The invention discloses a hydraulic linkage type plunger pushing mechanism and a plunger diaphragm pump using the same, the mechanism is provided with a crankshaft which is installed in a low-pressure liquid cavity of a plunger diaphragm pump body through a bearing assembly, the crankshaft is provided with an eccentric part, and the eccentric part of the crankshaft is sleeved with a bearing. According to the plunger diaphragm pump, the hydraulic linkage type plunger pushing mechanism is arranged, so that the problem that mechanical abrasion of a swash plate pushing head driving type hydraulic unit in a traditional plunger diaphragm pump is large is solved through the crankshaft, bearing and eccentric design, the bearing is arranged at the eccentric position of the crankshaft, and the outer ring of the bearing and the pushing head are tightly attached and do not generate relative movement; relative movement is achieved through the rolling bearings, the crankshaft pushes the corresponding plungers through the rolling bearings to complete compression action, outer rings of the bearings are not directly abraded with the plungers, factors of oil temperature rise caused by large mechanical action range of a traditional swash plate pushing head and large mechanical abrasion caused by sliding friction are avoided, the oil temperature in a low-pressure liquid cavity is greatly reduced, and the service life of the crankshaft is prolonged. And the oil temperature of the low-pressure liquid chamber is not obviously increased in the actual operation process.