131results about How to "Avoid dysfunction" patented technology

An apparatus for treating heart failure, including a conduit positioned in a hole in the atrial septum of the heart, to allow flow from the left atrium into the right atrium. The conduit is fitted with one or more emboli barriers or one-way valve members, to prevent thrombi or emboli from crossing into the left side circulation.

The present invention comprises a method of protecting organs or tissue susceptible to reperfusion-induced dysfunction after ischemia. The method comprises parenterally administering to a patient a therapeutical composition containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or a mixture thereof. Alternatively, organ or tissue transplants can be contacted with natural alpha-1 acid glycoprotein, natural alpha-antitrypsin or mixtures by perfusing or flushing them with a solution containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or mixtures thereof in a concentration of 0.1 to 5 g/l.

An ultrasonic probe is provided with a CMUT chip having a plurality of transducer elements that change electromechanical coupling coefficients or sensitivities in accordance with a bias voltage to transmit and receive ultrasonic waves, an electric conducting layer formed on the ultrasonic irradiation side of the CMUT chip, an acoustic lens arranged on the ultrasonic irradiation side of the CMUT chip, an insulating layer formed in the direction opposite to the ultrasonic irradiation side of the acoustic lens, a housing unit that stores the CMUT chip in which the electric conducting layer and the insulating layer are fixed with an adhesive and the acoustic lens, wherein the insulating layer is formed by the material that includes at least either silicon oxide or paraxylene to prevent a solvent of the adhesive from soaking into the adhered portion.

A gait management apparatus applies stimulation to a user suffering from a neurological disease (such as Parkinson's Disease) gait dysfunction. Motion sensors are arranged to be worn by a patient, and electrical stimulation electrodes are on the legs for stimulation. A controller receives motion sensing signals, and processes these signals to generate stimulation signals for operation of the electrodes to stimulate limb movement upon detection of a gait abnormality. There may be a user actuator for user actuation of electrical stimulation, and the inputs may be a series of taps. The controller may provide signals to prevent occurrence of freezing of gait when it senses that a patient is walking or has an intention to walk. Also, it may apply stimulation at an intensity level which is insufficient for functional muscle stimulation but sufficiently high to trigger activation of efferent nerves.

An embodiment of the invention provides a proximity sensor calibration method and device, a mobile terminal and a computer readable medium and belongs to the technical field of mobile communication. The method includes: when the starting of the proximity sensor is detected, acquiring the proximity value collected by the proximity sensor according to preset calibration parameters; judging whether the proximity value is larger than a preset standard value and smaller than a preset maximum threshold; if so, updating the preset calibration parameters according to the difference between the proximity value and the preset standard value. The method has the advantages that the preset calibration parameters are updated according to the difference between the proximity value and the preset standardvalue, so that the proximity value collected by the proximity sensor according to the updated preset calibration parameters is closer to the preset standard value, and the measuring accuracy rate ofthe proximity tactile sensor is increased.

A catheter for blood removal that is to be provided in the coronary sinus via the inferior vena cava to remove the blood in the coronary sinus from the body wherein: the catheter for blood removal has a straight back end shaft, a curved front end shaft connected in the front end side of the back end shaft, a hub connected in the back end side of the back end shaft and a blood removal lumen extending from the back end of the catheter for blood removal to the front end thereof; the front end shaft comprises a first straight part, a first curve part following the first straight part, a second curve part following the first curve part, a second straight part following the second curve part, a third curve part following the second straight part and a third curve part following the third straight part.

This invention is directed toward herbal compositions and methods of treatment for prevention or treatment of erectile dysfunction disorders and ameliorating symptoms thereof and as a preventative measure against erectile dysfunction. The methods comprise administering a therapeutically effective composition of matter comprising the following herbal and other components: Herba cynomorii, Rhizhomnas atractylodis macrocephalae, Radix rehmannia glutinosea longui, Herba epimedii, Fructus lycii, Fructus schisandrae chinensis, Radix poloygoni multiflor, Cortex cinnamonia cassiae, Fructus amoni, and Radix ginseng. The components of the invention interact synergistically once consumed to remedy or prevent erectile dysfunction when taken as prescribed. The invention is completely herbal in composition and does not contain any hormones, morphine, or any of the compositions of matter know by trade names Viagra, Cialis, Sildenafil or Vardenafil. Side benefits of taking this dietary supplement include increased energy, improved immune system strength, and improved erectile activity in men without erectile dysfunction.

The invention discloses a method for preparing a propolis, bee pollen and royal jelly nutritive mixture, which is characterized by comprising the following steps: adding high-purity propolis into 75 percent alcohol for heating and melting to prepare propolis liquid; mixing and stirring the propolis liquid and broken wall bee pollen uniformly, putting the mixture into a 50 DEG C low blowing dry box for full drying, taking the mixture out, mixing the mixture with freeze-dried powder of royal jelly, grinding the mixture into fine powder with 200 meshes by a fluid jet mill and packaging the fine powder. The method has the advantages of solving the difficult problems of difficult decomposition of the propolis, sterilization of the bee pollen and no high-temperature resistance of the royal jelly, simultaneously obtaining the nutrition and health care functions of three bee products, improving the absorptivity of the propolis, preventing nutrition of the three natural bee products from being damaged, having good synergism on the medical care function of the mixture of the three, and even improving the efficacy by 3 to 5 times. The preparation method is scientific, simple and convenient, and has low cost, and safety and reliability; and the mixture is convenient to take.

The invention includes a compound of formula I:

wherein R₁, Y, A, n, R₄ and Z have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of PDE4 function and are useful for improving cognitive function and/or treating cognitive disorders or impairment, traumatic and/or ischemic injuries of the central and peripheral nervous system and/or psychiatric disorders in animals, especially humans.

The invention discloses a charging metering method for a charging station. A charging metering system of the charging station comprises a main processor, a power supply module, a display module, a communication module, an electric energy metering module, a data read-write module, a data storage module, an output module, an output port, a door lock and charging control module and a charging door, wherein the power supply module, the display module, the communication module, the electric energy metering module, the data read-write module, the data storage module, the output module, the output port and the door lock and charging control module are electrically connected with the main processor, and the charging door is controlled to be opened or closed by the door lock and charging control module. The charging metering method has the advantages that the modular design is adopted, and the coupling degree among all functions is reduced; the man-machine interaction practicability and the humanized use experience of the charging metering system are enhanced through the output port, and the reserved expansion space is provided for the system, and the function expansion of the hardwire can be carried out; the high-integration degree and the intelligentization of the system are realized through the automatic updating and the maintenance function of the system; and each function is realized in different stages, the stages are divided according to the function requirement, the phased implementation is carried out according to the importance program, and the function repetition or the function turbulence caused by the mutual influence because of the simultaneous communication among the modules is avoided.

The invention discloses a flexible display, a manufacturing method thereof and a piece of electronic equipment. The flexible display comprises a flexible display screen, a driving chip and a supporting device, wherein the flexible display screen comprises a flexible substrate that comprises a display area and a binding area; the driving chip is bound to the binding area; the supporting device covers the flexible substrate, and the supporting device located at the position of the binding area is provided with an opening. As the supporting device covers the entire flexible substrate, the flexible display and the manufacturing method thereof and the electronic equipment disclosed by the invention increase the strength of the bonding region, prevent the problem of poor function of the flexiblescreen body caused by that the signal lines are broken during peeling, reduce the attachment process of the support film, and make the flexible display thinner at the same time.

The use of 1-alpha-fluoro-25-hydroxy-16,23E-diene-26,27-bishomo-20-epi-cholecalciferol, or a pharmaceutically acceptable salt or ester thereof, for the manufacture of a medicament for the prevention and/or treatment of benign prostatic hyperplasia (BPH) and associated symptoms.

The present invention relates to methods of treating Alzheimer's Disease which utilize agents that increase neuronal phosphotidylinositol 4,5-biphosphate (PIP2), and to differentiated stem cell-based assay systems that may be used to identify agents that modulate phosphoinositide levels and thereby treat a variety of diseases. It is based, at least in part, on the discovery that edelfosine, an agent that increases PIP2 levels by inhibiting an enzyme that catalyzes PIP2 breakdown, decreases levels of neurotoxic A&bgr;42 peptide, particularly in cells expressing a mutant presenilin gene associated with Familial Alzheimer's Disease.

A Chinese medicine for treating the trauma of animal is prepared from primary medicine, secondary medicine and matrix in the ratio of (15-20%): (3-4.4%) and (75.6-82%).

The invention provides methods for modulating, e.g., antagonizing, the activity of the Hedgehog signaling pathway, and for treating Hedgehog related disorders such as cancers (e.g., medulloblastoma). In particular, the invention provides methods for inhibiting aberrant growth states resulting from phenotypes such as Ptch loss-of-function, Hedgehog gain-of-function, smoothened gain-of-function or Gli gain-of-function by administering to a mammal combinations of Smoothened inhibitors (e.g., a compound of Formula I, Formula II, or Formula III, or any of the compounds listed herein or incorporated by reference) and cholesterol biosynthesis pathway inhibitors (e.g., statins), Gli inhibitors, and/or Phosphatidylinositol 3-kinase (PI3K) inhibitors.

A method for protection of a mammal that has impaired glucose tolerance or early stage diabetes mellitus from developing overt or insulin dependent diabetes comprises administering an orally effective dose of a pharmaceutical formulation comprising insulin at nighttime, e.g., at or shortly before bedtime.