using nonoparticles

InactiveUS20050175540A1Maximize both the optical absorbanceIncrease the effective absorbanceUltrasonic/sonic/infrasonic diagnosticsSurgeryNanoparticleSpherical shaped
A method of enhancing detection for a specific object in a body. A nanoparticulate is administered to the body for location in an area to be explored for detection of the object, if present. The nanoparticulate is at least partially metallic, has a formed non-spherical shape having a minimal characteristic dimension in the range from about 1 to about 3000 nanometers, and has a formed composition capable of producing thermal pressure either in the nanoparticulate or in the object greater than the object could produce in the absence of the nanoparticulate. Electromagnetic radiation is directed into the body. The electromagnetic radiation has a specific wavelength or spectrum of wavelengths in the range from 300 nm to 300 mm selected so that the wavelength or wavelength spectrum is longer by a factor of at least 3 than the minimum characteristic dimension of the nanoparticulate. The nanoparticulate absorbs the electromagnetic radiation more than would one or more non-aggregated spherically shaped particles of the same total volume with a composition identical to the nanoparticulate. The nanoparticulate produces an enhanced optoacoustic signal resulting from the absorption that is received and converted into an electronic signal and presented for assessment of the at least one parameter by a human or a machine
Owner:SENO MEDICAL INSTR

High contrast optoacoustic imaging using nanoparticles

InactiveUS7500953B2Maximize both the optical absorbanceIncrease the effective absorbanceUltrasonic/sonic/infrasonic diagnosticsSurgeryNanoparticleElectromagnetic radiation
A method of enhancing detection for a specific object in a body. A nanoparticulate is administered to the body for location in an area to be explored for detection of the object, if present. The nanoparticulate is at least partially metallic, has a formed non-spherical shape having a minimal characteristic dimension in the range from about 1 to about 3000 nanometers, and has a formed composition capable of producing thermal pressure either in the nanoparticulate or in the object greater than the object could produce in the absence of the nanoparticulate. Electromagnetic radiation is directed into the body. The electromagnetic radiation has a specific wavelength or spectrum of wavelengths in the range from 300 nm to 300 mm selected so that the wavelength or wavelength spectrum is longer by a factor of at least 3 than the minimum characteristic dimension of the nanoparticulate. The nanoparticulate absorbs the electromagnetic radiation more than would one or more non-aggregated spherically shaped particles of the same total volume with a composition identical to the nanoparticulate. The nanoparticulate produces an enhanced optoacoustic signal resulting from the absorption that is received and converted into an electronic signal and presented for assessment of the at least one parameter by a human or a machine.
Owner:SENO MEDICAL INSTR

Engine coolant changing system

An engine cooling system liquid insertion and removal system has an adapter disposed in a vehicle radiator service opening via which old coolant is removed from the engine system by partial vacuum applied to an old coolant container via a conduit. New coolant is introduced via the adapter by atmospheric pressure from a portable container. Conduits interconnect the engine cooling system, the old and new coolant containers, and a source of partial vacuum applied to conduits.
Owner:DOTY ROBERT A +2
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