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The present invention provides novel compounds, compositions, and methods for the delivery of biologically active RNA molecules to cells. Specifically, the invention provides novel nucleic acid molecules, polypeptides, and RNA-protein complexes useful for the delivery of biologically active RNAs to cells and polynucleotides encoding the same. The invention also provides vectors for expressing said polynucleotides. In addition, the invention provides cells and compositions comprising the novel compounds and vectors, which can be used as transfection reagents. The invention further provides methods for producing said compounds, vectors, cells, and compositions. Additionally, vectors and methods for delivering biologically active RNA molecules to cells and / or tissues are provided. The novel compounds, vectors, cells, and compositions are useful, for example, in delivering biologically active RNA molecules to cells to modulate target gene expression in the diagnosis, prevention, amelioration, and / or treatment of diseases, disorders, or conditions in a subject or organism.

The invention relates to a method and system for synchronization of relational databases. The method for synchronization of the relational databases comprises the following steps of: creating a data synchronization task aiming at varied data among a plurality of databases; analyzing the data synchronization task; capturing varied data in an original database; and carrying out the data synchronization task according to schedules. In the technical scheme provided by the invention, a synchronization rule among the databases is created into a task to be carried out, a database agency is used for shielding heterogeneity among the databases, the varied data is captured through a trigger and a capture table, loopback write-in is avoided, and timing and / or multi-threading implementation of the data synchronization task is realized through a scheduler. The method and the system have the advantages of simplicity and easiness in use, flexibility and high efficiency.

A visual analyzing and predicting method based on a virtual geological model is finished by depending on an interactive visual tool. The method mainly comprises steps of searching a multi-dimensional geological data model from a database and a file system; arranging or resetting a virtual geological scene by setting or regulating corresponding parameters and models; regulating coordinate, scale, data format and the like, of the geological model; sending results of visual calculating, analyzing, predicting and searching into a dual-display cache region; and integrally displaying geological data in a visual platform at real time. The method meets requirements of earth science application, enhances representability of geological data, improves comprehension and application environment of geological data, converts logical thinking of geologists into a trial ground having an imagery thinking of time and space in a virtual environment, helps strengthen deep recognition to complex geological phenomena, uncovers deep information and internal relation in geological data, digs out and extract knowledge unable to be obtained in a traditional mode, improves utilization rate and geospatial analytics of information, and provides a brand-new method for geologists to observe, explain, analyze and imitate geological phenomena in a three-dimensional space, predict and know geospatial distribution of geological structure in a studied area through known data, and obtain mine position, mine reserves and other important information. Furthermore, the human-computer interactive tool is simple and easy to learn to operate, saves cost, reduces blindness in application, reduces risk, conducts and makes decision for production and environment analysis and has significant economic and social benefits.

Methods are described for analyzing access list subsumption in routing devices of a computer network and for identifying computer network integrity violations, by producing structured data that includes stored router names and access lists that include elements with address / mask pairs, or patterns used to filter data into and out of a routing device, respectively; determining whether access lists in the structured data include elements in which a first element in the access list has a more general or equal address / mask pair, or pattern, respectively, than a second or subsequent element, or pattern; and storing in electronic memory a report of elements or a list of patterns, respectively, in which a first element or pattern is more general than or equal to a second or subsequent element or pattern.

Methods are described for analyzing access list subsumption in routing devices of a computer network and for identifying computer network integrity violations, by producing structured data that includes stored router names and access lists that include elements with address / mask pairs, or patterns used to filter data into and out of a routing device, respectively; determining whether access lists in the structured data include elements in which a first element in the access list has a more general or equal address / mask pair, or pattern, respectively, than a second or subsequent element, or pattern; and storing in electronic memory a report of elements or a list of patterns, respectively, in which a first element or pattern is more general than or equal to a second or subsequent element or pattern.

The invention relates to a blood vessel computer aided iconography evaluating system. The system comprises the following contents: (A) transmission of CTA (Computed Tomography Angiography) from a CT (Computed Tomography) working station to a PC (Personal Computer), wherein a transmission way comprises network card connection, CD burning and CT film scanning; (B) CTA three-dimensional reconstruction, wherein a three-dimensional reconstruction method comprises shaded surface display (SSD), maximum intensity projection (MIP) and multiplane reformation (MPR), obtains various real and clear three-dimensional models and images and can be used for observing a blood vessel three-dimensional space structure anytime and anywhere and lay the foundation for the three-dimensional measurement of various blood vessel geometric parameters; (C) blood vessel structure three-dimensional measurement; and (D) aneurysm endovascular graft exclusion virtual graft. The invention provides the computer aided iconography evaluating system which is suitable for people to use at random and is more accurate. In addition, the invention plays a role in blood vessel surgical scientific research, teaching, surgery training, and the like. The system realized by the invention is stable and reliable and is suitable for being popularized and used in blood vessel surgery centers of various large, medium and small hospitals.

An information processing system includes a management device mounted on a vehicle, and a terminal device outside the vehicle. The management device performs as follows: obtaining as identification information of a user a user ID and a password from the terminal device; selecting, based on the identification information obtained, a display target of items and device information to be preferentially displayed on a display device of the terminal display; collecting device information corresponding to the display target from devices (e.g., door ECU) in the vehicle; and generating system information storing information relating to the items selected and the device information collected. The management device then causes, by sending the system information generated to the terminal device, the terminal device to hierarchically display the display target in a tree form on the display device of the terminal device.

The invention discloses an IndexR real-time data analyzing library. The IndexR real-time data analyzing library realizes a structure data format which can be arranged in a distribution environment, can be subjected to parallel processing, is provided with an index and is of a rank type. On the basis of the data format, a data warehouse system is built through the IndexR; mass data sets can be subjected to rapid statistical analysis (OLAP) on the basis of Hadoop ecology; the data can be imported in real time, moreover, the zero delay of querying is realized. The IndexR is deigned to solve the problems such as slow analyzing under a big data scene, data delay, and complex system. According to the IndexR real-time data analyzing library, the data is stored in HDFS; the Zookeeper is used for communicating and negotiating in the cluster; the Hive is used for conveniently managing partitioned data; the data can be rapidly imported in real time through Kafka; an outstanding distributive querying engine Apache Drill is used in a querying layer.

A battery pack is made up of a plurality of flat prismatic batteries arranged face to face, each battery having one electrode terminal protruding from one end face in the height direction of the battery case and this end face or a side face of the battery serving as the other electrode terminal. The connector for electrically connecting adjacent prismatic batteries includes a flat part that is welded to one electrode terminal of one prismatic battery of the adjacent prismatic batteries, and a cylindrical part that is fitted onto and welded to the other electrode terminal of the other prismatic battery. The cylindrical part is formed in an attachment part that extends from the flat part through an upright part in the direction in which the batteries are aligned. The connector enables reliable electrical connection of the prismatic batteries despite possible variation in height of the electrode terminals.

The invention discloses a high-temperature slag handling technology by the tilting roller process and a high-temperature slag handling device. The handling technology includes that high-temperature metallurgical slag is poured into a rotating working barrel body with a certain angle of inclination in the axial direction by a loading hopper; the slag in a front barrel body of the working barrel body is fast cooled by a cooling medium and the cooling water sprayed by a spray head in sequence and then crushed; the cooled and crushed slag particles are driven to drop from the gaps among cage bars and the gaps between the cage bars and a barrel body shoveling plate into a lower chamber filled with the cooling water to be cooled for the second time; along with the rotation of the working barrel body, the slag particles soaking in the cooling water in the lower chamber are carried to the upper part of the front barrel body by the barrel body shoveling plate provided with dewatering holes, poured into an open discharging chute and conveyed out of the device; the cooling water that carries fine slag particles and is separated by the barrel body shoveling plate flows to a rear barrel body, and the fine slag particles separated and intercepted by a netty slag-water separating device arranged on the rear barrel body are sent to the discharging chute and conveyed out of the device by a small shoveling plate arranged on the internal side surface of the rear barrel body.

The invention provides an ecological grass planting trench for cities with rich water resource, which is arranged on one side of a sidewalk road. The ecological grass planting trench sequentially comprises a vegetation layer, a planting soil layer, a building block brick layer, a water permeating and discharging pipe and a gravel layer from top to bottom. The ecological grass planting trench is arranged on one side of the sidewall road and used for collecting rainfall running water on the sidewall road, the pollutants in the running water can be reduced, and a purpose for locally purifying the running water and controlling the pollution of the running water can be achieved; the ecological grass planting trench is arranged between the sidewall road and a green land, so that not only is the landscape not influenced, but also convenience in construction can be realized; the rainfall running water is stopped in the gravel layer and gradually and slowly permeated, finally the water content of the soil of the green land is replenished, the rainfall running water can be completely absorbed and purified, and the water for irrigating the green land can be reduced; the lower end of the water permeating and discharging pipe is connected with a rainy water opening or a rainy water well, the other end of the water permeating and discharging pipe is closed, so that the collected rainfall running water on the sidewalk road can be collected into the rainy water opening or the rainy water well, and a purpose for reducing the rainfall running water and postponing the flood peak can be achieved.

The invention provides an improved intraoperation stent system, which comprises an external tube, an internal tube which is sleeved in the external tube and capable of moving relative to the external tube, a control guide wire which is positioned in the external tube and can be inserted and withdrawn and a membrane-coated stent positioned between the external tube and the internal tube, wherein an ejecting device is arranged on the internal tube and is positioned behind the membrane-coated stent in a guiding direction to push the membrane-coated stent. The shape of the intraoperation stent system is small, the flexibility of the intraoperation stent system is high, the intraoperation guiding is convenient and damage to blood vessels is avoided. In the intraoperation stent system, the external tube also has marks, so the positioning is easy, the need of re-imaging in operation is obviated, and the requirements of hybrid operation are well met.

A frame structure is provided for a motor vehicle having at least two longitudinal girders, each having a first longitudinal section and a second longitudinal section, which are at an angle to one another, so that in the installed state of the frame structure in a motor vehicle, the first longitudinal section lies essentially horizontally below a floor plate of the vehicle body and the second longitudinal section extends essentially upward and, viewed in the forward travel direction, the first longitudinal section is arranged behind the second longitudinal section. It is provided that beginning in the area of the transition from the second longitudinal section to the first longitudinal section or an area adjacent thereto, the longitudinal girders extend at least partially away from one another in the direction of the first longitudinal section. Furthermore, the invention relates to a rear frame structure and a vehicle body.

The embodiment of the invention discloses a data modification and synchronization method, apparatus and device and a storage medium of a block chain. The data modification method of the block chain isapplied to inspect the inspection node in the block chain network. The method comprises the following steps: the inspection node obtains at least one synchronization block from an ordinary node, andthe synchronization block is an ordinary block; The checking node checks the data of the synchronous block according to the set modification rules to determine the target modification data; The inspection node modifies the target modification data; The checking node generates a checkpoint according to the synchronization block, and calculates and generates a checkpoint mark according to the data of the synchronization block. The checking node associates the checkpoint identifier with the synchronization block for recording; The checking node confirms the checkpoint identification by the checking node in the checking block chain network for storing in the checking block. A synchronization block is used for synchronous downloading of a common node. Through the technical proposal provided bythe embodiment of the invention, harmful data can be removed from the block chain.

The invention discloses a leaf-cutting propagation method for succulent round-leaf Aeoniumarboreum. The leaf-cutting propagation method includes the following steps: 1, soil is prepared, wherein culturing soil comprises Akadama soil, bamboo charcoal, sphagna, vermiculite, peat soil, fermented rice hull coal, pelelith, active carbon and slow-release fertilizers; 2, round-leaf Aeoniumarboreum stock plants are irradiated by an ultraviolet lamp three times, wherein the duration of each time of irradiation ranges from 3 hours to 4 hours, and the three times of irradiation are carried out at one-day intervals; 3, leaves of the round-leaf Aeoniumarboreum stock plants in the step 2 are slightly broken off and placed at shady, cool and ventilating positions to be aired two to three days to enable fractures to be dried through airing; 4, the leaves dried through airing in the step 3 are placed on the culturing soil in the step 1 with the back faces of the leaves downward, the sides, provided with the fractures, of the leaves are slightly pressed with fingers to enable the leaves to be slant, and the fractures are tightly attached to the surface of the vermiculite; 5, after roots are grown from growing points at the fractures of the leaves, a layer of coarse gravel with the particle diameters ranging from 1 mm to 3 mm is scattered on the culturing soil. By means of the method, the leaf hydration probability is lower than 3%, and the survival rate of new plants can reach 97%.

The invention provides a suitcase pull bar capable of optionally adjusting the length. The suitcase pull bar comprises fixed rods, telescopic rods, a handle and a control assembly, wherein the telescopic rods can be telescopically arranged in inner cavities of the fixed rods in a sliding way; a gear rack is arranged on one side surface of each fixed rod; two gears are arranged on the lower end ofeach telescopic rod, the two gears are respectively matched with the gear racks, the two gears are arranged on two ends of a gear shaft, the middle part of the gear shaft is fixedly connected with aninstallation rod, and the installation rod is fixedly arranged in the corresponding telescopic rod; the control assembly comprises a button, transmission rods and locking blocks; the locking blocks are arranged on the gear shafts; the locking blocks are in clamping locking with tooth grooves of the gear racks; the transmission rods are arranged in the installation rods; a trigger block is arrangedon one end of each transmission rod; the other end of the each transmission rod is connected with the button; inclined surfaces in mutual fit are obtained between the trigger blocks and the locking blocks. According to the suitcase pull bar capable of optionally adjusting the height, provided by the invention, the pull bar length which is most comfortable for a user can be adjusted according to demands of the user.

The invention discloses a special mobile phone for the deaf-mute, which relates to a mobile phone. The invention uses an intelligible typed mobile as a carrier and is provided with an information input processing module (1), a voice application extension module (2), and an information feedback processing module (3); by using the information input processing module (1), the deaf-mute (4) can transmit a word message to a communicatee (5) in an outside world by sending short messages or transmitting into a voice; the voice or other feedback messages of the communicatee (5) can be transmitted to the deaf-mute (4) by the information feedback processing module (3) after being translated into corresponding words or diagrams; the voice application extension module (2) provides such functions as of an electronic listening and reading, a speech of the deaf-mute, and a help seeking alarm for the deaf-mute (4). The intention can solve a communication problem among the deaf-mutes, and in addition can solve hard communication between the deaf-mute and the sound.

The invention discloses an intelligent multi-core cable detection device and a detection method thereof. The detection device is composed of a PC, a main engine, a cable transfer box, and a connection cable. An Excel sheet for the known cable connection relationship is guided in the PC interface, and an N-row N-column 0 and 1 matrix is generated; a cable with a corresponding type is selected for testing, high level 1 is sequentially sent to one end of the tested cable for the first core to the Nth core, low level 0 is sent to the other positions, the other end of the cable combines the received result data into an N-row N-column result matrix, and by comparing the result matrix with the original matrix, the numbers of open circuit cores and short circuit cores of the cable are judged; and as for a cable with an unknown wire sequence, unknown cable testing is selected, the testing result generates an N-row N-column matrix, the matrix is generated reversely into an Excel cable relationship sheet to be stored in the data base, and automatic detection of the cable of the type next time is realized. The device and the method of the invention can complete automatic detection on a multi-core cable and a cable with an unknown wire sequence, and has the advantages of strong generality, high efficiency and low cost.

This invention provides a composition matter comprising rare earth-doped up-conversion nanoparticles (UCNPs) encapsulated with a silica shell. In one embodiment, a photosensitizer is incorporated into the silica shell. In another embodiment, the composition further comprises a targeting molecule. In still another embodiment, a small interfering RNA (siRNA) molecule is also attached to the silica shell with the targeting molecule. The invention further provides methods for synthesizing such compositions and for using them in therapeutic and diagnostic applications. These applications use infrared or near infrared activation to excite the UCNPs.

The invention relates to a sheet material feeding and conveying device. The sheet material feeding and conveying device comprises a rack which is located on the two sides of a conveying production line and provided with stand columns, a lifting machine base is arranged on the lower portion of the rack, a row of transmission rollers used for supporting stacked sheets is arranged on the machine base, sling chains are connected beside the front side and the rear side of the machine base respectively and used for driving the machine base to ascend and descend, the sling chains stride transmission chain wheels on the rack respectively, and a sling sinker used for balancing weight is arranged at the outer side end of each sling chain; the front transmission chain wheel and the rear transmission chain wheel on the same side are driven by a same stepping motor transmission mechanism; the front side and the rear side of the upper portion of the machine base are respectively provided with a lifting sucker used for adsorbing the sheets, the lifting sucker on the front side is connected with a transverse air cylinder connected to the rack so that the lifting sucker on the front side can be driven to move front and back in a reciprocating mode, the front side of the lifting sucker on the front side is provided with a pair of horizontal rollers used for drawing the sheets to move forward, and the output end of each horizontal roller is provided with a sheet conveying device. Not only is the sheet material feeding and conveying device beneficial for guiding a sheet bearing base from the production line, but also lifting control and transmission are convenient and accurate, and feeding is smooth.

The present invention relates to a cutter holding device which is provided with a cutter receiving part, especially a clamping disc, such as a thermal shrinking chuck, a nipper chuck, a hydraulic expanding chuck and a high-precision chuck. The handle of cutter, especially the handle of rotating cutter is accommodated in the cutter receiving part, wherein the cutter holding device comprises a pulling-out preventing fixing device which fixes the cutter and prevents the axial pulling-out. The pulling-out preventing device comprises at least one fixing component and at least one fixing groove which is corresponding with the fixing component and accommodates the fixing component. The fixing component cooperates with the fixing groove with a mode of forming locking. According to the invention, the fixing component and the fixing groove are all designed to at least partial sphere-head shaped. Preferably the cutter is provided with the locking groove. As the fixing groove is preferably spirally rotating along the cylindrical handle of cutter, the rotation direction is corresponding with the slotting direction of cutter, and axial fixing can be executed to the cutter. Thereby the cutter will not be axially pulled out from the cutter holding device in the running period. A component for exerting force is additionally installed. The component forms a gapless attachment on the pulling-out preventing fixing device after shrinking and installation.

The invention discloses a network public whiteboard system based on cloud computing, and the system comprises terminals and a network public whiteboard platform, wherein the terminals communicate with the network public whiteboard platform through a browser, the network public whiteboard platform further comprises a transmitting unit, a foreground U1 unit and a network public whiteboard processing unit, the foreground U1 unit at least comprises a display subunit and an interaction subunit, the display subunit is used for displaying the data in the browser of the terminals, and the interaction subunit is used for intercepting and capturing input operation on the browser of the terminals through a message hook and sending the input operation to the network public whiteboard processing unit through the transmitting unit; and the network public whiteboard processing unit is used for receiving operation data on the browser of the terminals, processing requests of different users, coordinating the parallel processing of the users, transmitting the processing result through the transmitting unit and displaying the processing result on the corresponding terminal browser through the foreground U1 unit.

The invention relates to a configuration method for a database of a communication device in a digital substation. The configuration method comprises the following steps: forming an independent middle text, namely, a rule file, according to an IEC61850 standard and a mapping rule for the database of the communication device; automatically generating data of a measuring point according to an engineering requirement and inputting the data of the measuring point into the database of the communication device, for an imported ICD (Interface Control Document) of the device during the configuration process of the communication device; and configuring through configuration software. According to the configuration method, the middle text is supplied to the database of the communication device and the database of the communication device is statically generated according to the corresponding rule in the middle text after the configuration software is imported into the ICD of an IEC61850 device, wherein the rule in the middle text comprises three parts: a basic classifying rule, a prior rule and a shielding rule. According to the configuration method, the database for the measuring point can be flexibly and automatically generated for the imported ICD of the device according to the engineering requirement, so that the process of manually selecting the point by an engineering configuring person is omitted, the possibility of configuration fault is eliminated and the efficiency of engineering configuration is increased.

Disclosed is a roll gap setting method of a wrapper roller in a recoiling machine. The method belongs to the technical field of control. A temperature measuring instrument is arranged at an inlet of a recoiling machine set. An initial roll gap set value static table is established in a host computer. According to characteristics of strip steel in different specifications, initial roll gap set values of different wrapper rollers are set. When the host computer receives a steel-biting signal, three initial roll gap set values of the wrapper roller are searched in the initial roll gap set value static table of the wrapper roller and then the three initial roll gap set values are downwardly sent to a recoiling basic automatic computer of the recoiling machine. According to an actual recoiling temperature, the recoiling basic automatic computer carries out a corresponding compensative correction to roll gap set values. Influences of factors such as a recoiling temperature, a width of the strip steel and a thickness of the strip steel on tightness degree of a rolling layer of an inner circle of a steel roll can be fully considered. All of the influences of the factors on the tightness degree of the rolling layer of the inner circle of the steel roll can be considered. Inner circles of various steel rolls are ensured to be compact and slipping accident of the recoiling machine can be effectively reduced. In addition, introduction of thick-specification stripe steel can be improved and steel-waste accident is reduced.

The invention relates to a large-screen visualization display system, in particular to a large-screen visualization display system and method based on procedural model configuration and belongs to the field of electric power information. The large-screen visualization display system based on procedural model configuration comprises a background procedure instantiation data interaction module, a procedure component assembly configuration module and a foreground effect display module, wherein the background procedure instantiation data interaction module, the procedure component assembly configuration module and the foreground effect display module are connected in sequence. By the adoption of the large-screen visualization display system and method based on procedural model configuration, configuration of similar workflow on a large screen is achieved, instantiation data of the procedure can be displayed, a user can flexibly conduct configuration on procedures in different scenes, assembly of procedure components can be conducted according to the drilling procedure, and procedure instantiation display can be conducted.

The present disclosure relates to a method and system for automated biomechanical analysis for bodily joints generally and in one use to anterior cruciate ligament (ACL) injury prevention and recovery. The disclosure includes processing an automated biometric analysis algorithm on a computer processor and recording measurements relating to a plurality of physical therapy tests. The disclosure tracks the movement of joints on the subject's body from the subject's trunk downward to the subject's toes and calculates the results of the physical therapy tests for analyzing angles, movement quality, and related interrelationships amongst said joints. The method and system further derive and provide reports of comparisons of results with normative values and associate indicators for the comparisons to the potential of the subject to experience biomechanical conditions of injury or development.