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Nutritional composition for the stimulation of muscle protein synthesis

A nutritional composition and stimulant technology, which is applied in the direction of drug combination, muscular system diseases, and the function of food ingredients, etc., can solve the problems of undisclosed use of anabolic amino acid derivative stimulants and vitamin D

Active Publication Date: 2013-05-01
NUTRICIA
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Problems solved by technology

[0016] None of the cited prior art documents disclose the use of anabolic amino acid derivative stimulators and vitamin D, as active compounds used together, for the prevention and / or treatment of muscle mass, muscle strength, muscle function and physical function in adult mammals , or any combination thereof, and a specific nutritional composition suitable for stimulating muscle protein synthesis in an adult mammal

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  • Nutritional composition for the stimulation of muscle protein synthesis
  • Nutritional composition for the stimulation of muscle protein synthesis

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Embodiment Construction

[0022] The present invention relates to the use of an anabolic amino acid derivative stimulus acting in conjunction with (combined) vitamin D, as well as compositions comprising said mutually active component, for the preparation of medicaments or A nutritional composition for preventing and / or treating loss of any of muscle mass, muscle strength, muscle function and body function, or any combination thereof, in a mammal, especially an adult mammal.

[0023] In the context of this application, the term "at least" also includes the beginning of an open range. For example, an amount of "at least 95% by weight" means an amount equal to or greater than 95% by weight.

[0024]In the context of this application, the term "about" means a deviation of less than 5% of the given value, such as 4%, 3%, 2%, 1% or less than 1%. For example, an amount of "about 12 g" refers to any amount equal to 12 g ± 0.6 g, ie, any amount in the range of 11.4 to 12.6 g. The reason for using the term "a...

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Abstract

The invention relates to the use of an anabolic amino acid derivative stimulus acting in combination with vitamin D for the manufacture of a medicament or nutritional composition for the prevention and / or treatment of a loss of any one of muscle mass, muscle strength, muscle function, and physical function, or any combination thereof, in a mammal.

Description

technical field [0001] The present invention relates to stimulators of anabolic amino acid derivatives acting in combination with vitamin D for the prevention and / or treatment of muscle mass, muscle strength, muscle function and physical function in mammals, especially adult mammals , or any combination thereof, and specific nutritional compositions suitable for stimulating muscle protein synthesis in mammals, especially adult mammals. Background of the invention [0002] Sarcopenia defines the loss of muscle mass, strength, and function that occurs during aging [1]. Muscle mass loss begins at a rate of 3-8% / year from the age of 30 and accelerates from the age of 60. This loss reaches up to 35-40% in the elderly over 70, and thus sarcopenia is particularly prominent in the elderly. [0003] Muscle mass maintenance can only be achieved through adequate stimulation of protein synthesis and / or inhibition of protein breakdown. Multiple factors contribute to muscle protein syn...

Claims

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Application Information

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IPC IPC(8): A23L1/29A23L1/303A23L1/305A61K31/198A61K31/59A61P21/06A23L33/00A23L33/155
CPCA23V2250/0614A23V2250/0628A61K31/198A23V2200/316A61K31/59A23V2250/306A23V2002/00A23L1/303A23L1/3051A23L1/296A23V2250/71A61K31/593A61K31/592A23L33/155A23L33/175A23L33/40A61P21/06A61K2300/00A23V2200/302A23V2250/54252
Inventor 马里昂-伊娃·阿德莱恩·乔丹伊薇特·查尔洛特·卢伊金乔治·韦尔兰索维亚尼·特尔博格
Owner NUTRICIA
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