The invention discloses a compounded insecticidal suspension emulsion with chlorpyrifos and spirotetramat and a preparation method of the compounded insecticidal suspension emulsion. The compounded insecticidal suspension emulsion comprises the following contents in percentage by weight: 2-30% of spirotetramat, 10-40% of chlorpyrifos, 5-20% of organic solvent and the balance water, and is formed by adopting the following steps of mechanical stirring, sanding and high-speed homogeneity cutting. The compounded insecticidal suspension emulsion has a stable property and a high medicine effect, and can be used for preventing injurious insects such as scale insects of oranges, cotton and apples, bemisia tabaci of vegetables, and the like. According to the invention, the compounded insecticidal suspension emulsion has the advantages that the water is used as the main dispersion medium, the pollution to the environment is small, the situations of oil deposition, sediment and the like when the compounded insecticidal suspension emulsion is stored for two years under normal temperature are not existed, the service life of a storage rack is long and is non-flammable, the storage and the transportation is safe, compared with using the spirotetramat alone, the cost is low, and the like.