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60 results about "Muscle nerve" patented technology

Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue

Improved assemblies, systems, and methods provide a stimulation system for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination. The stimulation system includes an implantable pulse generator and a lead sized and configured to be implanted subcutaneously in a tissue region. An external controller includes circuitry adapted for wireless telemetry and a charging coil for generating the radio frequency magnetic field to transcutaneously recharge a rechargeable battery in the pulse generator. Using wireless telemetry, the pulse generator is adapted to transmit status information back to the external controller to allow the external controller to automatically adjust up or down the magnitude of the radio frequency magnetic field and / or to instruct a user to reposition the charging coil, the status information adapted to allow optimal recharging of the pulse generator rechargeable battery.
Owner:MEDTRONIC URINARY SOLUTIONS

Implantable pulse generator for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue

Improved assemblies, systems, and methods provide an implantable pulse generator for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination. The implantable pulse generator is sized and configured to be implanted subcutaneously in a tissue region. The implantable pulse generator includes an electrically conductive laser welded titanium case. Control circuitry is located within the case, and includes a primary cell or rechargeable power source, a receive coil for receiving an RF magnetic field to recharge the rechargeable power source, and a microcontroller for control of the implantable pulse generator. Improved assemblies, systems, and methods also provide a stimulation system for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination. The stimulation system provides at least one electrically conductive surface, a lead connected to the electrically conductive surface, and an implantable pulse generator electrically connected to the lead.
Owner:MEDTRONIC URINARY SOLUTIONS

Implantable pulse generator for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue

Improved assemblies, systems, and methods provide an implantable pulse generator for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination. The implantable pulse generator is sized and configured to be implanted subcutaneous a tissue region. The implantable pulse generator includes an electrically conductive case of a laser welded titanium material. Control circuitry is located within the case, the control circuitry including a rechargeable power source, a receive coil for receiving an RF magnetic field to recharge the power source, and a microcontroller for control of the implantable pulse generator. Improved assemblies, systems, and methods also provide a stimulation system for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination. The stimulation system provides at least one electrically conductive surface, a lead connected to the electrically conductive surface, and an implantable pulse generator electrically connected to the lead.
Owner:MEDTRONIC URINARY SOLUTIONS

DNP and DNP Prodrug Treatment of Neuromuscular, Neurodegenerative, Autoimmune, Developmental, Traumatic Brain Injury, Concussion, Dry Eye Disease, Hearing Loss and/or Metabolic Diseases

A composition and method of treatment of neuromuscular, neuromuscular degenerative, neurodegenerative, autoimmune, developmental, traumatic, hearing loss related, and/or metabolic diseases, including spinal muscular atrophy (SMA) syndrome (SMA1, SMA2, SMA3, and SMA4, also called Type I, II, III and IV), traumatic brain injury (TBI), concussion, keratoconjunctivitis sicca (Dry Eye Disease), glaucoma, Sjogren's syndrome, rheumatoid arthritis, post-LASIK surgery, anti-depressants use, Wolfram Syndrome, and Wolcott-Rallison syndrome. The composition is selected from the group consisting of 2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP, bipartite 2,3-dinitrophenol, 2,4-dinitrophenol, 2,5-dinitrophenol, 2,6-dinitrophenol, 3,4-dinitrophenol, or 3,5-dinitrophenol (2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP) prodrugs; Gemini prodrugs, bioprecursor molecules, and combinations thereof. A dose of the composition for treatment of neurodegenerative diseases may be from about 0.01 mg/kg of body weight to about 50 mg/kg of body weight of the patient in need of treatment. A dose of the composition for treatment of metabolic diseases may be from about 1 mg/70 kg of body weight to about 100 mg/70 kg of body weight of the patient in need of treatment, and a maximum dose per day is about 200 mg/70 kg of body weight of the patient in need of treatment.
Owner:MITOCHON PHARMA INC +1

Covalent Small Molecule DCN1 Inhibitors and Therapeutic Methods Using the Same

Small molecule covalent inhibitors of DCN1 and compositions containing the same are disclosed. Methods of using the DCN1 covalent inhibitors in the treatment of diseases and conditions wherein inhibition of DCN1 provides a benefit, like oxidative stress-related diseases and conditions, neurodegenerative diseases and conditions, metabolic disorders, and muscular nerve degeneration, also are disclosed.
Owner:THE RGT OF THE UNIV OF MICHIGAN

Combined correcting and repairing device used after scoliosis operation

InactiveCN111529158AImprove the phenomenon of postoperative nerve damagePromote postoperative repairElectrotherapyMedical devicesSpinal columnPhysical medicine and rehabilitation
The invention discloses a combined correcting and repairing device used after a scoliosis operation. The device comprises a correction unit, a physiotherapy unit and a micro-control unit, the correction unit comprises a correction belt composed of shoulder belts, back belts and a waist belt and a correction instrument which is detachably connected to the correction belt, and the correction instrument comprises a supporting plate, a soft wrapping layer, a telescopic sleeve frame and a miniature electric push rod. According to the invention, an extrusion block matched with spine joint is arranged on the soft wrapping layer, each extrusion block is provided with the miniature electric push rod as a rear support, and precise strength support can be provided for a patient under detection feedback of a flexible pressure sensor. A physiotherapy patch is further provided, not only can be used as a dressing, but also can perform pulse activation on muscle nerves around the back of the patient through a motor column, and can effectively improve the phenomenon that nerves of the patient are damaged after an operation. In conclusion, the correcting and repairing device is convenient to use andgood in supporting and correcting effect, and well helps to perform postoperative nerve repair.
Owner:WEIFANG UNIV OF SCI & TECH

Intraoperative monitoring of neuromuscular function with soft, tissue-mounted wireless devices

The provided systems, methods and devices describe lightweight, wireless tissue monitoring devices that are capable of establishing conformal contact due to the flexibility or bendability of the device. The described systems and devices are useful, for example, for skin-mounted intraoperative monitoring of nerve-muscle activity. The present systems and methods are versatile and may be used for a variety of tissues (e.g. skin, organs, muscles, nerves, etc.) to measure a variety of different parameterps (e.g. electric signals, electric potentials, electromyography, movement, vibration, acoustic signals, response to various stimuli, etc.).
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS +1

DNP and DNP Prodrug Treatment of Neuromuscular, Neurodegenerative, Autoimmune, Developmental, Traumatic Brain Injury, Concussion, Dry Eye Disease, Hearing Loss and/or Metabolic Diseases

A composition and method of treatment of neuromuscular, neuromuscular degenerative, neurodegenerative, autoimmune, developmental, traumatic, hearing loss related, and / or metabolic diseases, including spinal muscular atrophy (SMA) syndrome (SMA1, SMA2, SMA3, and SMA4, also called Type I, II, III and IV), traumatic brain injury (TBI), concussion, keratoconjunctivitis sicca (Dry Eye Disease), glaucoma, Sjogren's syndrome, rheumatoid arthritis, post-LASIK surgery, anti-depressants use, Wolfram Syndrome, and Wolcott-Rallison syndrome. The composition is selected from the group consisting of 2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP, bipartite 2,3-dinitrophenol, 2,4-dinitrophenol, 2,5-dinitrophenol, 2,6-dinitrophenol, 3,4-dinitrophenol, or 3,5-dinitrophenol (2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP) prodrugs; Gemini prodrugs, bioprecursor molecules, and combinations thereof. A dose of the composition for treatment of neurodegenerative diseases may be from about 0.01 mg / kg of body weight to about 50 mg / kg of body weight of the patient in need of treatment. A dose of the composition for treatment of metabolic diseases may be from about 1 mg / 70 kg of body weight to about 100 mg / 70 kg of body weight of the patient in need of treatment, and a maximum dose per day is about 200 mg / 70 kg of body weight of the patient in need of treatment.
Owner:BIOVENTURES LLC +1

Drill bit for total hip replacement minimally invasive surgery

The invention discloses a drill bit for a total hip replacement minimally invasive surgery. A flexible shaft is formed by a spring with certain rigidity and certain flexibility; a handle part and a cutting head are respectively welded on two ends of the flexible shaft; a stainless steel isolation sleeve is arranged in a puncture hole near a surgical incision; the cutting head at the lower end of the flexible shaft is placed in along an inner cavity of the isolation sleeve; a limiting guide sleeve is placed in the surgical incision through an operating handle; the cutting head is driven by theflexible shaft to conduct downward limiting drilling along the limiting guide sleeve; muscle nerves and other important structures of a patient cannot be damaged during high-speed rotation; and the limiting guide sleeve can prevent a drilled hole from entering a pelvic cavity too deep. The cutting head is made of 316L stainless steel, the serious consequence that a drill bit is broken in an acetabular bone and cannot be taken out during bent drilling can be prevented, after drilling is completed, a screw with a proper length is screwed in along an inner cavity of the isolation sleeve through areversible screwdriver, so that an metal part connecting acetabulum can be fixedly, and the drill bit is safe and reliable, and convenient to operate.
Owner:谢军

DNP and DNP prodrug treatment of neuromuscular, neurodegenerative, autoimmune, developmental, traumatic brain injury, concussion, dry eye disease, hearing loss and/or metabolic diseases

A composition and method of treatment of neuromuscular, neuromuscular degenerative, neurodegenerative, autoimmune, developmental, traumatic, hearing loss related, and / or metabolic diseases, including spinal muscular atrophy (SMA) syndrome (SMA1, SMA2, SMA3, and SMA4, also called Type I, II, III and IV), traumatic brain injury (TBI), concussion, keratoconjunctivitis sicca (Dry Eye Disease), glaucoma, Sjogren's syndrome, rheumatoid arthritis, post-LASIK surgery, anti-depressants use, Wolfram Syndrome, and Wolcott-Rallison syndrome. The composition is selected from the group consisting of 2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP, bipartite 2,3-dinitrophenol, 2,4-dinitrophenol, 2,5-dinitrophenol, 2,6-dinitrophenol, 3,4-dinitrophenol, or 3,5-dinitrophenol (2,3-DNP, 2,4-DNP, 2,5-DNP, 2,6-DNP, 3,4-DNP, or 3,5-DNP) prodrugs; Gemini prodrugs, bioprecursor molecules, and combinations thereof. A dose of the composition for treatment of neurodegenerative diseases may be from about 0.01 mg / kg of body weight to about 50 mg / kg of body weight of the patient in need of treatment. A dose of the composition for treatment of metabolic diseases may be from about 1 mg / 70 kg of body weight to about 100 mg / 70 kg of body weight of the patient in need of treatment, and a maximum dose per day is about 200 mg / 70 kg of body weight of the patient in need of treatment.
Owner:MITOCHON PHARMA INC +1

Surface electromyography detecting device applied to spinal rehabilitation system

ActiveCN109288521ARehabilitation is effectiveRecovery safetyOrganic active ingredientsElectrotherapyDiseaseHuman body
Disclosed is a surface electromyography detecting device applied to a spinal rehabilitation system. The spinal rehabilitation system aims at treating muscle slight contracture and muscle tension whichare caused by unhealthy living habits, diseases and the like of modern people. Various drugs which promote bone formation and avoid heterotopic osteogenesis are involved, selectively released in theinterstitial space through special coating layers and enriched in the affected part through the arrangement of a magnetic field. In order to improve the activity of the drugs, a device for forming ganglion interference, an artificial weakly-alkaline environment and the like is additionally arranged. According to the surface electromyography detecting device applied to the spinal rehabilitation system, electricity discharge is evoked through muscle tension-related ganglions of the human body, the muscle and nerve health indexes are effectively improved, and injury healing is promoted; meanwhile, in combination with electromyography detection, self-adaptive adjustment is made in real time to obtain a better therapeutic effect. In the electromagnetic therapy process, in order to seize a better participation time, an instructing device reminds a patient to perform abdominal breathing to cooperate with the magnetic therapy under the management of a control device, and the interference between evoked potentials and normal human electrocardio is avoided.
Owner:NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY

Formula of vagina tightening antibacterial liquid for preventing gynecological diseases and tightening vaginae

The invention discloses a formula of vagina tightening antibacterial liquid for preventing gynecological diseases and tightening vaginae. The formula of the vagina tightening antibacterial liquid comprises the following components in parts by weight: 200-280 parts of traditional Chinese medicine extract, 35-40 parts of growth hormone, 35-40 parts of ICE deep sea mineral crystal ions, 150-160 parts of glycerol, 80-90 parts of perilla oil, 50-60 parts of collagen, 40-50 parts of natural pectin and 650-700 parts of activated water. According to the formula, the traditional Chinese medicine extract, the growth hormone, the ICE deep sea mineral crystal ions, the glycerol, the perilla oil, the collagen, the natural pectin and the activated water are uniformly mixed together through a scientific and reasonable proportion to prepare the vagina tightening antibacterial liquid, and the preparation method is simple; and the vagina tightening antibacterial liquid can stimulate release of pudendum muscle nerve information, improve muscle cell activity, improve the relaxed state of the pudendum and enhance elasticity, so that the vitality of cells in the vagina can be quickly recovered, cell regeneration in the vagina is stimulated, and the inner wall of the vagina is lustrous and elastic.
Owner:郑州世纪亿佰商贸有限公司

A magnetic nanoparticle sphere mixture for spinal rehabilitation system

A magnetic nanoparticle sphere mixture for use in spinal rehabilitation systems. The spinal rehabilitation system treats the slight muscle contracture and muscle tension caused by modern people's bad living habits and diseases. It contains a variety of drugs that promote bone formation and avoid ectopic bone formation. The drugs are selectively released in the tissue gap through a special coating layer and enriched in the affected area through a magnetic field setting. In order to improve the activity of the drug, the present invention also adds devices for forming ganglion interference and artificial weak alkaline environment. The present invention can effectively improve muscle and nerve health indicators and promote injury healing by inducing discharges from ganglia related to muscle tension in the human body; at the same time, self-adaptive adjustments can be made in real time in combination with myoelectric detection to obtain better therapeutic effects. In order to achieve a better cut-in timing in the above electromagnetic therapy process, under the management of the control device, the indicating device prompts the patient to perform abdominal breathing to cooperate with the magnetic therapy, so as to avoid interference between the evoked potential and the normal human ECG.
Owner:NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
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