The invention provides a method and device for dynamic cooperation resource distribution in a heterogeneous network. The method comprises the following steps executed by an interference coordination module: A, collecting a direct parameter set, an indirect parameter set and a current ABS density or mode, wherein parameters in the direct parameter set are used to dynamically calculate a new ABS density; B, according to the direct parameter set, the current ABS density and a predefined parameter, dynamically calculating the new ABS density, and selecting a corresponding new ABS mode according to the new ABS density; and C, sending the new ABS mode. The interference coordinate module locates in a macro base station or a central cooperation node. On the basis of the scheme of the invention, according to a load condition of a current macro cell, load conditions of small cells and the number of the small cells in the macro cell, the optimum ABS mode can be calculated, and the calculation process is very simple and fast. And, for different initial conditions of given user distribution, the cell business amount, the cell switching bias configuration and the like, the rapid-convergence optimum ABS density can be obtained, and then the optimization process is relatively smooth and stable.