The invention discloses a drunk driving prevention monitoring and control system, which belongs to the technical field of traffic safety monitoring systems, and comprises a plurality of alcohol sensors, a signal receiving module, a control module, a signal transmitting module, a signal collector and an information processing module, wherein the alcohol sensors are uniformly distributed at all corners in an automobile, the signal receiving module is connected with the alcohol sensors, the information processing module is connected with the signal receiving module, the control module is connected with the information processing module, the signal transmitting module is connected with the control module, and the signal collector is connected with the signal transmitting module. Whether a driver has a drunk driving behavior or not can be monitored, meanwhile, a monitoring system can be prevented from being damaged manually, and the drunk driving phenomenon can be effectively reduced; the system has very important significance in reducing traffic accidents caused by drunk driving and guaranteeing the life and property safety of people, and has very high application and popularization value.