The invention provides a design method for large-scale multiple-node server cabinets. A server cabinet, a calculation node slot, a 3+1 power module slot, a gigabit switch extended reserved slot, a network cable guiding slot, a 3+1 power module slot, a gigabit exchange data network module slot, a RMC (rational method composer) module slot, a gigabit exchange management network slot, a reserved power module functional extended slot, a reserved power module functional extended slot, a hot-plug fan module, a device interface back board and a power strip are assembled into a large-scale multiple-node server; and a server mainboard, a hard disk drive, an internal memory, and basic CPU( central processing unit) components are assembled into a fundamental node unit of the multiple-node server inside each server node. In addition, the server cabinets have the function of concentrated power supply and concentrated heat dissipation, so that the functions of unified racking, rapid arrangement and concentrated management of the multiple nodes can be realized, the operation and maintenance can be simplified, and the space utilization rate of each entire cabinet is increased by 20%.