The invention relates to a multipurpose intubation fixator and an operation method, and is characterized in that the multipurpose intubation fixator comprises an oral intubation fixator, a nasogastric tube fixator, an open type fixing tube hoop and a head fixing band, the oral intubation fixator comprises an upper lip wing, an upper tooth pad connected with the upper lip wing into a whole, a lower lip wing and a lower tooth pad connected with the lower lip wing into a whole, the upper tooth pad and the lower tooth pad are provided with a cannula cavity and a straw cavity, head fixing belt hooks are arranged on the top faces of the upper lip wing and the lower lip wing, the nasogastric tube fixator is assembled with the oral cannula fixator through nasogastric tube fixator lock holes in the upper lip wing, and the head fixing belt is connected with the head fixing belt hooks on the oral cannula fixator. The fixing device has the advantages that the fixing device can be used for simultaneously fixing the oral intubation and the nasogastric tube, independently fixing the oral intubation, fixing the gastric lavage intubation, assisting in gastroscopy, various patients needing to open the oral cavity and fixing an anaesthetic mask, is reasonable in overall structural design, convenient to use, safe and comfortable, reduces the nursing cost, and improves the success rate of rescue and treatment of the patients.