44 results about "Viscoelastic Substances" patented technology

A plunger for an IOL injector device includes a shaft with a distal tip and a compressible sleeve positioned about the shaft with the tip extending forwardly of the sleeve. In a first stage of IOL advancement through the injector device, the plunger tip engages and pushes the IOL through a first section of the injector body. In a second stage of IOL advancement, the sleeve enters the narrowing section of the injector body toward the open tip thereof with the IOL and sleeve both undergoing compression. The sleeve compresses and lengthens in a forward direction ultimately enveloping the plunger distal tip. Viscoelastic applied inside the injector accumulates between the leading edge of the compressed sleeve and the compressed IOL thereby creating hydraulic pressure which pushes the compressed IOL through the remainder of the injector body and out the open distal tip thereof.

An improved viscoelastic composition useful in the performance of ophthalmic surgical procedures and especially cataract procedures is disclosed. The embodiments of the composition comprise combinations of sodium hyaluronate and chondroitin sulfate and exhibit an improved rheological profile.

The invention discloses a device for preparing composite viscoelastic substances. The device comprises a tank. The tank is a cube, first hydraulic rods are arranged in the middles of six inner side surfaces of the tank and are perpendicular to the corresponding inner side surfaces of the tank, the ends of fixed rods of the first hydraulic rods are fixedly connected with the inside of the tank, a hollow sphere is arranged between the inner ends of the six first hydraulic rods, two perpendicular annular grooves are formed in each outer side surface of the hollow sphere and include a horizontal annular groove and a perpendicular annular groove, power sleeves are fixedly mounted at the ends of movable rods of the first hydraulic rods and are coaxial with the center lines of the corresponding first hydraulic rods, the inner ends of the power sleeves deeply extend into the corresponding annular grooves, and power wheels are mounted at the inner ends of the power sleeve and can be matched with the inner bottom surfaces of the corresponding annular grooves in a contact manner. The device has the advantages that the composite viscoelastic substances can be blended at first proportions, canbe comprehensively stirred and can be automatically accommodated, and accordingly procedures for preparing the composite viscoelastic substances are simple and are high in efficiency.

The problem of the present invention is to provide a method of efficiently producing therapeutic alternative corneal endothelial cells, particularly, a method capable of stably producing them in a condition suitable for intraocular transplantation (in the anterior chamber) in a large amount. Furthermore, the present invention aims to provide a composition for transplantation, which is preferable for intraocular administration, particularly, into the anterior chamber. A therapeutic alternative corneal endothelial cell sphere can be produced by culturing stem cells in suspension in a differentiation induction medium containing a GSK3 inhibitor, retinoic acid and a ROCK inhibitor. Addition of a viscoelastic substance during intraocular (into the anterior chamber) transplantation of the sphere or cultured corneal endothelial cells dispersed into single cells can increase the number of adherent cells after transplantation.

A fluorescent viscoelastic agent for eye operation is prepared from a fluorescent substance and a non-fluorescent viscoelastic substance through physical and / or chemical mixing. It may have one color or the mixture of more colors chosen from white, red, blue, yellow, green, purple, and orange. It can improve the contrast and stereo feeling in visional field of doctor.