The invention provides a portable medical safe transfer trolley for intensive care. The portable medical safe transfer trolley comprises a base plate, a trolley body, a trunk plate, an upper limb plate, a lower limb plate, a trolley head baffle, a trolley tail baffle, a cleaning device, an oxygen delivery device and traveling wheels, wherein the trolley body is fixed to the upper surface of the base plate, the trunk plate is arranged on the upper surface of the trolley body and is of a hollow structure, the drawable upper limb plate is arranged at the left side of the trunk plate, the drawable lower limb plate is arranged at the right side of the trunk plate, the trolley head baffle is arranged on the upper limb plate, the trolley tail baffle is arranged on the lower limb plate, the cleaning device and the oxygen delivery device are arranged in the trolley body, and the multiple traveling wheels are evenly distributed on the lower surface of the base plate. The portable medical safe transfer trolley is simple in structure and convenient to use. The upper limb plate and the lower limb plate can be pulled out or not as needed so as to facilitate carrying on the premise that using is not affected. Relevant space for nursing is arranged in the trolley body, arrangement is reasonable, space is saved, nursing is not affected during transfer of patients, and pains of patients and working difficulty of medical staff are reduced.