The invention discloses a bottom uniform booster-type vacuum preloading treatment method. The method includes the steps that A, a preloading pit is formed through excavation; B, air inflation pipes are pre-buried in the preloading pit, the air inflation pipes include the bottom air inflation pipes which are pre-buried at the bottom of the preloading pit and vertical air inflation pipes which are vertically upward and connected with air inflation devices outside the preloading pit, exhaust holes are densely distributed in the upward sides of the bottom air inflation pipes, the bottom air inflation pipes are connected with the vertical air inflation pipes in a guiding mode, and the vertical air inflation pipes are sleeved with springs; C, a soil body needing to be subjected to vacuum preloading treatment is conveyed to the inside of the preloading pit, drainage plates are buried and connected with a pump drainage pipeline and a pump drainage device which are located on the upper portion, and the soil body is covered with sealing cloth; D, the pump drainage device is started to make the drainage plates pump water in the soil body till the pump drainage water amount is obviously reduced; and E, the air inflation devices are started to inflate the bottom air inflation pipes through the vertical air inflation pipes, the bottom air inflation pipes inflate the soil body upwards, and the pump drainage device works at the same time. By means of the bottom uniform booster-type vacuum preloading treatment method, when the pump drainage effects of the drainage plates are reduced greatly, the bottom of the soil body can be inflated, the water is squeezed and gathered to the drainage plates, the drainage effect is further improved, and the water in deep layer soil can also be pumped and drained.