30results about How to "Solving Detection Errors" patented technology

The cartridge stores the ink liquid supplied to the ink-jet head of the ink-jet printer in the ink pouch, and includes: a liquid supply port for allowing the ink liquid stored in the ink pouch to be supplied to the ink supply tube of the printer by connecting a liquid supply needle (not shown in the drawing) provided in the cartridge mounting portion when the ink cartridge is mounted on the cartridge mounting portion of the ink-jet printer; a remaining amount detection sensor which outputs a predetermined electric signal for notifying the main controller of the ink-jet printer of a fact that the remaining amount of the ink liquid reaches the near end when the remaining amount of the ink liquid stored in the ink pouch is consumed to the threshold value which is the near end; and an information memory from / to which information is readable and writable by the main controller of the ink-jet printer. The information memory stores correction information for correction the detection error of the remaining amount detection sensor when the near end is detected.

The invention discloses a miniature flow cytometer fluid path system. The system comprises a flowing chamber, a sample pipeline, a sheath fluid pipeline, a waste fluid pipeline and a gas pipeline. A sample to be tested is conveyed via a small-flow peristaltic pump and then flows into the flowing chamber after passing through a pulse buffer; sheath fluid is conveyed via a large-flow peristaltic pump or a diaphragm pump and then unilaterally or symmetrically flows into the flowing chamber after passing through a bag type filter element and the pulse buffer; a miniature air pump is connected to the flowing chamber via an one-way valve so as to remove pipeline bubbles. A pressure sensor is mounted at the exit of the flowing chamber and is used for monitoring pressure change and abnormity. A liquid level sensor is arranged in each of a sheath fluid pool and a waste fluid pool and is used for setting a liquid level alarm. A filter screen is mounted at the atmospheric connection part of the sheath fluid pool and the miniature air pump to prevent impurities from entering. Through the omission of an air pressure pump in a traditional miniature flow cytometer, the miniature flow cytometer fluid path system is simple in structure and convenient to clean, has the function of removing bubbles and can meet the application requirement on miniaturization of the miniature flow cytometer.

The invention provides a method for improving detection near-space precision. The method comprises the following steps: under a calibration mode, recording a first calibration propelling quantity NE1when a light blocking sheet on a moving component of an injector blocks a photoelectric switch on an injection pump, and recording an empty propelling quantity NE2 when a piston of the injector movesto the end; calculating a calibration relative quantity difference delta NE between the first calibration propelling quantity NE1 and a near-space relative quantity NE0 according to the preset near-space relative quantity NE0 of the injector, the first calibration propelling quantity NE1 and the empty propelling quantity NE2; and under a normal injection mode, recording a first propelling quantityE1 when the light blocking sheet blocks the photoelectric switch, using the difference of a real-time second propelling quantity E2 recorded when the piston of the injector moves and the first propelling quantity E1 as a working relative quantity difference E3 to be compared with the calibration relative quantity difference delta NE, and judging that the injector is propelled to a near-space state when the working relative quantity difference E3 is greater than the calibration relative quantity difference delta NE.

The invention discloses a copy number variation detection method based on next generation sequencing. The method comprises the following steps: pre-processing copy number variation data, constructing a sliding window, calculating of statistics, implementing a replacement policy, constructing zero distribution, and carrying out performance evaluation of an algorithm. The performance evaluation of the algorithm comprises the steps of judging whether a relatively high correct positive rate can be acquired by the algorithm under the condition that a false positive rate is controllable, evaluating whether the algorithm can relatively accurately estimate a p value or not, detecting a boundary detection capability of copy number variation, and analyzing the calculation complexity of the algorithm. With the adoption of the copy number variation detection method, the problem of copy number variation detection errors, caused by the fact that sequencing platforms and sequencing levels are different, is solved, and a result is relatively accurate; data is normalized by utilizing characteristics of a multi-peak frequency histogram, so that a normal region and a copy number variation region are accurately divided; and a new model is established by a comprehensive effect of relevance between a variation reads number and a variation site, so that the inconsistency problem is solved, and the remarkable level of copy number variation is objectively estimated.