The invention discloses a simplified protocol stack routing and neighbor discovery method applied to a space-ground integrated network, which comprises the following steps: a protocol stack communication address is an identifier with the length of 16 bits, a routing table maintained by a routing subsystem is a three-level hash chain table, and a data packet routing mode is host routing, so that the routing efficiency is further improved. A data packet passes through a routing subsystem to obtain a next-hop node identifier and exit equipment, then the data packet is transmitted to a neighbor subsystem, a corresponding next-hop node Mac address is obtained in the neighbor subsystem according to the next-hop node identifier, maintenance and management are carried out on the neighbor subsystemthrough an identifier neighbor analysis protocol, and the whole network state is monitored. The method effectively solves the main challenges faced by the space-ground integrated network, such as topology dynamic change, node capability limitation, transmission time delay and the like, can improve the security of the backbone network and reduce the bandwidth resource and power consumption of thenetwork, and is suitable for a satellite network environment.