The invention discloses a matrix type structure of a dustproof, waterproof and sound-transmitting film of a micro electro mechanical sensor. The structure comprises a supporting layer, a dustproof andwaterproof acoustic transmission film, an adhesive, a PCB and acoustic sensors; one face of the supporting layer is adhesive and adheres to one face of the dustproof and waterproof acoustic transmission film, the other face of the dustproof and waterproof acoustic transmission film adheres to the upper surface of the PCB through the adhesive, and the acoustic sensors are installed on the lower surface of the PCB; the acoustic sensors, the support layer sound hole, the dustproof and waterproof acoustic transmission film vibration area, the adhesive sound hole and the PCB sound hole form an acoustic channel; the multiple acoustic sensors are distributed on the lower surface of the PCB in a matrix mode, so the matrix type dustproof, waterproof and sound-transmitting film structure is correspondingly formed; the waterproof film adheres to the PCB through an adhesive, and batch products can be produced at a time. The acoustic sensors are covered with the expanded polytetrafluoroethylene film formed by the highly-fibrillated ePTFE microstructure, and the structure has the insertion acoustic loss lower than 5 dB under 1 kHz and the water pressure resistance of at least one meter or above.