The invention discloses a preparation method of interior wall putty. The interior wall putty is composed of the following ingredients in parts by weight: 46-50 parts of diatomaceous earth, 10-12 parts of purified attapulgite, 3-5 parts of talcum powder, 14-16 parts of expanded corn starch, 5-8 parts of hydroxypropyl methyl cellulose, 1-3 parts of polyacrylamide and 5-7 parts of titanium dioxide. The preparation method comprises the following steps: S1. sequentially pouring the talcum powder, expanded corn starch and titanium dioxide into a stirrer to be mixed and stirred, and stirring for 5-10 minutes; S2. sequentially pouring the diatomaceous earth and the purified attapulgite into the mixture in the step S1, and stirring for 10-15 minutes; and S3. adding the polyacrylamide and hydroxypropyl methyl cellulose in the mixture in the step S2, stirring for 20-30 minutes, and then, sieving the mixture through a sieve of 250 meshes.