31 results about "OCT - Optical coherence tomography" patented technology

The present invention relates to a rotating catheter tip for optical coherence tomography based on the use of an optical fiber that does not rotate, that is enclosed in a catheter, which has a tip rotates under the influence of a fluid drive system to redirect light from the fiber to a surrounding vessel and the light reflected or backscattered from the vessel back to the optical fiber.

An endoscopic swept-source Fourier Domain optical coherence tomographic system (FDOCT system) for imaging of tissue structure includes a Fourier Domain mode locked (FDML), high speed, narrow line-width, wavelength swept source, an OCT interferometer having a sample arm, a reference arm, a detection arm, and a source arm coupled to the swept source, an endoscopic probe coupled to the sample arm, and a data processing circuit coupled to the detection arm. The swept source includes a long optic fiber functioning as a cavity, a high optical gain lasing module, and a tunable narrow bandwidth bandpass filter for wavelength selection combined to form a unidirectional ring laser cavity, where the tunable narrow bandwidth bandpass filter is driven synchronously with the optical round-trip time of a propagating light wave in the cavity.

The invention aims to provide a full-eyeball optical coherent tomography adaptive system and a full-eyeball optical coherent tomography adaptive method. Compared with the prior art, the full-eyeball optical coherent tomography adaptive system and the full-eyeball optical coherent tomography adaptive method have the advantages that the problem that high-quality OCT (optical coherent tomography) images cannot be simultaneously acquired at ocular anterior segments and ocular posterior segments by means of optical coherent tomography in the prior art can be effectively solved, focusing can be simultaneously carried out on ocular anterior segments and ocular posterior segments by a multi-focus imaging arm, and reference arms with different optical path differences are switched and are combined with the imaging arm, so that the ocular anterior segments and the ocular posterior segments can be imaged simultaneously; aberration introduced at the ocular anterior segments can be computed in real time by the aid of images of the ocular anterior segments, and aberration compensation can be carried out by the aid of a phase modulation array in the imaging arm, so that the high-quality OCT images can be simultaneously acquired at the ocular anterior segments and the ocular posterior segments by the aid of the full-eyeball optical coherent tomography adaptive system and the full-eyeball optical coherent tomography adaptive method.

The invention relates to a method for generating an image using optical coherence tomography, with a control device controlling the operation of an image generation device and a rinsing device automatically according to a predetermined program.

An imaging method is disclosed. An imaging method according to some embodiments can include obtaining a plurality of measurements of an eye for at least one location by scanning optical radiation across the eye; determining a preferred measurement axis from the plurality of measurements; and processing the plurality of measurements to obtain information of the eye.

The invention discloses an optical coherence tomography (OCT) endoscope imaging device. The OCT endoscope imaging device comprises an endoscope with an OCT imaging system, wherein the OCT imaging system comprises a light source I, a mixer, a probe, a reference arm and a sample arm; an input end of the mixer is connected with an output end of the light source I by an optical fiber or a space optical path; an output end of the mixer is connected to the reference arm and the sample arm by the optical fiber or the space optical path; an input end of the probe is connected to the output end of the mixer by the optical fiber or the space optical path; an output end of the probe and another output end of the light source I are respectively connected with an input end of a calculation control unit; and an output end of the calculation control unit is connected to an input end of the sample arm. By the endoscope device, nondestructive testing on viable tissues in the human body can be performed; and the device has micro-grade high resolution and is imaged in real time, can help doctors to diagnose the pathology in time, and is also used for industrial endoscope fields.

The image sensing apparatus comprises a first scan unit for scanning light from an OCT light source and light from an SLO light source in a first direction of a test object, and a second scan unit for scanning the light from the OCT light source in a second direction different from the first direction of the test object. The image sensing apparatus acquires tomographic images of the test object along the first direction when the first scan unit scans the light from the OCT light source, and acquires cross-over images of the test object corresponding to the tomographic images when the first scan unit scans the light from the SLO light source.

Based on optical coherence tomography (OCT) imaging of a portion of an eye, a mask of an anatomical feature is derived. Using the mask as a reference, a scan path is determined that is at least partially fitted to and / or partially enclosing the mask. OCT scan data corresponding to the scan path is acquired and analyzed to detect optic neuropathies.

An optical coherence tomograph that provides wavelength tunable source radiation and an illumination and measurement beam path, a dividing element that divides source radiation into illumination radiation and reference radiation, and collects measurement radiation. The illumination and measurement beam path has scanner. A detection beam path receives measurement radiation and reference radiation and conducts them onto at least one flat panel detector in a superposed manner. A beam splitter separates the measurement radiation from the illumination radiation. The beam splitter conducts the separated measurement radiation to the detection beam path and sets the numerical aperture of the illumination of the illumination field in the eye. An optical element sets the numerical aperture with which the measurement radiation is collected in the eye and a multi-perforated aperture defines the size of an object field and a number of object spots, from which the measurement radiation reaches the flat panel detector.

This disclosure relates to the field of Optical Coherence Tomography (OCT). This disclosure particularly relates to methods and systems for providing larger field of view OCT images. This disclosure also particularly relates to methods and systems for OCT angiography. This disclosure further relates to systems for health characterization of an eye by OCT angiography. This OCT angiography system may determine a feature of a vasculature within an eye tissue and thereby identify a vascular anomaly and a spatial location of the vascular anomaly within the eye tissue.

Measuring light with a wide wavelength band is used to provide a tomographic image excellent in vertical resolution. An optical coherence tomography apparatus acquiring a tomographic image of an object to be inspected based on an interference light obtained by causing a return light from a measuring light emitted onto the object to be inspected to interfere with a reference light corresponding to the measuring light, includes: a first dispersion compensation unit having a first dispersion compensation characteristic in a wavelength band of the measuring light; a second dispersion compensation unit provided onto the first dispersion compensation unit and having a second dispersion compensation characteristic in the wavelength band of the measuring light.

An optical coherence tomography method according to the present invention comprises the steps of dividing an object to be measured into a plurality of measurement regions adjacent to one another in a direction of irradiation of a measurement light, and acquiring a measurement image for every measurement region based on a wavelength spectrum of a coherent light; correcting, for every measurement region, a contrast of the measurement image of the measurement region; and acquiring, for every measurement region, a tomographic image from the corrected measurement image.

The invention provides an optical coherence tomography apparatus. Measuring light with a wide wavelength band is used to provide a tomographic image excellent in vertical resolution. An optical coherence tomography apparatus acquiring a tomographic image of an object to be inspected based on an interference light obtained by causing a return light from a measuring light emitted onto the object to be inspected to interfere with a reference light corresponding to the measuring light, includes: a first dispersion compensation unit having a first dispersion compensation characteristic in a wavelength band of the measuring light; a second dispersion compensation unit provided onto the first dispersion compensation unit and having a second dispersion compensation characteristic in the wavelength band of the measuring light.

In accordance with some embodiments, a method of eye examination includes acquiring OCT data with a scan pattern centered on an eye cornea that includes n radial scans repeated r times, c circular scans repeated r times, and n* raster scans where the scan pattern is repeated m times, where each scan includes a A-scans, and where n is an integer that is 0 or greater, r is an integer that is 1 or greater, c is an integer that is 0 or greater, n* is an integer that is 0 or greater, m is an integer that is 1 or greater, and a is an integer greater than 1, the values of n, r, c, n*, and m being chosen to provide OCT data for a target measurement, and processing the OCT data to obtain the target measurement.

System and method for 3D retinal disruption / elevation detection, measurement and presentation using Optical Coherence Tomography (OCT) are provided. The present invention is capable of detecting and measuring the abnormal changes of retinal layers (retinal disruptions), caused by retinal diseases, such as hard drusen, soft drusen, Pigment Epithelium Detachment (PED), Choroidal Neovascularization (CNV), Geographic Atrophy (GA), intra retinal fluid space, and exudates etc. The presentations of the results are provided with quantitative measurements of disruptions in retina and can be used for diagnosis and treatment of retinal diseases.

The invention discloses a high strength probe used for optical coherence tomography imaging. The high strength probe comprises a single-mode optical fiber, a grin-lens, a refraction lens, high scattering rate heat shrink tubes, a torque cable, a sealing cap and a protection sleeve. The single-mode optical fiber, the grin-lens and the refraction lens are connected together from left to right in sequence, the left end of the single-mode optical fiber is located in the hollow torque cable, the high scattering rate heat shrink tubes cover the torque cable, the single-mode optical fiber, the grin-lens and the refraction lens from left to right in sequence to form a probe structure, the protection sealing cap is installed at the right end of the probe structure, the probe structure is installed in the protection sleeve, and the torque cable transmits torque generated by an OCT system to the probe structure, so that the probe structure performs rotary motion and displacement translational motion in the protection sleeve.

There is provided an apparatus (100; 200) for recording a depth profile of a biological tissue, in particular a frontal eye section (140) of a human eye, according to the principle of optical coherence tomography, comprising a light source (101) adapted to generate a bundle (102) of light rays comprising wavelengths in a predetermined wavelength range with a predetermined bandwidth (??) and comprising an operating wavelength (?0), an interferometer arrangement having a beam splitter device (120) adapted to spatially separate the bundle of light rays generated by the light source into a reference beam (104; 204) and a measurement beam (106) directed toward the tissue, a reference beam deflection device (130; 230) adapted to deflect the reference beam, a beam superpositioning device (150) adapted to spatially superimpose the deflected reference beam onto the measurement beam deflected by the tissue into a superpositioned beam (108; 208), and a detector arrangement (160, 170; 270) for detecting information in the superpositioned beam associated with the difference of the optical path length of the reference beam and the measurement beam. The predetermined wavelength range is a range from 300 nm to 500 nm, preferably from 350 nm to 450 nm and more preferably next to 403 nm.

Optical coherence tomographic imaging apparatus creating tomographic image of inspection object includes light splitting means for splitting light from light source into a single reference light and a single sample light, optical path length changing means for changing optical path length of the single reference light, reference light splitting means for splitting the single reference light whose optical path length is changed into a plurality of reference lights, sample light splitting means for splitting the single sample light into a plurality of sample lights, irradiation means for irradiating the inspection object by leading the plurality of sample lights thereto, interference signal forming means for combining returning lights of the plurality of the sample lights from the inspection object irradiated by the irradiation means with the plurality of reference lights passed through the reference-light path, and interference signal obtaining means for obtaining an interference signal from the interference signal forming means.

The invention discloses an optical coherence tomography system. The system comprises a Fourier domain optical coherence tomography sensor system, a signal processing system and an image display system, wherein the signal processing system can be communicated with the Fourier domain optical coherence tomography sensor system to receive a detecting signal and provide an imaging signal; the image display system is used for being communicated with the signal processing system to receive the imaging signal, and the image display system comprises a parallel processor which can be used to calculate three-dimensional structure information and Doppler information from the detecting signal in real time so as to allow the imaging signal to be able to provide the combined structure and flowing real-time three-dimensional structure of an observation target.

Measuring light with a wide wavelength band is used to provide a tomographic image excellent in vertical resolution. An optical coherence tomography apparatus acquiring a tomographic image of an object to be inspected based on an interference light obtained by causing a return light from a measuring light emitted onto the object to be inspected to interfere with a reference light corresponding to the measuring light, includes: a first dispersion compensation unit having a first dispersion compensation characteristic in a wavelength band of the measuring light; a second dispersion compensation unit provided onto the first dispersion compensation unit and having a second dispersion compensation characteristic in the wavelength band of the measuring light.

The invention relates to the technical field of medical imaging devices, and provides an optical coherence tomography imaging handheld probe which comprises an optical treatment module. The optical treatment module comprises a collimating lens, an MEMS galvanometer, a focusing lens set, a right-angle reflection prism and a reflector set which are sequentially arranged along a light path, incident light from the focusing lens set is divided into two beams of reflection light rays by the right-angle reflection prism through reflection of two right-angle surfaces, the reflection light rays are reflected by the reflector set, and two beams of relative emergence light rays are outputted. According to the probe, when a pre-imaged blood vessel is observed, the blood vessel is placed between two beams of relative emergence light rays, deflection of the MEMS galvanometer is controlled and adjusted, so that the blood vessel can be scanned in two directions, a section structure of the blood vessel is observed through two sides in a bidirectional scanning process, effective depth of blood vessel imaging is greatly increased, and imaging definition is ensured.

In a polarization-sensitive optical coherence tomography system, an interferometer includes single mode fibers and a plurality of polarization controllers. At least one of the plurality of polarization controllers is disposed on each of the fibers of the interferometer. The fibers include a fiber for sample light beam, a fiber for reference light beam, and a fiber for detection light beam. An image forming unit determines a pixel value from a data set consists of two orthogonal polarization components simultaneously obtained at substantially identical spatial positions of a test sample, wherein a measurement light beam has static single polarization state.

A method of processing optical coherence tomography (OCT) scans through a subject's skin is provided. The method comprises: receiving at least one OCT scan through the subject's skin, wherein each scan represents an OCT signal in a slice through the subject's skin; processing each OCT scan so as to determine a set of parameters comprising at least a measure of the atrophy of the vascular structurein the epidermis; in which the processing produces a measurement of skin condition dependent upon each of the set of parameters, and the method comprises outputting the measurement of skin condition.

An ophthalmic surgery microscope comprising a beam coupler positioned between a first eyepiece and magnification / focus optics along an optical path of the surgical microscope, the beam coupler being operable to The OCT imaging beam is directed along a first portion of an optical path of the surgical microscope between the beam coupler and a patient's eye (the OCT image is generated based on a reflected portion of the OCT imaging beam). The surgical microscope further comprises: a real-time data projection unit operable to project OCT images produced by the OCT system; and a beam splitter along the surgical The optical path of the microscope is positioned between the second eyepiece and the magnification / focus optics. The beam splitter is operable to direct the projected OCT image along a second portion of the optical path of the surgical microscope between the beam splitter and the second eyepiece such that the projected OCT image can be viewed through the second eyepiece.

The invention discloses an optical coherence tomography scanner used for diagnosis in the ophthalmology department. A fixed support is arranged on the right side of an optical coherence tomography scanner box and provided with a forehead bracket, an adjusting handle is fixedly connected to the right side wall of the optical coherence tomography scanner box through a fixing rod, a left fixed frameis arranged at the top of the adjusting handle, an upper supporting frame is arranged at the top of the left fixed frame, an upper spherical contact is arranged at the end, away from the left fixed frame, of the upper supporting frame, the adjusting handle is provided with a sliding groove, a sliding block is arranged in the sliding groove and connected with a right support, a lower supporting frame is arranged at the top end of the right movable support, and a lower spherical contact is arranged at the end, away from the right movable support, of the lower supporting frame. Through the optical coherence tomography scanner used for diagnosis in the ophthalmology department, the eye fatigue of a patient can be effectively relieved, when seeing a doctor, the diagnosis efficiency for the patient can be guaranteed, the high efficiency of diagnosis is improved, and the comprehensiveness of the diagnosis is guaranteed.