The invention discloses a GC-NCI-MS determination method for determining residual amount of chlorantraniliprole, which is mainly used for determining content of residual chlorantraniliprole in
complex matrix food agricultural products such as cereal grains and animal derived foods. The GC-NCI-MS determination method comprises the following steps: extracting the residual chlorantraniliprole in a sample by adopting
acetonitrile or
acetonitrile solution containing 1% of
acetic acid in a homogenizing manner; purifying and concentrating by adopting a C18 / PSA
solid phase extraction column, performing
gas chromatography-negative
chemical ionization-
mass spectrum (GC-NCI-MS) detection, establishing a correcting
standard curve by adopting a blank
matrix solution which does not contain pesticides, and quantifying by adopting an external standard method. With the adoption of the GC-NCI-MS determination method, the average
recovery rate is 86.8%-96.9%, the average
relative standard deviation (RSD) is 4.0-9.7%, the
detection limit is 1.41 microg / kg; the GC-NCI-MS determination method has the advantages of simplicity and convenience in operation, rapidness, good
impurity removal effect, high sensitivity, strong characteristic
feather, good
repeatability, and accuracy in qualitative and quantitative effect; the 0.01mg / kg residual limit for corresponding
food safety detection by countries including America, Japan, European Union and Canada, namely, the technical requirement of uniform limit, is met, and therefore, powerful
technical support is provided for guaranteeing
food safety of Chinese people and healthy development of export trade.