37results about How to "Good controllable release" patented technology

The invention relates to a temperature-responsive three-dimensional ordered macroporous controlled-release material. The apertures of a macropore and a communicating window of the controlled-release material are uniform, wherein the aperture of the macropore is 100-1000nm, the communicating window has a size of 40-120nm and the pore volume is 1.3-2.8cm<3> / g; and a substrate of the controlled-release material is monodisperse three-dimensional ordered macroporous crosslinked polystyrene with mutually communicated windows, a polymer chain segment with temperature responsiveness is introduced onto the substrate through an atom transfer radical activity-controlled graft polymerization method, and the on-off control of the communicating window between macropores is realized by utilizing the extending-curling action of the temperature-responsive polymer chain segment under different temperatures: a macroporous chain gradually shrinks along with the temperature rise, the pore window graduallyopens, and furthermore, the controlled-release action on filled and packaged substances is achieved. The temperature-responsive three-dimensional ordered macroporous controlled-release material has extensive application values in the fields of controlled-release of biomedicines, drug controlled-release systems, controlled release-embedding of active enzyme and catalysts, and the like.

The present invention provides a carbon monoxide donor molecule with fluorescent properties and a preparation method and application thereof. The carbon monoxide donor molecule with the structure represented by the formula (I) provided by the present invention can realize a responsive protection element in the next step under illumination conditions The removal of carbon monoxide and the release of carbon monoxide, and the carbon monoxide donor molecule can be further prepared to obtain a stable polymer, which can be further prepared into a water-stable assembly material by self-assembly. Compared with the existing carbon monoxide For releasing molecules, the carbon monoxide donor provided by the present invention has good controllable release and good biocompatibility.

The invention relates to the field of chemical technique, especially to a production method for preparing dipotassium hydrogen phosphate and a by-product a special fertilizer for plum trees. By changing coefficients such as temperature and the like of wet-process phosphoric acid preparation of dipotassium hydrogen phosphate, purity of the product dipotassium hydrogen phosphate is raised, a compound fertilizer containing N, P and K combined forms can simultaneously be produced, and formaldehyde is added into a filtrate to prepare a controlled-release compound fertilizer. By the method, purity of dipotassium hydrogen phosphate can be raised, and the produced special fertilizer for plum trees has good absorptivity. Meanwhile, the produced special fertilizer for plum trees can meet nutritional requirements of each period of growth cycle of plum trees, and is an efficient compound fertilizer.

The invention relates to a manganese-zinc-ferrite targeting nano-composite carrier and a preparation method thereof. The preparation method is characterized in that a chemical co-precipitation methodis used to composite chitosan and gamma-polyglutamic acid with manganese-zinc ferrite, and particles below 100 nanometers are generated after the crosslinking reaction of the three substances above. The preparation method has the advantages that the method is simple to operate, the prepared manganese-zinc-ferrite targeting nano-composite carrier has a typical core-shell structure, the manganese-zinc-ferrite targeting nano-composite carrier which is magnetic nanocrystals can have targeting and sustained-release ability by changing the magnetic field and temperature, and the manganese-zinc-ferrite targeting nano-composite carrier is more promising in actual clinical application prospect as compared with the single manganese-zinc ferrite.

The invention relates to the technical field of chemical industry, and especially relates to a method for preparing potassium dihydrogen phosphate and preparing a special fertilizer for plums as a byproduct. The temperature and other coefficients of the preparation technology of potassium dihydrogen phosphate from phosphoric acid through a wet process are changed, so the purity of the potassium dihydrogen phosphate product is improved, and the N, P and K compounded fertilizer is produced. The method improves the purity of potassium dihydrogen phosphate, and the produced special fertilizer for plums has high absorptivity; and formaldehyde is added to a filtrate to prepare the controlled release compound fertilizer. The produced special fertilizer for plums can meet the nutrition needs of plums in all stages of the growth period of plums, greatly increases the output of plums, and is an efficient compound fertilizer.

The invention discloses nano-drug carrier particles capable of controlling drug release. The particles have a core-shell structure, wherein a gold nano-cage (1) which is provided with a mesoporous surface and has a hollow structure is arranged in the innermost layer; a polymer PAH layer (2) carrying positive electricity is used for modifying the surface of the gold nano-cage (1); a pH sensitive lipid layer (3) is arranged on the outer surface coating layer of the polymer PAH layer (2). Under pH and light external excitation trigger, gating is switched from a 'closed' state to an 'open' state, and drug molecules are released. The carrier particles can be used for effectively improving the efficiency of cancer chemotherapy.