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Methods and compositions for treating ineffective erythropoiesis

InactiveUS20170327800A1Improve the level ofIncrease red blood cell and hemoglobin levelPeptide/protein ingredientsTransferasesIneffective erythropoiesisPrimate
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and / or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans.
Owner:ACCELERON PHARMA INC

Method for treating AIDS and HIV infection using select peptides from the beta subunit of human chorionic gonadotropin

The present invention relates to select peptides of the carboxy terminal and aminoterminal portion of the beta unit of hCG and pharmaceutically acceptable derivatives thereof that can be used for controlling retroviral, e.g., human immunodeficiency virus (BV infections. The invention comprises a method in vitro as well as in vivo for prevention and / or treatment of acquired immune deficiency syndrome (AIDS) at pharmacological doses of beta hCG-derived peptides and pharmaceutically acceptable derivatives thereof which are sufficient to exert an anti-HIV effect for a sufficient period of time.
Owner:METRATON
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