1605 results about "Internal layer" patented technology

A device and method for selectively engaging or penetrating a layer of a luminal organ wall where the luminal organ wall has a plurality of layers including an outermost layer and an innermost layer adjacent to the lumen of the organ. The device and method select one of the plurality of layers of the organ wall other than the innermost layer and deploy from within the lumen of the organ a tissue device through the innermost layer to a specific depth to engage or penetrate the selected one of the plurality of layers. The device and method may be employed to create luminal pouches or restrictive outlets. In a stomach organ, the device and methods may be employed to treat obesity by forming a gastric pouch with or without a restrictive outlet.

The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the second composition comprises an effective amount of an adverse-effect agent. The adverse-effect agent is covered with a coating that is substantially insoluble in the gastrointestinal tract. In one embodiment, the adverse-effect agent is coated with an outer base-soluble layer and an inner acid-soluble layer. The therapeutic agent can be uncoated or can be coated with a coating having an outer acid-soluble layer and an inner base-soluble layer. The dosage form discourages administration of the therapeutic agent by other than oral administration.

The present invention relates generally to medical devices, preferably a stent, having a drug eluting surface coated or covered with a coating of particles comprising at least an outer layer, an inner layer, and a core comprising a therapeutic agent. Specifically, the invention relates to medical devices having a hydrophilic coating comprising particles with a hydrophilic outer layer, a hydrophobic inner layer, and a core comprising a hydrophobic therapeutic agent, as well as medical devices having a hydrophobic coating comprising particles with a hydrophobic outer layer, a hydrophilic inner layer, and a core comprising a hydrophilic therapeutic agent. The coating, outer layer, and inner layer are preferably biodegradable and capable of providing sustained release of the therapeutic agent over a time period. The invention also relates to methods of making and methods of using the coated or covered medical device.

A transluminal sheath is disclosed that permits instrumentation to be passed therethrough. The transluminal sheath comprises a composite structure with an inner layer, an outer layer, and a reinforcing layer. The materials comprising the inner and outer layer are plastically deformable and maintain their shape, once bent into a specific configuration. The reinforcing layer further has radiopacity enhancing coatings to improve visibility under fluoroscopy and a system of flutes running longitudinally, to enhance fluid transport and reduce friction.

Bag-in-container having an inner layer forming a bag filled with a fluid, the bag being separatable from an outer layer forming the container. The bag-in-container has a mouth fluidly connecting the volume defined by the bag to the atmosphere and separated therefrom by a seal. The container further having at least one space vent fluidly connecting the space between inner and outer layers and to the atmosphere. A vent provides a closure to control the gas flow between the space and the atmosphere. The space contains an amount of gas (Vs,i) at a pressure (Pi) insufficient to compress the bag to drive out more than 80% of the fluid contained therein. The present invention also concerns a kit of parts including a bag-in-container and a dispensing appliance.

An optical substrate guided relay (300) includes an optical substrate (302) having at least one major face (411), an output coupler (303) coupled to a major face (411,412), and an input coupler (301) coupled to a major face (411,412). The input coupler (301) is configured to reflect, via internal layers (414), portions of received light to the optical substrate 302. The input coupler (301) includes either one or more internal layers (414) or a contoured face (1040) with surfaces configured as reflectors that expand the received light and direct it into the optical substrate (302). The output coupler (303) expands a pupil of light in one direction and directs the expanded light away from the optical substrate guided relay.

Embolic protection and plaque removal apparatus and methods are provided wherein an aspiration device aspirates, filters and reperfuses blood using a closed fluid circuit having a bi-directional working lumen. The plaque removal device includes a plurality of self-expanding cutting elements that form cage that self-centers within the blood vessel to reduce the risk of trauma to the vessel lining.

Disclosed are implantable tissue augmentation devices, methods, and associated tools. The devices include an inflatable body, having an inner layer and an outer layer. A valve is provided for permitting the introduction of and retaining inflation media. At least one pull tab is provided on an end of the implant, to assist in positioning the implant. Kits and systems are also disclosed.

A disposable sleeve for compression therapy, with at least one inflatable air cell defined between a first airtight wall adjacent a patient's body to be treated and a second airtight wall. Each of the first and second walls comprises an external porous layer and an internal layer comprising air-tight polyethylene (PE). The walls are bonded by molten portions of the PE internal layer penetrating and set in their corresponding external porous layers and welded to each other, the bonding enduring at least 250 inflation-deflation cycles associated with the therapy.

The invention relates to balloon catheters (1) and methods of treatment for exerting internal pressure on surrounding tissue of a mammalian duct or cavity in a section thereof having a substantially circular cylindrical configuration. The elongate rigid distal section and the intermediate section of the catheter contain a central tube (3), whose distal part is provided with at least one outlet (23) for medium within the balloon, and whose intermediate part is surrounded by an axially displaceable tube (4), onto whose distal end the proximal end of the balloon is attached. The balloon has an envelope which is constituted by at least one substantially gas- and liquid-impermeable and elastic internal layer and an external layer of limited radial expansion, said expansion being substantially independent of the axial length of said balloon. The balloon may he encompassed by a radially expandible stent (40), or can be equipped with means for supplementing treatment using pressure with heat treatment.

A breathable and moisture permeable bra that is stylish, provides adequate support and is comfortable to wear is provided. Materials, such as wicking materials, for use in the bra, as well as other active wear, are also provided. The brassiere may include breast-supporting pads having a pad component including a perforated, molded foam cup encased by an inner and a first outer cloth layers and a second outer cloth attached to the outside of the pad component. The cloths may include materials that are breathable and may have wicking properties. In addition to the pad, the brassiere may include a wicking layer adapted to lie adjacent a wearer's skin to pull moisture away from the skin. The brassiere may also include an outer layer adapted to lie most distal the user's skin, that may provide an aesthetically pleasing exterior of the brassiere.

An optical substrate guided relay (300) includes an optical substrate (302) having at least one major face (411), an output coupler (303) coupled to a major face (411,412), and an input coupler (301) coupled to a major face (411,412). The input coupler (301) is configured to reflect, via internal layers (414), portions of received light to the optical substrate 302. The input coupler (301) includes either one or more internal layers (414) or a contoured face (1040) with surfaces configured as reflectors that expand the received light and direct it into the optical substrate (302). The output coupler (303) expands a pupil of light in one direction and directs the expanded light away from the optical substrate guided relay.

An integral de-nitrating catalyst SCR with dual oxides as carrier for removing NOx from fume is characterized by that the cellular cordierite ceramic is used as skeleton, its composite carrier is composed of Al2O3 as internal layer and TiO2 as external layer, and its active component consists of V2O5 and WO3. Its advantages are high activity, wide active temp window, and high effect and mechanical stability.

A dual-layer dilatation balloon includes an inner layer that includes a polymer selected from the group consisting of a polyester, polyether, polyamide and copolymers thereof, and an outer layer that includes a polyamide. The dual-layer balloon optionally further includes a stent disposed on the balloon. The stent is optionally a drug-eluting stent. A process for forming a dual-layer dilatation balloon includes forming a dual-layer extrudate having an outer layer that includes a polyamide and an inner layer that includes a polymer selected from the group consisting of a polyester, polyether, polyamide and copolymers thereof. The process also includes forming the dual-layer balloon from the dual-layer extrudate in a balloon forming machine, wherein the balloon has a hoop strength of about 10,000 to about 60,000 p.s.i.

A stent-graft assembly is provided for a variety of medical treatments. The stent-graft assembly includes a stent disposed between an inner layer of graft material and an outer layer of graft material. The graft layers are effectively secured to the stent by attaching the graft layers together through openings in the structure of the stent. Relative movement between the graft layers and the stent is made possible by providing unattached margins between the attached areas of the graft layers and the edges of the stent openings.

The inner plies of a multi-ply antimicrobial tissue product are selectively weakened by chemical or mechanical means to improve the overall softness of the tissue product. The addition of a deliquescent salt to the inner ply or plies containing the antimicrobial agent is particularly advantageous.

Disclosed are mask optics configured to be implanted in a cornea of a patient. In one embodiment, the body of the optic has a light transmitting portion, a light blocking portion disposed about the light transmitting portion, and an outer periphery surrounding the light blocking portion. The optic is adapted to reside between two intracorneal layers of a cornea. The mask optic may be formed from a material comprising a highly fluorinated polymeric material and an opacification agent. Preferred highly fluorinated polymeric materials include polyvinylidene fluoride (PVDF) and preferred opacification agents include carbon. The highly fluorinated polymeric material is preferably resistant to degradation upon exposure to ultraviolet light.

The invention is a polarized sunglass lens that utilizes a multiband contrast enhancer comprised of three rare-earth oxides to provide relatively high peak transmittance in portions of the red and green spectrum, relatively lower transmittance for the blue spectrum, and very low transmittance for the UV spectrum. The lens provides enhanced perception of colors, heightened contrast, and improved visual acuity. The inclusion of vanadium pentoxide in the lens provides attenuation of the UV spectrum, thus protecting the user's eyes and the internal layers and colorants from UV-induced damage. The front lens element can be either the multiband contrast enhancer or a photochromic lens element.

A multilayer balloon catheter is formed to have an inner layer and an outer layer, where the outer layer is adapted to resist shredding and premature rupture. The outer layer is formed of a material having a glass transition temperature that is lower than the transition or melting temperature of the inner layer. By forming the balloon on a mold at a temperature between the glass transition temperature of the outer layer and the glass transition or melting temperature of the inner layer, the outer layer will undergo a thermal relaxation that will alleviate some of the axial orientation of the polymer chains that develop during the formation of the multilayer balloon. This relaxation leads to a resistance to shredding when the balloon is expanded during operation.

A performance enhancing and force absorbing mouthguard adapted to fit the upper teeth of the mouth of an athlete wherein the mouthguard is of a composite material. The first internal layer is a nonsoftenable flexible framework which will permit the mouthguard to hold its shape during fitting as well as to absorb and dissipate significant impact conveyed to the upper teeth. The framework includes hard, durable bite plate wedges which lower the condyle from the temporomandibular joint in a fulcrum action to place the lower jaw in an optimum condition preventing impingement upon the nerves and arteries as well as spacing the upper and lower teeth apart. Elastomeric traction pads are on the bottom of the mouthguard and are grippingly engaged by the posterior teeth of the lower jaw. The elastomeric pads extend forwardly to form an anterior impact brace on the front of the mouthguard. While the framework and traction pads are mechanically interlocked, a softenable material is placed over the mouthguard excepting the contact portions of the traction pads and anterior impact brace to encapsulate the mouthguard and to permit custom fitting.

A phased-array antenna system and other types of radio frequency (RF) devices and systems using microelectromechanical switches (“MEMS”) and low-temperature co-fired ceramic (“LTCC”) technology and a method of fabricating such phased-array antenna system and other types of radio frequency (RF) devices are disclosed. Each antenna or other type of device includes at least two multilayer ceramic modules and a MEMS device fabricated on one of the modules. Once fabrication of the MEMS device is completed, the two ceramic modules are bonded together, hermetically sealing the MEMS device, as well as allowing electrical connections between all device layers. The bottom ceramic module has also cavities at the backside for mounting integrated circuits. The internal layers are formed using conducting, resistive and high-k dielectric pastes available in standard LTCC fabrication and low-loss dielectric LTCC tape materials.

Vacuum dressing sealed by an adhesive film (5) to which is coupled a suction tube (4) connected to a vacuum pump, said dressing comprising an external layer (2) of foam with open pores of large size, and a semi-permeable internal layer, characterized in that it constitutes a large integrated dressing incorporating a drainage device comprising tubes (9) with a plurality of holes (9a) at the ends thereof, one end being inserted in the external layer (2) and the other end in the operative plane (8).

A Z-directed switch component is mountable within the thickness of the PCB having a conductive trace on at least one of a top surface and bottom surface thereof, at least one internal layer having an internal conductive trace between the top and bottom surfaces and a mounting hole passing through the conductive traces on at least two of the top surface, the bottom surface and the at least one internal layer of the PCB. The Z-directed switch component comprises an insulative body having a top surface, a bottom surface and side surface, a length L, and a cross-sectional shape that is insertable into the mounting hole in the PCB. The side surface has a channel disposed therein extending toward the top and bottom surfaces. A compressive conductive member is disposed in and along the channel and having a portion thereof extending out beyond the side surface of the body. A turning structure on one of the top and bottom surfaces of the body for rotating the body when inserted into the mounting hole, wherein, with the Z-directed switch inserted into the mounting hole, the compressive conductive member electrically interconnects the conductive traces on at least two of the top surface, the bottom surface and the internal layer when rotated into alignment therewith.

A flame-retarding antistatic composite PVC pipe with high strength and toughness is composed of internal layer, reinforcing fibre or fabric layer and external antistatic layer. It can be made up by coextruding out method or layer-by-layer coating method.

An implantable medical lead and lead body, method of manufacturing the same, and a system and method for stimulating a portion of a body are disclosed. A lead body assembly is formed by preparing a first layer unitary body comprising a first plurality of conductors wound in a first direction. An inner layer of extrusion material is placed on the first layer unitary body. A second plurality of conductors coated with extrusion material is placed on the inner layer. The second plurality of conductors is wound in a second opposite direction. An outer layer of extrusion material is placed over the second plurality of conductors. Heat shrink tubing is placed over the assembly. The extrusion material is heated and melted and compressed around the conductors. When the heat shrink tubing is removed, the solidified extrusion material forms a protective wall that encapsulates the conductors in the lead body.

The present invention provides a method for manufacturing an identification document that can contain both common information and unique information describing the specific document holder. The information is in the form of indicia applied by digital imaging means. The document itself is in the form of a laminated article having the information affixed to one or more internal layers. Attempt to gain access to these internally imaged layers causes the image to be sufficiently disrupted as to prevent modifying such images.

A multilayer dielectric substrate includes a first signal via, a second signal via, an internal-layer signal line, an internal-layer ground conductor, and ground vias. The first signal via is connected to a bias-and-control-signal terminal of a high-frequency semiconductor, and is arranged within a region corresponding to the electromagnetic shielding members. The second signal via is arranged outside the region, and is connected to an external terminal for a bias and control signal. The internal-layer signal line connects between the first and the second signal vias. The internal-layer ground conductor is arranged around the first and the second signal vias and the internal-layer signal line. The ground vias are arranged around the first and the second signal vias and the internal-layer signal line, on the internal-layer ground conductor. A resistance film is provided on at least one of an upper surface and a lower surface of the internal-layer signal line.