The invention provides a grafting breeding method of paeonia delavayi, and belongs to the technical field of grafting. The method comprises the steps of rootstock cultivation, rootstock preparation, scion preparation, grafting, sand bed preparation, sand storage, sand storage management, transplanting and post-transplant management; wherein the rootstock is selected from peony roots in a 3-5 yearold growing period or roots of paeonia ostii seedlings in a 2-3 year old growing period, the root length of the selected rootstock is 20cm-25cm, and the root diameter is 1.6cm-2cm; the scion is selected from paeonia delavayi branches growing in the same year, the length of the scion is 5cm-12cm, the diameter of the scion is 1.6cm-2cm, and the scion is required to have 2-3 disease-pest-free full buds; when sand storage is conducted, the grafted seedlings are bundled in bundles of 10 plants, and erected on the sand bed, and the periphery of each bundle of the grafted seedlings is filled with river sand to completely bury the grafted seedlings. The operation is simple, the breeding efficiency is high, the grafting cycle is short, the transplanting survival rate is high, the growth is strong,and the grafting costs are low.