The invention discloses a structure of an electronic product enclosure panel and a manufacturing process thereof. In the invention, metal with characteristics of good radiation protection effect, high strength, high-temperature resistance and the like, and plastic cements with characteristics of light weight, convenience of structure machining and the like are fully combined to realize injection molding on the metal surface through an intermediate medium hot melt adhesive membrane, so that a purpose of fixing and combination of a metal panel and a plastic element is reached, and an electronic product enclosure panel using the metal panel as the enclosure external surface and using the plastic element as the structural element is manufactured, therefore, the electronic product enclosure panel has the advantages of good radiation protection effect, high strength, corrosion resistance, high-temperature resistance, attractiveness, light weight, convenience for machining and the like and can manufacture complex structural elements and the like.