The invention discloses an automatic mechanism hand drive mechanism used for material turnover, which comprises a Z-axial drive part, wherein the drive part comprises a supporting part, the supporting part is equipped with a guide rail and a first slide block coordinated with the guide rail, the first slide block is firmly connected to a Z-axial supporting arm, the first slide block is coordinated with a screw rod, the screw rod is connected by a first servo motor and driven by a synchronous belt to make the first slide block move up and down, a rotation part is disposed above the Z-axial supporting arm, and an X-axial drive part is connected above the rotation part; the axial drive part comprises a horizontal arm part which is equipped with a second slide block, wherein the second slide block moves horizontally on a horizontal arm guide rail; and the second slide block is equipped with a clamping hand device. The automatic mechanism hand drive mechanism used for the material turnover is characterized by a simple structure, easy manufacture, strong flexibility, high intelligence, stable actions and operations, high mechanical reliability and strong bearing capacity.