The invention discloses a desulfurization waste water zero discharge processing system and a processing method. The desulfurization waste water zero discharge processing system comprises a regulation sedimentation basin, triple connecting tanks, a defecator and a nanofilter which are connected in sequence, wherein the concentrated water outlet end of the nanofilter is connected with a mistorizer which sprays the concentrated water into a chimney flue; the triple connecting tanks include a neutralization tank, a reaction tank and a flocculation tank which are connected in sequence, wherein the neutralization tank is communicated with the water outlet of the regulation sedimentation basin, and is used for adjusting the pH value of desulfurization waste water, so that bicarbonate ions in the desulfurization waste water are removed; the reaction tank provides a reaction chamber for removing calcium ions in the desulfurization waste water; the flocculation tank is connected with the defecator. The desulfurization waste water zero discharge processing system and the processing method have the advantages of saving the cost of the agent for removing magnesium ions in the desulfurization waste water, reducing the quantity of sludge, lowering the operating cost, using no lime milk and improving the site working conditions. The sodium chloride salt in the waste water is purified and then crystallized, thus the recycle of the sodium chloride salt in the desulfurization waste water is achieved, the solid waste disposal cost is reduced, and certain economic benefits are produced.