Systems and methods for treating an occluding
thrombus in a
blood vessel of a patient. Ferrofluids having magnetic particles dispersed therein are introduced locally via a
catheter, a micro-
catheter, or intravenously, to the bloodstream of a patient. The ferrofluids are magnetically manipulated or moved throughout the blood vessels of the patient by an external
magnetic field generator until the intended occluding
thrombus is broken up and removed. The external
magnetic field generator, which can be stationary or portable, creates a vortex,
high velocity jets, or other motion, within the ferrofluids, by rotating or moving at least one
magnet relative to the patient. The at least one
magnet is provided in the
magnetic field generator. The vortex,
high velocity jets, or other motion of the ferrofluids are used to break-up and remove the occluding
thrombus. Drugs or
abrasive particles, or both, may be incorporated with the ferrofluids and delivered to the bloodstream with the ferrofluids to help break-up and remove the occluding thrombus as well. Upon removal of the thrombus,
magnetic components of the ferrofluids may remain in the patient or may be magnetically recaptured and removed from the bloodstream.