The invention discloses an energy efficiency optimization method in a single-user MIMO distributed base station system. The energy efficiency optimization method comprises the following steps: firstly, constructing an energy efficiency optimization problem model under a given remote access point set, and transforming the problem model into three sub-problems, namely a rate maximization problem, an energy efficiency optimization problem without rate constraint and a power minimization problem under the rate constraint, for solution, thereby obtaining the optimal solution of a transmission covariance and the maximal energy efficiency; and then orderly bringing access points into an activated access point set in an order from small to large distances between a user and the access points, obtaining the maximal energy efficiency based on the energy rate optimization problem model and determining an access point set finally selected to transmit information to the user. The energy efficiency optimization method in the single-user MIMO distributed base station system is capable of solving the problem of base station transmission pre-coding design in the single-user MIMO distributed base station system and the problem of how to select appropriate distributed access points to maximize the energy efficiency of the system; besides, the energy efficiency optimization method is capable of quickly converging the optimal solution.