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37results about How to "Good controllable release" patented technology

Temperature-responsive three-dimensional ordered macroporous controlled-release material

The invention relates to a temperature-responsive three-dimensional ordered macroporous controlled-release material. The apertures of a macropore and a communicating window of the controlled-release material are uniform, wherein the aperture of the macropore is 100-1000nm, the communicating window has a size of 40-120nm and the pore volume is 1.3-2.8cm<3> / g; and a substrate of the controlled-release material is monodisperse three-dimensional ordered macroporous crosslinked polystyrene with mutually communicated windows, a polymer chain segment with temperature responsiveness is introduced onto the substrate through an atom transfer radical activity-controlled graft polymerization method, and the on-off control of the communicating window between macropores is realized by utilizing the extending-curling action of the temperature-responsive polymer chain segment under different temperatures: a macroporous chain gradually shrinks along with the temperature rise, the pore window gradually opens, and furthermore, the controlled-release action on filled and packaged substances is achieved. The temperature-responsive three-dimensional ordered macroporous controlled-release material has extensive application values in the fields of controlled-release of biomedicines, drug controlled-release systems, controlled release-embedding of active enzyme and catalysts, and the like.
Owner:HEBEI UNIV OF TECH

Ph-responsive three-dimensional ordered macroporous controlled-release material

The invention relates to a pH-responsive three-dimensional ordered macroporous controlled-release material. The sizes of macropores and communicating windows of the pH-responsive three-dimensional ordered macroporous controlled-release material are uniform, the sizes of the macropores are 100-1000nm, the sizes of the communicating windows are 40-120nm, and the pore volume is 1.3-2.8 cm<3> / g; the substrate is monodisperse three-dimensional ordered macroporous crosslinked polystyrene with windows which are mutually communicated, and a pH-responsive polymer chain section is introduced into the substrate by an atom transfer free-radical activity-controllable graft polymerization method; and the uncurling-curling action of the pH-responsive polymer chain section under different pH values is utilized to control the opening and closing of the communicating windows among the macropores: as the pH value increases, macromolecule chains gradually uncurl, and the pore windows are gradually closed, thereby realizing the controllable release of the contained filler. The pH-responsive three-dimensional ordered macroporous controlled-release material has wide application values in the controlled-release fields of biomedicine, medicine controlled-release systems, organized enzymes, slow release-embedding of catalysts, and the like.
Owner:HEBEI UNIV OF TECH

Nano-drug carrier particles capable of controlling drug release and preparation method thereof

The invention discloses nano-drug carrier particles capable of controlling drug release. The particles have a core-shell structure, wherein a gold nano-cage (1) which is provided with a mesoporous surface and has a hollow structure is arranged in the innermost layer; a polymer PAH layer (2) carrying positive electricity is used for modifying the surface of the gold nano-cage (1); a pH sensitive lipid layer (3) is arranged on the outer surface coating layer of the polymer PAH layer (2). Under pH and light external excitation trigger, gating is switched from a 'closed' state to an 'open' state, and drug molecules are released. The carrier particles can be used for effectively improving the efficiency of cancer chemotherapy.
Owner:SOUTHEAST UNIV

Magnetotactic bacterium quantum dot microcapsule and preparation method thereof

The invention provides a magnetotactic bacterium quantum dot microcapsule. The inner core of the microcapsule is a magnetosome, the surface of the magnetosome is coated with a uniform and compact compound of chitosan oligosaccharide / gamma-polyglutamic acid / carbon quantum dots, and the mass ratio of the magnetosome to chitosan oligosaccharide to gamma-polyglutamic acid to carbon quantum dots is 1:(1-3):(10-20):1. The preparation method of the magnetotactic bacterium quantum dot microcapsule is easy to operate, the obtained magnetosome and carbon quantum dot intelligent microcapsule represent typical core-shell structures, and the quantum dot microcapsule has the targeting and slow releasing capability, and has huge clinical application prospects.
Owner:QUFU NORMAL UNIV

Manganese-zinc-ferrite targeting nano-composite carrier and preparation method thereof

The invention relates to a manganese-zinc-ferrite targeting nano-composite carrier and a preparation method thereof. The preparation method is characterized in that a chemical co-precipitation methodis used to composite chitosan and gamma-polyglutamic acid with manganese-zinc ferrite, and particles below 100 nanometers are generated after the crosslinking reaction of the three substances above. The preparation method has the advantages that the method is simple to operate, the prepared manganese-zinc-ferrite targeting nano-composite carrier has a typical core-shell structure, the manganese-zinc-ferrite targeting nano-composite carrier which is magnetic nanocrystals can have targeting and sustained-release ability by changing the magnetic field and temperature, and the manganese-zinc-ferrite targeting nano-composite carrier is more promising in actual clinical application prospect as compared with the single manganese-zinc ferrite.
Owner:QUFU NORMAL UNIV

Carbon monoxide donor molecule with fluorescent properties and preparation method and application thereof

The invention provides a carbon monoxide donor molecule with fluorescent properties and a preparation method and application thereof. The carbon monoxide donor molecule provided by the invention has structure as shown in a formula (I), can realize the removal of responsive protection elements and release of carbon monoxide in one step under illumination conditions, and is applicable to preparationof a stable high-molecular polymer which can be further used for preparing assembly material with a stable aqueous phase through self-assembling. Compared with conventional carbon monoxide releasingmolecules, the carbon monoxide donor provided by the invention is capable of realizing good controlled release and has good biocompatibility.
Owner:UNIV OF SCI & TECH OF CHINA

Production method for preparing monopotassium phosphate and by-product special fertilizer for Taxus chinensis

The invention relates to the field of chemical technique, especially to a production method for preparing monopotassium phosphate and a by-product a special fertilizer for Taxus chinensis. By changing coefficients such as temperature and the like of wet-process phosphoric acid preparation of monopotassium phosphate, purity of the product monopotassium phosphate is raised, and a compound fertilizer containing N, P and K combined forms can simultaneously be produced. In addition, formaldehyde is added into a filtrate to prepare a controlled-release compound fertilizer. By the method, purity of monopotassium phosphate can be raised, and the produced special fertilizer for Taxus chinensis has good absorptivity. Meanwhile, the produced special fertilizer for Taxus chinensis can meet nutritional requirements of each period of growth cycle of Taxus chinensis. The special fertilizer is an efficient compound fertilizer.
Owner:GUIZHOU UNIV +2

Method for preparing potassium dihydrogen phosphate and preparing special fertilizer for plums as byproduct

The invention relates to the technical field of chemical industry, and especially relates to a method for preparing potassium dihydrogen phosphate and preparing a special fertilizer for plums as a byproduct. The temperature and other coefficients of the preparation technology of potassium dihydrogen phosphate from phosphoric acid through a wet process are changed, so the purity of the potassium dihydrogen phosphate product is improved, and the N, P and K compounded fertilizer is produced. The method improves the purity of potassium dihydrogen phosphate, and the produced special fertilizer for plums has high absorptivity; and formaldehyde is added to a filtrate to prepare the controlled release compound fertilizer. The produced special fertilizer for plums can meet the nutrition needs of plums in all stages of the growth period of plums, greatly increases the output of plums, and is an efficient compound fertilizer.
Owner:GUIZHOU KAILIN GRP CO LTD +2

Production method of monopotassium phosphate with by-product welsh onion special fertilizer

The invention relates to the technical field of chemical industry, and in particular to a production method of monopotassium phosphate with a by-product welsh onion special fertilizer. Coefficients such as temperature in a wet process for preparation of monopotassium phosphate are changed to improve the purity of monopotassium phosphate product and to produce a compound fertilizer containing N, P and K in combined state; and a filtrate is adjusted into an acidic state, and is added into a formaldehyde solution to prepare a controlled release compound fertilizer. The method can improve the purity of monopotassium phosphate, besides the produced welsh onion special fertilizer has good absorption rate; and the produced welsh onion special fertilizer meets the nutritional needs of each period in the growth cycle, greatly increases welsh onion yield, and is a high efficient compound fertilizer.
Owner:GUIZHOU UNIV +2

Iridium nano intelligent composite medicine and preparation method thereof

The invention relates to an iridium nano intelligent composite carrier and a preparation method thereof, and belongs to the field of biomedicine. According to the method provided by the invention, chitosan oligosaccharide, gamma-polyglutamic acid and iridium nano-particles are compounded by adopting a high-temperature solution method, and particles below 100nm are generated after a crosslinking reaction of the three substances; the method is simple to operate; the obtained iridium nano targeted composite carrier presents a typical core-shell structure; the nano-crystals can have targeting andslow release capabilities by changing the pH value, and have a better future of clinical practical application compared with single iridium nano-particles.
Owner:QUFU NORMAL UNIV

Production method for preparing ammonium dihydrogen phosphate and by-product special fertilizer for chive

The invention relates to the field of chemical technique, especially to a production method for preparing ammonium dihydrogen phosphate and a by-product a special fertilizer for chive. By changing coefficients such as temperature and the like of wet-process phosphoric acid preparation of ammonium dihydrogen phosphate, purity of the product ammonium dihydrogen phosphate is raised, and a compound fertilizer containing N, P and K combined forms can simultaneously be produced. By the method, purity of ammonium dihydrogen phosphate can be raised, and the produced special fertilizer for chive has good absorptivity. Meanwhile, the produced special fertilizer for chive can meet nutritional requirements of each period of growth cycle of chive. By the use of the compound fertilizer, yield of chive is raised greatly. The special fertilizer is an efficient compound fertilizer.
Owner:GUIZHOU UNIV +2

Temperature-responsive three-dimensional ordered macroporous controlled-release material

The invention relates to a temperature-responsive three-dimensional ordered macroporous controlled-release material. The apertures of a macropore and a communicating window of the controlled-release material are uniform, wherein the aperture of the macropore is 100-1000nm, the communicating window has a size of 40-120nm and the pore volume is 1.3-2.8cm<3> / g; and a substrate of the controlled-release material is monodisperse three-dimensional ordered macroporous crosslinked polystyrene with mutually communicated windows, a polymer chain segment with temperature responsiveness is introduced onto the substrate through an atom transfer radical activity-controlled graft polymerization method, and the on-off control of the communicating window between macropores is realized by utilizing the extending-curling action of the temperature-responsive polymer chain segment under different temperatures: a macroporous chain gradually shrinks along with the temperature rise, the pore window graduallyopens, and furthermore, the controlled-release action on filled and packaged substances is achieved. The temperature-responsive three-dimensional ordered macroporous controlled-release material has extensive application values in the fields of controlled-release of biomedicines, drug controlled-release systems, controlled release-embedding of active enzyme and catalysts, and the like.
Owner:HEBEI UNIV OF TECH

Method for preparing ammonium dihydrogen phosphate and preparing special fertilizer for ginger as byproduct

The invention relates to the technical field of chemical industry, and especially relates to a method for preparing ammonium dihydrogen phosphate and preparing a special fertilizer for ginger as a byproduct. The temperature and other coefficients of the preparation of ammonium dihydrogen phosphate from phosphoric acid through a wet process are changed, so the purity of the ammonium dihydrogen phosphate product is improved, and the N, P and K compounded fertilizer is produced. The method improves the purity of ammonium dihydrogen phosphate, and the produced special fertilizer for ginger has high absorptivity, can meet the nutrition needs of ginger in all stages of the growth period of ginger, greatly increases the output of ginger, and is an efficient compound fertilizer.
Owner:GUIYANG KAILIN FERTILIZER CO LTD +2

Method for preparing potassium dihydrogen phosphate and preparing special fertilizer for peony as byproduct

The invention relates to the technical field of chemical industry, and especially relates to a method for preparing potassium dihydrogen phosphate and preparing a special fertilizer for peony as a byproduct. The temperature and other coefficients of the preparation technology of potassium dihydrogen phosphate from phosphoric acid through a wet process are changed, so the purity of the potassium dihydrogen phosphate product is improved, and the N, P and K compounded fertilizer is produced; and formaldehyde is added to a filtrate to prepare the controlled release compound fertilizer. The method improves the purity of potassium dihydrogen phosphate, and the produced special fertilizer for peony has high absorptivity, can meet the nutrition needs of peony in all stages of the growth period of peony, and is an efficient compound fertilizer.
Owner:GUIZHOU UNIV +2

Ph-responsive three-dimensional ordered macroporous controlled-release material

The invention relates to a pH-responsive three-dimensional ordered macroporous controlled-release material. The sizes of macropores and communicating windows of the pH-responsive three-dimensional ordered macroporous controlled-release material are uniform, the sizes of the macropores are 100-1000nm, the sizes of the communicating windows are 40-120nm, and the pore volume is 1.3-2.8 cm<3> / g; the substrate is monodisperse three-dimensional ordered macroporous crosslinked polystyrene with windows which are mutually communicated, and a pH-responsive polymer chain section is introduced into the substrate by an atom transfer free-radical activity-controllable graft polymerization method; and the uncurling-curling action of the pH-responsive polymer chain section under different pH values is utilized to control the opening and closing of the communicating windows among the macropores: as the pH value increases, macromolecule chains gradually uncurl, and the pore windows are gradually closed, thereby realizing the controllable release of the contained filler. The pH-responsive three-dimensional ordered macroporous controlled-release material has wide application values in the controlled-release fields of biomedicine, medicine controlled-release systems, organized enzymes, slow release-embedding of catalysts, and the like.
Owner:HEBEI UNIV OF TECH

Production method of monopotassium phosphate with by-product cinnamon special fertilizer

The invention relates to the technical field of chemical industry, and in particular to a production method of monopotassium phosphate with a by-product cinnamon special fertilizer. Coefficients such as temperature in a wet process for preparation of monopotassium phosphate are changed to improve the purity of monopotassium phosphate product and to produce a compound fertilizer containing N, P and K in combined state; and formaldehyde is added in a filtrate to prepare a controlled release compound fertilizer. The method can improve the purity of monopotassium phosphate, besides the produced cinnamon special fertilizer has good absorption rate; and the produced cinnamon special fertilizer meets the nutritional needs of each period in the growth cycle, greatly increases cinnamon yield, and is a high efficient compound fertilizer.
Owner:GUIZHOU KAILIN GRP CO LTD +2

A kind of production method for preparing potassium dihydrogen phosphate by-product chrysanthemum special fertilizer

The invention relates to the technical field of chemical industry, and especially relates to a method for preparing potassium dihydrogen phosphate and preparing a special fertilizer for chrysanthemum as a byproduct. The temperature and other coefficients of the preparation technology of potassium dihydrogen phosphate from phosphoric acid through a wet process are changed, so the purity of the potassium dihydrogen phosphate product is improved, the N, P and K compounded fertilizer is produced, a filtrate is adjusted to be acidic, and a formaldehyde solution is added to prepare the controlled release compound fertilizer. The method improves the purity of ammonium dihydrogen phosphate, and the produced special fertilizer for chrysanthemum has high absorptivity, can meet the nutrition needs of chrysanthemum in all stages of the growth period of chrysanthemum, greatly increases the output of chrysanthemum, and is an efficient compound fertilizer.
Owner:GUIZHOU UNIV +2
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