An ergonomic mouse-like cursor control device is disclosed that does not assume any specific posture of hand and fingers. The device provides for freedom of hand's movements rather than supports the hand in a presumably best operative posture. As a result, a human operator can continuously use the inventive cursor control device during a long time without feeling discomfort or accumulating fatigue. In one preferred embodiment, the inventive device is a plate, e.g. of a rectangular form, with a slightly elevated border or rim. For a mouse-type operation of the device, the operator may place onto the plate from one up to all five fingers, while freely flexing, extending, expanding or tightening them at any time. The plate has pressure sensitive zones playing the role of traditional mouse buttons and scrolling wheel. Various other embodiments of the inventive device may differ in shape and in number of components.