The invention discloses a spiral double-rocker guide rod groove cam combination space mechanism for a sliding-plug door, relates to a sliding and plug, sealing, opening and closing mechanism for the sliding-plug door for a vehicle, in particular to the spiral double-rocker guide rod groove cam combination space mechanism for the sliding-plug door of high-speed rail or other railway vehicles. The mechanism comprises a motor, a coupler, a screw, a bearing shaft, a guide rod, a guide rod sleeve, a shaft sleeve, a door carrying rocker, a nut, a short rocker, a door handle, a roller, a roller shaft, a groove cam, a door leaf and a door frame, wherein a spiral mechanism consists of the screw, the nut and the door frame; a double-rocker guide rod mechanism consists of the rocker, the short rocker, the guide rod, the guide rod sleeve, the nut, the bearing shaft, and the shaft sleeve; a groove cam mechanism consists of the bearing shaft, the rocker, the roller, the roller shaft, the groove cam, the door handle, the door leaf and the door frame; the spiral mechanism, the double-rocker guide rod mechanism, and the groove cam mechanism are connected to form the spiral double-rocker guide rod groove cam combination space mechanism; the door frame is fixedly connected with a vehicle body; and the motor which is fixed on the door frame is connected with the screw through the coupler.