A device and a method are provided for spatially locating and tracking an object, such as medical instruments, a patient and / or part of a patient's body using a camera array having at least two cameras, and for mutually assigning the spatial position of the object and an acquired, stored data set. Trackable markings are recorded via the camera array, the markings are extracted from the recordings, and a location of the markings is monitored, wherein the spatial position of the object is based on the location of the markings. Further, video recordings of a surface of the object are produced via the camera array and, with computer assistance, surface portions of the object are identified and correlated with corresponding surface portions in the stored data set, wherein the spatial position of the object is assigned to that of the data set.