62results about How to "Increase blood perfusion" patented technology

Various embodiments provide systems and methods of treating damaged cartilage injuries to joints and connective tissue. Methods and systems useful for permanent relief of pain in joints are also provided herein. Various embodiments provide for combining therapeutic ultrasound energy directed to a joint with a medicant injected into the joint.

A method is provided, including identifying an electrical stimulation protocol as being suitable for augmenting genesis of one or more cell populations in at least one brain region of the subject. The cell genesis is augmented by applying the identified stimulation protocol to an SPG, a greater palatine nerve, a branch of the greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, a lesser deep petrosal nerve, a maxillary nerve, a branch of the maxillary nerve, a nasopalatine nerve, a peripheral site that provides direct or indirect afferent innervation to the SPG, or a peripheral site that is directly or indirectly efferently innervated by the SPG.

A cosmetic treatment method, and a device therefor, are provided that allow for cosmetic treatment of cosmetic disorders, caused by chronological age, environmental factors, changes in physiological functions of skin, such as psoriasis, dermatitis, acne, cellulites, and viral and / or bacteriological attacks. The device comprises a nitric oxide (NO) eluting polymer arranged to contact the area to be cosmetically treated, such that a cosmetic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area. The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said cosmetic dosage of nitric oxide (NO). Furthermore, a manufacturing method for said device is provided.

A physiological sensor apparatus, system and method for determining a physiological characteristic, comprising providing at least one physiological sensor that is adapted to measure at least one physiological characteristic at a target measurement site on a subject's body, heating an extended tissue region on the subject's body, whereby blood perfusion of the tissue region is enhanced, and measuring at least one physiological characteristic at the target measurement site with the physiological sensor during or within a predetermined period after heating the extended tissue region. In one embodiment, the sensor system includes at least one temperature algorithm that is adapted to adjust the heat applied to the extended tissue region based on the body's response to the heat stimuli.

A method of soft tissue treatment of a patient includes placing an applicator onto a surface of the soft tissue, with the applicator including an electrode and a dielectric material vacuum cup. The soft tissue is heated via the electrode. Vacuum is applied to the vacuum cup. The electrode may be at least partially covered by a dielectric material of variable thickness.

A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and / or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end. Lumens extending from the proximal end to each of these distal ends provide for blood circulation within one or between two blood vessels. At least one aperture in one of the lumens positioned near the proximal end provides for active perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment. The inventive catheter may comprise a third lumen positioned entirely within the patient's vasculature, providing passive perfusion of blood to the patient's vasculature downstream of where the third lumen resides in the vasculature when the catheter is inserted into the patient for treatment.

A method of soft tissue treatment of a patient comprises placing an applicator onto a surface of a soft tissue, with the applicator including an RF electrode and a dielectric material having a vacuum cup and a dielectric material under the RF electrode, with the dielectric material under the electrode having an absolute value of difference between polarization factor below center of the RF electrode and below edges of the RF electrode in a range from to 0.10005 mm to 19 800 mm, and heating the soft tissue via the RF electrode, and applying vacuum into a cavity under the applicator with changing pressure value inside the cavity under the applicator compared to pressure in the room during the treatment in range from 0.01 kPa to 100 kPa.

A method is provided that includes identifying that a subject is at risk of suffering from vascular dementia (VaD). Responsively to the identifying, a risk of development of the VaD is reduced by applying electrical stimulation to a site of the subject selected from the group consisting of: a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, and a lesser deep petrosal nerve; and configuring the stimulation to induce at least one neuroprotective occurrence selected from the group consisting of: an increase in cerebral blood flow of the subject, and a release of one or more neuroprotective substances. Other embodiments are also described.

A method is provided that includes identifying that a subject is at risk of suffering from vascular dementia (VaD). Responsively to the identifying, a risk of development of the VaD is reduced by applying electrical stimulation to a site of the subject selected from the group consisting of: a sphenopalatine ganglion (SPG), a greater palatine nerve, a lesser palatine nerve, a sphenopalatine nerve, a communicating branch between a maxillary nerve and an SPG, an otic ganglion, an afferent fiber going into the otic ganglion, an efferent fiber going out of the otic ganglion, an infraorbital nerve, a vidian nerve, a greater superficial petrosal nerve, and a lesser deep petrosal nerve; and configuring the stimulation to induce at least one neuroprotective occurrence selected from the group consisting of: an increase in cerebral blood flow of the subject, and a release of one or more neuroprotective substances. Other embodiments are also described.

A cosmetic treatment method, and a device therefor, are provided that allow for cosmetic treatment of cosmetic disorders, caused by chronological age, environmental factors, changes in physiological functions of skin, such as psoriasis, dermatitis, acne, cellulites, and viral and / or bacteriological attacks. The device comprises a nitric oxide (NO) eluting polymer arranged to contact the area to be cosmetically treated, such that a cosmetic dose of nitric oxide is eluted from said nitric oxide eluting polymer to said area. The nitric oxide (NO) eluting polymer is integrated with a carrier material, such that said carrier material, in use, regulates and controls the elution of said cosmetic dosage of nitric oxide (NO). Furthermore, a manufacturing method for said device is provided.

Disclosed herein are capillary fabrication devices comprising living cells within a support medium. Culture of the cells produces viable lumenized capillary networks with natural or pre-determined geometries and ECM and basement membrane associated with the capillary networks. The capillary networks and the ECM and basement membrane detachable from the capillary networks are useful for tissue engineering applications.

The invention discloses a neck massage device, which comprises a massage device main body and a clamping arm disposed at two ends of the massage device main body, wherein the massage device main bodycomprises a far infrared heat generator, a magnetic therapy part and a massage component. The massage component protrudes from the surface of the massage device main body, and the magnetic therapy part includes a magnet, the infrared light emitted by the far-infrared heater passes through the outside of the massage device main body, the two clamping arms are respectively connected to the two endsof the massage device main body through a connecting mechanism, and the connecting mechanism comprises a connecting plate and a hinge component connected with the massage device main body, the connecting plate is hinged to the hinge component, the connecting plate is foldable by relating to the massage device main body by winding the hinge component, and the clamping arm is relatively slidable along the length of the connecting plate. The neck massage device has the advantages of simple structure, multiple functions and convenient usage.

A method of a soft tissue treatment comprises placing an applicator adjacent to a surface of a body part, the applicator including at least one electrode, providing a fastening mechanism fixing the applicator in contact with the body part, providing a radiofrequency energy by the at least one electrode causing a heating of the soft tissue, providing an electric current to the soft tissue by the at least one electrode causing a muscle contraction, and controlling heating of the soft tissue by the radiofrequency energy and parameters of the electric current provided by the at least one electrode via a control unit, wherein an energy flux density of the radiofrequency energy is in a range of 0.01 mW·mm−2 to 10 W·mm−2 and a frequency of the radiofrequency energy is in a range of 0.1 MHz to 25 GHz, and wherein the body part comprises a face or a chin.

The present invention relates to a device and method for the controlled delivery of a drug to a targeted layer of the skin in a human or animal subject. In particular, the present invention relates to such a device, system and method for selective drug delivery to the cutaneous or subcutaneous layer of skin to enhances the effectiveness of the drug delivery.

The Chinese patent medicine for treating diabetes is an oral medicine prepared with 18 kinds of Chinese medicinal materials, including Adenophora stricta, Radix Puerariae, radix trichosanthis, anemarrhena rhizoma, Rhizoma Coptidis, etc. it has the functions of nourishing Yin, clearing away heat, purging fire-evil, expelling toxic matter, quenching thirst and regulating internal organs owing to the cooperation for the Chinese medicinal materials. The present invention has obvious curative effect and no toxic side effect.

Disclosed herein are systems and methods for preferentially heating subcutaneous tissue. Systems for heating subcutaneous tissue may comprise one or more radio-frequency (RF) electrodes having contoured tissue contacting surfaces, such as electrodes with concave or convex surface contours. Methods may comprise applying RF voltage or current from one or both of the handpieces to attain a target tissue and / or electrode temperature and to maintain the tissue and / or electrode at that temperature.

A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and / or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end. Lumens extending from the proximal end to each of these distal ends provide for blood circulation within one or between two blood vessels. At least one aperture in one of the lumens positioned near the proximal end provides for active perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment. The inventive catheter may comprise a third lumen positioned entirely within the patient's vasculature, providing passive perfusion of blood to the patient's vasculature downstream of where the third lumen resides in the vasculature when the catheter is inserted into the patient for treatment.

The present disclosure relates to a portable radiofrequency (RF) hyperthermia device having flexible applicator treatment electrodes for electric field capacitive coupled energy transfer, the device being useful for increasing the delivery of a systemically delivered drug at a localised target site. The portable RF device is suitable for use by a patient in their own home and the flexible applicator is a flexible, porous, light and easy to manipulate treatment electrode. The inventive device requires no specialist operator to ensure correct usage.

The invention belongs to the technical field of biology and relates to a tumor targeting therapy drug composition, in particular to a cyclooxygenase-2 inhibitor and nano-drug delivery system drug composition and application thereof. According to the drug composition, COX-2 serves as a target spot to comprehensively adjust and control the tumor microenvironment so as to increase nano-drug tumor-interior delivery to be used for tumor therapy. By inhibiting COX-2 of the tumor position, reducing tumor matrix cells, destroying tumor matrix components, facilitating normalization of tumor blood vessels and increasing tumor-interior blood flow pouring and nano-particle tumor-interior penetration, tumor-interior delivery of nano drugs is increased, and the therapy effect of the nano drugs for tumor is improved. The invention provides a novel intervention strategy aiming at the tumor for clinical practice.

An expandable elastic structure is introduced into the left ventricular chamber via intravascular catheter in a retrievable and safe manner, and having let anchors anchored to the layer of mid-myocardium of cardiac wall. The structure helps enhancing blood perfusion in the layer of both subendocardium and mid-myocardium and keeps the volume of both subendocardium and mid-myocardium in an expanded state, as such the expandable elastic structure helps restore cardiac muscular asynchronized contraction manner in a diseased heart of a patient. And eventually the expandable elastic structure prevents progressive remodeling process of a failing heart, and improves cardiac function.

A medical detecting device including at least one miniature probe / lance (hereinafter microprotrusion) containing an integrated sensor which is covered with a protective coating to shield the sensor from fouling and other interactions with a host prior to its desired use is provided. In accordance with the present invention, the protective coating is selectively removed from the sensor prior to using the same. The present invention also provides a method for detecting a selected agent using the medical detecting device of the present invention.

The invention discloses a closed-loop automatic external chest compression control system capable of adaptively adjusting the external chest compression depth. The system comprises an input saturationprocessing module used for carrying out input saturation treatment on signals PETCO2 and Kchest after the band-pass filtering process, wherein the processed signals reflect the blood perfusion degreeand the fracture risk of a current patient, a fuzzy control module used for calculating to obtain a pressing depth adjusting increment according to the processed signals; an output saturation processing module used for carrying out optimization treatment on the pressing depth adjusting increment and outputting the optimized pressing depth adjusting increment; and a fuzzy PID automatic adjustmentmodule used for automatically adjusting the pressing depth of an external chest compression device according to the optimized pressing depth adjusting increment, and carrying out automatic external chest compression according to a target pressing depth value. According to the embodiments of the invention, based on the above design, the physiological status of a patient can be monitored in real time during the automatic external chest compression process. Meanwhile, the external chest compression depth can be automatically adjusted according to the physiological status of the patient. As a result, the safety of external chest compression is improved, and the better blood perfusion effect is achieved.

A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and / or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end. Lumens extending from the proximal end to each of these distal ends provide for blood circulation within one or between two blood vessels. At least one aperture in one of the lumens positioned near the proximal end provides for active perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment. The inventive catheter may comprise a third lumen positioned entirely within the patient's vasculature, providing passive perfusion of blood to the patient's vasculature downstream of where the third lumen resides in the vasculature when the catheter is inserted into the patient for treatment.

The invention discloses a blood circulation assisting device and a control system, and the blood circulation assisting device comprises a sheath tube which is used for being installed in a blood vessel and is provided with a near end and a far end; the first balloon is arranged on the sheathing canal and is positioned in the blood vessel; the pump body is arranged at the far end of the sheathing canal and provided with a blood flow channel, a blood inlet and a blood outlet, the blood inlet and the blood outlet are communicated with the blood flow channel, and the pump body is used for pumping blood in the cardiac chamber into the blood vessel; the controller is arranged at the near end of the sheathing canal, and is configured to control the operation of the pump body and intermittently drive the first balloon to inflate and deflate, so that the first balloon at least partially blocks the blood vessel to cooperate with the pump body to generate pulsatile blood flow. According to the blood circulation auxiliary device and the control system, pulsatile blood flow matched with the heart pulsatile characteristics of the patient can be generated, and heart recovery of the patient is promoted.

The invention discloses a Fumailing capsule for preventing and treating slow arrhythmia and a preparation method of the Fumailing capsule. The capsule is prepared from the following traditional Chinese medicinal materials: 8-12g of ephedra, 8-10g of aconite roots, 2-4g of asarum herb, 25-32g of prepared liquorice roots, 10-14g of radix ginseng, 10-12g of ramulus cinnamomi, 25-32g of prepared rhizome of rehmannia, 8-10g of bretschneider pear pericarp, 10-12g of carthamus tinctorius, 8-10g of fragrant solomonseal rhizome, 10-12g of fossil fragment, 10-14g of curcuma roots, 18-22g of astragalus mongholicus, 26-32g of salvia miltiorrhiza, 8-10g of ginger and 26-30g of Chinese dates. Fumailing particles prepared from the traditional Chinese medicinal materials such as the ephedra, the aconite roots and the asarum herb are used for preventing and treating the slow arrhythmia; the materials are easy to obtain; the preparation method is simple; and the Fumailing capsule has a significant treatment effect on the arrhythmia, takes effect quickly, is safe to use and has no toxic or side effects, and can improve a sinoatrial node function and prevent and treat sinoatrial node hypofunction caused by various reasons.

The present invention is concerned with the use of PDE5 inhibitors in medicine.

The invention relates to the field of reproductive medicine, in particular to a pharmaceutical composition for the treatment of oophoritis which is caused by tuberculosis infection. The pharmaceutical composition for the treatment of oophoritis which is caused by tuberculosis infection includes the components with the following parts by weight: 2 to 3 parts of sanchi and ginseng saponins Rb1, 2 to 4 parts of fructus forsythiae extract, 2 to 4 parts of pink herb extract and 1 to 2 parts of lalang grass rhizome extract. The invention is based on the pharmacological effects of improving blood rheology, expanding blood vessels, improving microcirculation and blood viscosity, regulating immune and so on of the drugs for promoting blood circulation and removing blood stasis, such as sanchi; the invention is combined with the effects of invigorating spleen, replenishing qi, removing stasis, smoothing circulation of blood, anti-inflammation and so on of lalang grass rhizome; the invention makes use of the effects of clearing heat, removing toxicity and better treating non-elimination tuberculosis of fructus forsythiae and the effects of anti-inflammatory and antibacterial of lalang grass rhizome, the pharmacological effects are definite, then the invention can gradually improve the environment of ovarian, the invention is proved that the invention can improve the blood viscosity and blood flow perfusion, so as to increase the weight of ovary, thicken the ovarian wall and narrow the tuberculosis focus, furthermore, the invention can not affect the ovarian functions and be conductive to pregnancy.

A semiconductor laser therapeutic apparatus for irradiating nasal cavity, blood vessel, or acupoints is composed of main body, charging transformer, attached to one side of main body, different charging indication lamps, charging circuitboards, rechargeable batteries, and semiconductor laser coupling head.

The invention provides a pig feed and a processing method thereof and belongs to the technical field of feed formulations and processing. The pig feed is made from soybean meal, wheat bran, cotton seed hull, fish bone meal, a traditional Chinese medicine additive, trace mixture and a probiotic liquid, wherein the traditional Chinese medicine additive is made from Radix Notoginseng, Rhizoma Corydalis, Fructus Crataegi, Cortex Eucommiae, Herba Ephedrae, Ramulus Cinnamomi, Folium Mori and Semen Cassiae; the pig feed is made mainly by fermenting soybean meal, wheat bran and cotton seed hull with probiotics, drying and grinding, and mixing with the traditional Chinese medicine additive, the fish bone meal and trace mixture; through the organic combination of coarse proteins, trace elements, vitamins, probiotics and traditional Chinese medicine, the pig feed can effectively regulate pig intestines and stomach, promote the absorption of nutrients, improve pig immunity, regulate physiology of a pig, regulate the blood glucose and lipid through the blood in the body of the pig, improve myocardial blood oxygen supply and blood perfusion, increase the consumption of fat, reduce the ratio of lean and fat and promote the increase of lean growth rate.