115 results about "Muscle protein" patented technology

Methods for making dry protein powder or aqueous functional protein suspension compositions which provide increased moisture content and moisture retention in meats and other animal muscle tissue-based products have been developed. An important aspect is the use of alkali rather than an acid or a series of acid and alkaline treatments to dissolve the protein in the starting material. This includes both muscle and connective tissue proteins and fats, yielding a product in higher yield than acid based and other processes in which fat and connective tissue is removed and then only the remaining muscle dissolved in the acid. The connective tissue and fat increases water retention in meat into which it is injected, as compared to meat extracts containing only muscle proteins.

A meat or fish composition which retains moisture during cooking is provided. A concentrated aqueous acidic protein solution derived from animal muscle tissue is added to the meat or fish prior to cooking. The concentrated aqueous acidic protein solution comprises myofibrillar proteins and sarcoplasmic proteins substantially free of myofibrils and sarcomeres.

This invention provides: 1) a method of treating a subject suffering from a muscle wasting disorder; 2) a method of preventing a muscle wasting disorder in a subject; 3) a method of treating, preventing, suppressing, inhibiting or reducing muscle loss in a subject suffering from a muscle wasting disorder; 4) a method of treating, preventing, inhibiting, reducing or suppressing muscle wasting in a subject suffering from a muscle wasting disorder; and / or 5) a method of treating, preventing, inhibiting, reducing or suppressing muscle protein catabolism in a subject suffering from a muscle wasting disorder, by administering to the subject a selective androgen receptor modulator (SARM) and / or an analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, prodrug, polymorph, impurity or crystal of said SARM compound, or any combination thereof.

The present invention relates to increasing the athletic performance of humans using acteoside. This may be in the form of a pure compound, or plant extracts containing at least 10% acteoside by weight. Application of this invention provides increased strength, muscle power, endurance, muscle protein content, and reduced fatigue.

This invention provides: 1) a method of treating a subject suffering from a muscle wasting disorder; 2) a method of preventing a muscle wasting disorder in a subject; 3) a method of treating, preventing, suppressing, inhibiting or reducing muscle loss in a subject suffering from a muscle wasting disorder; 4) a method of treating, preventing, inhibiting, reducing or suppressing muscle wasting in a subject suffering from a muscle wasting disorder; and / or 5) a method of treating, preventing, inhibiting, reducing or suppressing muscle protein catabolism in a subject suffering from a muscle wasting disorder, by administering to the subject a selective androgen receptor modulator (SARM) and / or an analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, prodrug, polymorph, impurity or crystal of said SARM compound, or any combination thereof.

Moisture is retained in cooked or thawed food by adding to the food an aqueous suspension of animal muscle protein obtained from animal muscle tissue. The aqueous suspension is obtained by mixing comminuted animal muscle tissue with a food grade base to form an aqueous basic solution of animal muscle protein. The basic solution is mixed with a food grade acid to precipitate the protein in an aqueous composition. The precipitated protein then is comminuted to form an aqueous suspension of comminuted animal muscle protein.

The present invention relates to the use of a low-caloric high-protein nutritional composition for use in the prevention or treatment of a disease or condition in a mammal, which involves muscle decline, as well as to specific low-caloric high-protein nutritional compositions for stimulating muscle protein synthesis in a mammal. In particular, the invention relates to the use of a nutritional composition comprising per 100 kcal: (i) at least about 12 g of proteinaceous matter which comprises at least about 80 weight % of whey protein, relative to the total proteinaceous matter, and which comprises at least about 11 weight % of leucine, relative to the total proteinaceous matter, of which at least about 20 weight % is in a free form, relative to the total leucine, (ii) a source of fat and a source of digestible carbohydrates, for the prevention or treatment of a disease or condition which involves muscle decline in a mammal, especially an elderly mammal, wherein the nutritional composition is administered as 1 to 2 servings daily, each serving comprising between 80 and 200 kcal.

The present invention encompasses combination comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and / or muscle function.

The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or nutritional composition for the prevention and / or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal.

The present invention provides a full-nutrient food formula containing short peptides for populations with muscle attenuation syndromes. The formula food with a special medical use is prepared from the food-derived short peptides as a main raw material, contains concentrate extracts of traditional medibly and edibly homogenous Chinese herbal medicines of coix seeds, semen ziziphi spinosae, mulberries, apricot kernels, white hyacinth beans, licorice, etc., and then combines calcium beta-hydroxy-beta-methylbutyrate, creatine, oligosaccharides, various vitamins and minerals to form the compound formula. The formula can be used to prepare powdery or granular or liquid food. The food prepared according to the formula can provide high-quality proteins, vitamins and minerals required for the populations with the muscle attenuation syndromes in time, does not increase liver and kidney burdens, and at the same time, can significantly increase muscle strength and LBM, increase protein synthesis,prevent muscle loss and atrophy, inhibit muscle protein degradation, and protect muscle tissues. The provided formula food containing the short peptides with the special medical use is suitable for the populations with the muscle attenuation syndromes.

A low cholesterol protein composition derived from animal muscle tissue is provided. The low cholesterol protein composition is added to meat or fish prior to cooking to retain moisture during cooking in the fish or meat.

The invention provides a Chinese herbal medicine fodder additive for accelerating crucians to grow and enhancing the immunity and a fodder containing the additive. The Chinese herbal medicine fodder additive is formed by drying malts, hawthorns, green teas, lotus leaves, radix ophiopogonis and semen cassiae, and then performing crushing and uniform mixing. The Chinese herbal medicine fodder additive is added into a common crucian fodder so that the growing speed of the crucians can be obviously improved, the water content of muscles is reduced, the protein content of the muscles is improved and the fat content of the muscles is reduced; the hepatosomatic index can be reduced, and the spleen index and the head-kidney index can be improved; the blood serum T-SOD (Total-Superoxide Dismutase)can be obviously improved and the content of MDA (Malondialdehyde), TG (Triglyceride) and TC (cholesterol) is obviously reduced; the Chinese herbal medicine fodder additive has the characteristics ofgreenness, naturalness, no drug resistance, no residues, diversified functions, consideration of growth and disease resistance and the like; and the Chinese herbal medicine fodder additive can greatly reduce the breeding cost of the crucians and is suitable for industrial production.

Moisture is retained in cooked or thawed food by adding to the food an aqueous suspension of animal muscle protein obtained from animal muscle tissue. The aqueous suspension is obtained by mixing comminuted animal muscle tissue with a food grade acid to form an aqueous acidic solution of animal muscle protein. The acidic solution is mixed with a food grade base to precipitate the protein in an aqueous composition. The precipitated protein then is comminuted to form an aqueous suspension of comminuted animal muscle protein.

The present invention provides a protein deamidating enzyme that is added to a food material containing muscle protein and acts on the same to produce high-quality foods.

The present invention provides methods and compositions for the treatment of diseases associated with aberrant microsatellite expansions. Methods of the present invention comprise the use of recombinant adeno-associated virus vectors containing a transgene encoding at least one muscleblind protein. The present invention also provides an animal model for a disease associated with aberrant microsatellite expansion.

A water soluble peptide composition derived from animal muscle tissue proteins is provided. The peptide composition contains less than about 1 weight percent fats and oils based upon the weight of the peptide composition and less than about 2 weight percent ash based on the weight of the peptide composition.

The invention relates to a sterilized liquid or semi-solid acid enteral composition comprising per 100 ml 9 to 20 g of non-hydrolysed globular proteins, fat and at least 100 mg of divalent metal cations and having a pH ranging between 3 and 5. The invention further relates to a method for preparing a composition according to the invention, comprising a step wherein at least the non-hydrolysed globular proteins are subjected to a direct steam injection (DSI) at specific holding values, such as a holding temperature of 100 to 140° C. during a holding time of about 0.5 to 10 seconds, followed by a homogenization step and a sterilization step The composition according to the invention has a reduced astringency and can be used for medical purposes, such as for stimulating muscle protein synthesis in a mammal, in particular for treating sarcopenia, and for specific groups of people, such as elderly and sportsman.

The invention provides nutritive formula powder suitable for increasing muscles of old people and a preparation method of the nutritive formula powder. The nutritive formula powder comprises the efficacy components of nonfat dry milk powder, protein powder, calcium beta-hydroxy-beta-methyl-butyrate, sunflower oil powder, glucose syrup powder, fine white granulated sugar / cane sugar, fructo-oligosaccharide, galactooligosaccharide, a grape seed extract, a cucumber seed extract, a vitamin premix, a trace element premix, and a mineral premix. The nutritive formula powder is obtained in a mixing manner, particularly the calcium beta-hydroxy-beta-methyl-butyrate is added, and the components are in synergism, so that nutrient requirements of the old people can be met, concentration of amino acidsnecessary for blood is increased, the synthesis of muscle protein is stimulated, the net synthesis level of the protein of the old people is increased, the nutrient requirements of crowds with sarcopenia are met, and the nutritive formula powder can treat or prevent sarcopenia.

The invention belongs to the technical field of polymer-skeleton adhesion, and relates to a polymer-skeleton interface enhancing agent simulating mussel foot adhesion and a preparing method thereof. The polymer-skeleton interface enhancing agent is prepared from, by mass, 100 parts of polar polymers, 0.05-50 parts of nano filler, 0.01-10 parts of amine compounds, 0.01-10 parts of polyphenols and 0.01-10 parts of polyvalent metal salts. Based on an adhesion mechanism of mussel feet, by replacing expensive dopamine with the cheap and commercial polyphenols, the amine compounds and the polyvalentmetal salts, an adhesion enhancing system of imitative mussel foot muscle protein is constructed, and the polymer-skeleton interface adhesion strength is improved.

The invention discloses a low salt pickling and artificial fermentation process of Xuanwei ham, the technical proposal includes four steps of raw material selection, low salt pickling, fermentation fungi group cultivation and artificial fermentation, and a fermentation fungi group comprises Penicillium, lactic acid bacteria, Bacterium lacticum and Micrococcus in the ratio of 2.7:0.73:0.2:1. The advantages are that after raw material meat is inoculated with the lactic acid bacteria, the lactic acid bacteria uses carbohydrates such as glucose for fermentation to produce lactic acid, gelatinous tissues are formed by degeneration of muscle proteins under acidic conditions, bonding force among meat blocks is increased, and hardness and elasticity of meat products are improved, the lactic acid bacteria has high salt tolerance, can be used for fermentation of sugar to produce the lactic acid to play antibacterial and hypoglycemic effects and improve meat freshness; the Micrococcus has effects of decomposition of proteins and fat and reduction of nitrates, large amounts of amino acids are produced after the proteins are broken down, the amino acids are sources of a fresh taste, meanwhile by reduction of the cancerogenic substance nitrates, health of food customers can be protected.

The invention discloses a culturing method for promoting the growth and / or improving the nutrient composition of the hologynic tilapia, and belongs to the filed of aquaculture science and the field of physiological ecology of aquatic animals. According to the method, the tilapia is stimulated by running water to take countercurrent exercise, and the optimum exercise-intensity and exercise-time combinations including the high-intensity and long-time combination, the high-intensity and short-time combination, the low-intensity and long-time combination and the like are designed to culture the tilapia intermittently by running water. Compared with the existing culturing method, the culturing method disclosed by the invention has the advantages of improving the growth rate of the tilapia significantly, increasing the content of protein in the muscle of the tilapia, reducing the content of fat in the liver of the tilapia and preventing the tilapia from having a fatty liver.

Compositions and methods for administering a diet supplement to humans are provided for the enhancement of weight loss, suppression of appetite, prevention of muscle protein catabolism, and providing antioxidants in either a daytime or nighttime formulation. Said diet supplement is comprised of at least a source of Catechins and at least 3% Corosolic Acid. The diet supplement is provided in either daytime or nighttime formulations.

The invention relates to the technical field of food additives, in particular to a meat product adhesive and an application thereof in the processing respect of meat products. The adhesive consists of the following raw materials: 30-40% of glutamine transaminase, 30-40% of vegetable protein and 20-40% of methycellulose, wherein the vegetable protein consists of the following raw materials: 19-20.2% of isolated soy protein, 19-20.2% of vital wheat gluten, 23-25% of water-soluble wheat gluten and 35-39% of corn protein. The glutamine transaminase and the protein molecules form a cross linked structure so as to adhere chopped meat, and then the vegetable protein and the methycellulose are compounded as a gelling agent component, so that the adhesion intensity and the adhesion stability of the adhesive are improved, and the meat products can still maintain good integarity in the heat processing courses of frying, deep-frying, boiling, cooking and the like. The adhesiveness of the adhesive is improved, besides, the organizational structure and the emulsifiability of the meat products are improved, the integrity of muscle proteins is maintained, and the mouth feel of the entire meat products is improved.

The invention belongs to the technical field of breeding, and discloses a composition of guanidinoacetic acid and a synergist thereof, a preparation method and application. The composition of the guanidinoacetic acid and the synergist thereof is prepared by uniformly mixing guanidinoacetic acid, carbohydrates, sodium chloride and methyl donor, and can be added to daily ration for feeding animals.The guanidinoacetic acid and the methyl donor are added to promote creatine synthesis, and carbohydrates and sodium chloride are supplemented to increase creatine absorption of muscle tissues, so thatmuscle protein deposition is promoted, and the problem that the production performance of livestock and poultry is reduced under an antibiotic-free condition is solved. The composition of the guanidinoacetic acid and the synergist thereof is suitable for being added into daily ration to feed animals.

The invention discloses a method for preparing antioxidant polypeptide by solid fermentation of acanthogobius hasta muscle protein by aspergillus oryzae and belongs to the crossed field of aquatic product processing and microbial biotechnology. In the method, acanthogobius hasta muscle is used as a raw material, fresh fish muscle is homogenized in a homogenizer, the fresh fish muscle is subjected to heat preservation in a water bath at 80 DEG C, 8,000 grams of fresh fish muscle is centrifuged at 10 DEG C for 20 minutes, top grease is removed, and the rest materials is dried at 80 DEG C. A dry sample is uniformly mixed with vermiculite, the water content and pH value are regulated, and the aspergillus oryzae is inoculated for solid fermentation. After the fermentation is finished, the fermented product is added with distilled water, stirred and filtered, and the filtrate is concentrated to obtain the muscle polypeptide. The polypeptide prepared by the acanthogobius hasta muscle protein has high antioxidant function. When the method is used, the process parameter design is reasonable, the operability is high, the need of using finished protease is obviated, the cost is low, acanthogobius hasta resource can be fully utilized, and high potential economic effect is achieved.

The invention discloses a compound premix capable of enhancing the content of proteins in muscles of a grass carp. The compound premix consists of 10000g of the raw materials in weight mixing ratio: 1000g of compound vitamins, 5000g of compound mineral elements, 1000g of Beta-dextran premix agents, 500 to 1000g of taurine and unite bran. The addition of the compound premix of the invention in the formula feed for grass carp takes a weight proportion of 1 percent to ensure that the condition factor of the cultivated grass carp is larger than 2, the organ body weight proportion is smaller than the weight ratio, 11percent, and the content of the proteins in the muscles of the fish body is larger than 22 percent. The invention has the advantages that the grass carp cultivated using the compound feed of the premix has enhanced the edible part and the better meat quality. Saving the resources, the compound premix of the invention is beneficial to the environmental protection and is more beneficial to the increasing demand by the national citizens for the quality and safety of the aquatic foods.

A low salt protein solution not capable of forming a gel is obtained from animal muscle tissue by forming an aqueous acidic protein solution which is filtered to remove salt and acid. The low salt protein solution can be formed into a gel by adding a physiologically acceptable salt to the low salt protein solution and heating the resultant protein solution with added salt.

A muscle protein purifying method adjusts the concentrations of KCl, ATP and ammonium sulfate (A.S.) through the influences of different solution mediums on separation and purification and analyzes the dissociation and precipitation law of all fibrillin components and determines the separation and purification conditions of actin, myoballs and paramyosin with the ATPase activity as the protein denaturation indicating parameter. The method has the advantages that compared with a traditional protein purifying method, the novel method is low in purified protein denaturation degree and simple in purifying process, the actin, myoballs and paramyosin in smooth muscles of aquatic invertebrates are efficiently obtained through purification, and the purifying cost is saved to the maximum extent.