The invention relates to a method for improving unattended safety level of a transformer station, belonging to the power supply field. The method comprises the step of dividing a transformer station into three main parts to form three centralized control stations, namely a ninth main transformer station, a tenth main transformer station and a thirteenth transformer station, wherein the three centralized control stations respectively carry out centralized control on nearby transformer stations, that is the ninth main transformer station controls a fourth transformer station, a sixth transformer station, a seventh transformer station and a sixteenth transformer station, the ninth main transformer station controls a second transformer station, a third transformer station, an eleventh transformer station, a fourteenth transformer station and a fifteenth transformer station, and the thirteenth transformer station controls a first transformer station, a fifth transformer station, an eighth transformer station, a twelfth transformer station and a seventeenth transformer station. The method for improving the unattended safety level of the transformer station, disclosed by the invention, has the advantages of greatly improving stability of a monitoring system, improving the work efficiency of an operator, reducing the work load of electric power schedule, reducing labor demand, increasing efficiency and relieving the shortage of labors, and effectively ensuring safe and stable running of an electric power system.