The invention relates to hygienic insecticidal granules and a preparation method thereof. The hygienic insecticidal granules are prepared from the following components in parts by weight: 0.1 to 10% of an active component A, 0.1 to 40% of an active component B, 0.2 to 20% of a solvent, 0.1 to 5.0% of an emulsifier, 0.1 to 5.0% of a dispersant, 0.1 to 5.0% of a slow-release film forming agent, 0.1 to 5.0% of a fast-release film forming agent, 0.1 to 10% of an adsorbent, and the balance of a porous carrier. The active component A is a slow-acting reagent, namely Bacillus thuringrensis israelesis Bti or pyriproxyfen; the active component B is selected from the group of fast-acting type neurotoxic reagents, namely fenthion, temephos, chlorpyrifos, pirimiphos-methyl, abamectin, ivermectin, and emamectin benzoate; the active component A is used for being adsorbed into the porous carrier which is wrapped with the active component B; the slow-release film forming agent is a hydrophobic high molecular polymer; the fast-release film forming agent is a water-soluble high-molecular polymer. The specific slow-release film forming agent and the fast-release film forming agent are selected, especially, the composite slow-release film forming agent, the composite fast-release film forming agent and corresponding insecticidal active components which are further compounded in a specific ratio are good in compatibility and have better fast-release and slow-release effects.