41 results about "Tropane alkaloid" patented technology

A method for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method comprises attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to the antigens in the array to form immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, to form an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

The present invention provides a method for the N-demethylation of an N-methylated heterocycle, particularly a morphine or tropane alkaloid or derivative thereof. The method comprises reacting the heterocycle with a metal catalyst and a solvent in the presence of an oxidizing agent.

The invention discloses a radix anisodii acutanguli 1,4-putrescine-nitrogen-methyltransferase gene1, protein which is encoded by the radix anisodii acutanguli 1,4-putrescine-nitrogen-methyltransferasegene1, and the use thereof, which fills a gap that the 1,4-putrescine-nitrogen-methyltransferase gene is separated and cloned from radix anisodii acutanguli which is a specific medicinal plant in Yunnan, China. The radix anisodii acutanguli 1,4-putrescine-nitrogen-methyltransferase gene1 which is provided by the invention has a nucleotide sequence or a homologous sequence which adds, replaces, inserts or losses one or a plurality of nucleotides or allele thereof and the nucleotide sequence which is derived from the radix anisodii acutanguli 1,4-putrescine-nitrogen-methyltransferase gene1, which are displayed in the SED ID No.1. The protein which is encoded by the gene has an amino acid sequence or the homologous sequence which adds, replaces, inserts or losses one or a plurality of aminoacids, which is displayed in the SEQ ID No.2. The 1,4-putrescine-nitrogen-methyltransferase gene which is provided by the invention has prominent effect of increasing the content of tropane alkaloid in plants such as the radix anisodii acutanguli and the like through the genetic engineering technology and can be widely applied in improving the quality of resource plants which produce tropane alkaloid.