The invention provides an organic electroluminescent device and a preparation method thereof, and a flexible display device. The organic electroluminescent device includes a flexible substrate, an OLED display device arranged on the flexible substrate, an encapsulated layer covering the OLED display device, a bonding layer bonding on the face, away from the flexible substrate, of the encapsulatedlayer, a cover plate bonding on the face, away from the flexible substrate, of the bonding layer, and a fibrous layer arranged between the bonding layer and the cover plate; the face, facing to the cover plate, of the bonding layer has a first patterned structure; the face, facing to the bonding layer, of the cover plate has a second patterned structure fitting with the first patterned structure;and at least partial areas of the fibrous layer is fitted between the first patterned structure and the second patterned structure. Thus, the shedding of the cover plate and the encapsulated layer after the flexible display device is bended for many times can be solved, even the adverse phenomenon of cover plate fracture, and the service life of the flexible display device can be prolonged.