34 results about "Chronic gastric ulcer" patented technology

The invention discloses a Chinese and western compound medicine for treating stomach diseases, which comprises seventeen traditional Chinese medicinal materials including pilose asiabell root, white atractylodes rhizome, Poria cocos, chicken's gizzard-skin, astragalus root, licorice root, haw, medicated leaven and malt, and a small number of Western medicinal materials including chloramphenicol, terramicin and furazolidone.

The invention provides an MG53 (mitsugumin53) mutant and a preparation method thereof. The mutant is a serine-site mutant of MG53 protein in a Coiled-coil structural domain, and the mutant results in inactivation of MG53 phosphorylation. Meanwhile, the MG53 protein mutant can be used for preventing or treating diseases related to cellular membrane damage, such as diseases related to myocardial cell injury, diseases related to ulcer, trauma with a wound, particularly a difficult-to-heal wound, intestinal leakage, kidney injury and the like. The diseases related to myocardial cell injury can include one or more diseases related to following symptoms: myocardial ischemia, heart ischemia, heart ischemia/reperfusion injury, myocardial infarction, cardiac failure, arrhythmia and cardiac rupture. The diseases related to ulcer include one or more of following diseases: chronic ulcer, peptic ulcer, diabetic foot ulcer, diabetic foot gangrene and chronic gastric ulcer. Besides, the invention further provides a dry powder preparation, a spray preparation, a gel preparation and an emulsion containing MG53 or MG53 mutant as well as preparation methods of the preparations.

The invention discloses an application of a herba schizonepetae-radix saposhnikoviae preparation in preparation of gastric ulcer treatment medicines and a preparation method of the herba schizonepetae-radix saposhnikoviae preparation, and belongs to the field of medicines. The herba schizonepetae-radix saposhnikoviae preparation is prepared from 11 raw medicinal materials including herba schizonepetae, radix saposhnikoviae, notopterygium root, doubleteeth pubescent angelica root, Chinese thorowax root, common hogfenneI root, szechuan lovage rhizome, fructus aurantii, poria cocos, platycodon grandiflorum and liquoric root and has the effects of inducing sweat, dispelling exogenous evils, dispelling wind and eliminating dampness. The herba schizonepetae-radix saposhnikoviae preparation can effectively treat stress gastric ulcer and acetic acid induced chronic gastric ulcer, inhibit gastric acid secretion and reduce free acid and total acidity in gastric juice, has the effect of reducingpepsase activity, treats both symptoms and root causes, and has an exact treatment effect on gastric ulcer.

The invention provides six cyclic dipeptides used for wound healing. The cyclic dipeptide is one of pro-phe, pro-pro, pro-val, pro-his, pro-tyr and pro-gly. The cyclic dipeptide has remarkable therapeutic effect on wound. Inhibition rate of acute and chronic gastric ulcer is high, wound healing speed of burns and scalds is fast, and scars are shallow.

The invention relates to a traditional Chinese medicine preparation for treating chronic gastric ulcer. The traditional Chinese medicine preparation for treating chronic gastric ulcer is prepared from the following raw materials including dendrobium officinale, combined spicebush roots, peach seeds, fingered citron, semen coicis, white hyacinth beans, Chinese thorowax roots, magnolia bark, pseudo-ginseng, myrrh, cyperus rotundus, liquorice, dandelions, roots of bidentate achyranthes, poria cocos, chicken's gizzardskin, fructus aurantii, ophiopogon japonicus, orange peel, bighead atractylodes rhizomes and boswellia carterii. The prepared traditional Chinese medicine preparation can solve the current problems and eliminate the root causes of the chronic gastric ulcer, has no side effects on a human body, is low in cost, can take effects fast and has wide application prospects.

The invention discloses a Chinese medicinal composition for treating chronic gastric ulcer, which relates to the technical field of traditional Chinese medicines. The Chinese medicinal composition is prepared from the following Chinese medicinal materials in parts by weight: 8-12 parts of common bletilla pseudobulb, 15-20 parts of dahurian angelica root, 3-6 parts of nardostachyos root and rhizome, 10-15 parts of hairyvein agrimonia herb and bud, 8-12 parts of areca nut, 8-12 parts of Chinese angelica, 8-12 parts of rhizoma corydalis, 8-12 parts of paniculate swallowwort root, 4-8 parts of amomum fruit, 20-30 parts of Chinese yam, 4-8 parts of coptis root and 8-12 parts of malaytea scurfpea fruit. The Chinese medicinal composition related to the invention has a remarkable curative effect on chronic gastric ulcer, can be used for tonifying spleen, regulating qi, dissipating swelling and relieving pain, and has high safety.

The invention relates to an application of Weichangan to preparation of drugs for preventing and treating alcohol-induced acute and chronic gastric ulcers. Animal experiments show that a Weichangan extract has obvious inhibiting effects on gastric ulcer in mice caused by 90% of short-term alcohol and 50% of long-term alcohol, so that Weichangan can serve as a drug for preventing and protecting alcoholic gastric ulcer. Weichangan has the obvious advantages that Weichangan has small treatment side effects on diseases, is small in dosage, has good effects and has not only good prevention effects but also better treatment and protection effects on alcoholic gastric ulcer.

The invention discloses a traditional Chinese medicine formula for treating chronic gastric ulcer. The traditional Chinese medicine formula is characterized by consisting of the following components in parts by weight: 14-18g of codonopsis pilosula, 13-17g of poria, 10-14g of roasted Chinese atractylode rhizome, 10-14g of Sichuan magnolia officinalis, 13-17g of tangerine peel, 10-14g of trogopterus dung, 10-14g of Chinese angelia root, 10-14g of coix seed, 10-14g of costustoot, 10-14g of bitter orange, 10-14g of radix rehmanniae, 10-14g of roasted ark shell, 10-14g of oriental stephania root, 8-10g of orange leaf, 12-16g of propolis, 10-14g of black jujubes, 10-14g of common burreed rhizome and 10-14g of ferrocholinate powder. The traditional Chinese medicine formula disclosed by the invention fully considers the advantages and disadvantages of each traditional Chinese medicine by years of practical experiences, and is reasonable in matching; and by adopting the traditional Chinese medicine formula, excessive gastric acid secretion can be effectively inhibited, the gastric mucosa can be protected, the resistance of the gastric mucosa can be enhanced, and the effect of fundamentally treating gastric ulcer can be achieved.

The invention discloses a traditional Chinese medicinal composition for treating chronic gastric ulcers, relates to a traditional Chinese medicinal formula, and aims to solve the problem that western medicine used for treating gastric ulcers has quick action but large side effect. The traditional Chinese medicinal composition comprises, by weight, 2-4 parts of longans, 1-3 parts of rhizoma atractylodis macrocephalae, 2-4 parts of bletilla striata, 2-5 parts of mangnolia officinalis, 1-4 parts of alpinia officinarum hance, 2-3 parts of pinellia ternata, 0.5-1.5 parts of peppers and 1-2 parts of codonopsis pilosula. The traditional Chinese medicinal composition for treating the chronic gastric ulcers has the advantages of good curative effect and small side effect.

The invention relates to the field of medicines, and in particular relates to stomach rehabilitation capsules for treating stomach diseases. The stomach rehabilitation capsules are characterized by consisting of the following raw materials in parts by weight: 10-20 parts of liquorice root, 10-20 parts of dahurian angelica root, 10-15 parts of codonopsis pilosula, 8-10 parts of panax notoginseng, 5-7 parts of milkvetch root, 5-7 parts of Saussurea costus, 3-5 parts of root of wilford swallowwort, 3-5 parts of barbed skullcap herb, 1-3 parts of aluminum hydroxide, 1-3 parts of calcium carbonate, 1-3 parts of starch, 0.1-0.3 part of chloromycetin and 0.1-0.3 part of terramycin. The stomach medicine disclosed by the invention has the effects of promoting qi circulation and relieving pain, astringing and promoting granulation, and promoting ulcer healing, and is mainly used for treating various acute or chronic gastric ulcers, reflux gastritis and atrophic gastritis and preventing the occurrence of stomach cancer. The stomach rehabilitation capsules disclosed by the invention can be clinically used for treating diseases such as gastrectasia, stomach stuffiness, stomachache, belching and gastric acid increase, nausea and vomiting, reduced appetite, fatigue and weakness, and constipation and unsmooth defecation, have the functions of dispelling cold and removing fever, activating blood and regulating qi, benefiting the stomach, tonifying the spleen and regulating the spleen and stomach, are short in treatment course, reliable in curative effect and very low in relapse rate, and can be prepared into capsule preparations to be conveniently taken.

The invention discloses a traditional Chinese medicine decoction for treating chronic skin ulcer. The traditional Chinese medicine decoction is prepared from the following traditional Chinese medicinal materials in parts by weight: 15 parts of angelica, 15 parts of ligusticum wallichii, 15 parts of peach kernel, 9 parts of bidentate achyranthes root, 15 parts of salix araeostachya, 30 parts of raw radix astragalis, 15 parts of eel blood, 9 parts of leaves of purpleflower holly, 5 parts of sapium baccatum, 5 parts of incarvillea younghustandii sprague, 12 parts of aizoon stonecrop herb, 6 parts of mutton tallow, 15 parts of herba pyrolae, 6 parts of raw liquorice, 6 parts of radix trichosanthis, 5 parts of sapium baccatum, 6 parts of wild sword beans and 6 parts of aizoon stonecrop herb. Clinical experiments prove that the traditional Chinese medicine decoction, by selecting proper medicinal materials and proportions thereof, can achieve a significant effect of treating chronic skin ulcer, and the traditional Chinese medicine decoction is safe and free from toxic or side effect.

The invention relates to a stomach disease treating drug, which is prepared from the following components by weight, 20-30 parts of malt, 10-15 parts of dried ginger,12-18 parts of coptis chinensis, 10-20 parts of egg shell, 5-20 parts of hawthorn, 15-25 parts of fructus aurantii, 5-10 parts of clove, 15-23 parts of salvia miltiorrhiza, 12-20 parts of coptis chinensis, 15-25 parts of the leaf of eupatorium japonicum thunb, 10-15 parts of smilax glabra roxb, and 5-12 parts of cape jasmine. According to the present invention, the stomach disease treating drug has advantages of simple and easy-performing preparation method, short treatment course, no toxic-side effect, significant treatment effect, rapid treatment effect, no requirement of other expensive assisted treatment, low cost, painless and non-invasive use and no recurrence after cure, and can be used for treating various types of acute and chronic gastric ulcers and gastritis.

The invention discloses a preparation for treating chronic gastric ulcer. The preparation is prepared from, by weight, 11-16 parts of Herba Ajugae, 13-17 parts of Radix Curcumae, 13-16 parts of Folium seu Radix Uvariae, 9-15 parts of Herba Psiloti, 13-18 parts of Bulbus Allii Macrostemonis, 13-17 parts of Flos Lilii, 11-15 parts of Radix Calystegiae Sepium, 9-14 parts of Herba Belladonnae, 13-16 parts of Radix Pruni Dimonii, 7-12 parts of Caulis Cucurbitae, 9-14 parts of Radix Helicteris Isorae, 11-15 parts of beta vulgaris, 9-15 parts of Fructus Juniperi Rigidae, 11-16 parts of Radix Fici Beecheyanae and 8-12 parts of Semen Oroxyli. The preparation is obtained by refining of the common Chinese herbal medicines which have synergistic effects to jointly function in heat clearing, blood cooling, spleen nourishing, stomach notifying, liver Qi discharging and regulating, stomach tonifying and body fluid secretion promoting, and the preparation is effective in inhibition of hyperacidity to protect gastric mucosa and capable of enhancing resistance of the gastric mucosa to realize radical cure of gastric ulcer.

The invention relates to traditional Chinese medicine preparation for treating chronic gastric ulcer or duodenal ulcer. The traditional Chinese medicine preparation is characterized by being prepared by, by weight, 250g of red halloysite, 30g of lignum dalbergiae odoriferae, 60g of bletilla striata, 60g of rhizoma cyperi, 60g of prepared liquorice, 30g of radix astragali, 30g of bighead atractylodes rhizome, 10g of rhizoma coptidis and 30g of medicated leaven. The traditional Chinese medicine preparation has the advantages that the traditional Chinese medicine preparation has good pain relieving, hyperacidity relieving and astringency and hemostasis effects and is good in curative effect on the chronic gastric ulcer or duodenal ulcer, chronic inflammation can be eliminated when patients persistently take the traditional Chinese medicine preparation for a certain period of time, and secondary ulcer can be prevented; the ulcer of most patients can be healed and thoroughly cured when the patients persistently take the traditional Chinese medicine preparation for 2-6 months.