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2744results about "Test tube stands/holders" patented technology

Disposable vacuum filtration apparatus capable of detecting microorganisms and particulates in liquid samples

A vacuum filtration apparatus (900) for detecting microorganisms and particulates in liquid samples. The apparatus includes a base (901), an absorbent pad (991), a filter (990), a funnel (930), and a lid (960). The funnel is releasably attached to the base, and may contain an integral flexible seal for releasably sealing the filter to the base. The outer wall of the lid may be segmented to make it flexible, this flexibility allows it to be releasably attached to the funnel or the base. The apparatus is designed so that any funnel will fit any base, and any lid will fit any base or any funnel when all parts are manufactured to normal tolerances. The apparatus may be configured to to keep the filter wrinkle free in both the dry and wet states.
Owner:FOXX LIFE SCI

System and method for analyte measurement

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.
Owner:ROCHE DIABETES CARE INC +1

Point of care diagnostic systems

Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate result is desired. The systems and methods process patient data, particularly data from point of care diagnostic tests or assays, including immunoassays, electrocardiograms, X-rays and other such tests, and provide an indication of a medical condition or risk or absence thereof. The systems include an instrument for reading or evaluating the test data and software for converting the data into diagnostic or risk assessment information.
Owner:CYTYC CORP

System and method for determining a temperature during analyte measurement

A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the analyte is determined based upon the corrected DC response. Other methods and devices are disclosed.
Owner:ROCHE DIABETES CARE INC +1

Analyzing cartridge and liquid feed control device

An analyzing cartridge and method for using it to analyze a sample having a plurality of reservoirs and capillaries connected for communication between these reservoirs and is provided therein with a reagent required for analysis. The reservoirs are provided with openings leading to the outside of the cartridge, and the openings are covered with vents each consisting of a gas-permeable / non-liquid-permeable, hydrophobic, porous membrane. The analyzing cartridge requires only trace amounts of a sample and a reagent and no maintenance. It is provided with a non-fluid reagent in vent-carrying reservoirs thereby making it possible to formulate a very trace amount of reagent solution in the cartridge by injecting a reagent dissolving liquid into the reservoirs immediately before analyzing. A liquid feed control device controls the feeding of the liquid between the reservoirs via the capillaries when it is attached to the cartridge to allow or control the entry / exit of air via the vents.
Owner:ASAHI KASEI KK

Synchronization of sample and data collection

A sample collector to collect samples has a chassis with a receptacle that is sized to receive a container, and a restraint positioned about the receptacle to restraint the container in the receptacle. The restraint has an open position that allows a container to be inserted into, or released from, the receptacle, and a locked position in which the container is locked in and cannot be removed from the receptacle. A controller determines a status signal, and in response to the status signal, sends to the restraint, either of (i) an open signal to set the restraint to the open position, (ii) a lock signal to set the restraint to the locked position, or (iii) a stand-by signal to maintain the open or locked position of the restraint.
Owner:SALTER JASON PATRICK

Automated process for isolating and amplifying a target nucleic acid sequence

InactiveUS6890742B2Efficient and high through-put operationEfficient space utilizationBioreactor/fermenter combinationsRotating receptacle mixersIsolation proceduresTemperature control
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
Owner:GEN PROBE INC

Systems and methods for processing samples in a closed container, and related devices

ActiveUS20090298129A1Reduce riskPreventing possible contamination of processing systemProgramme-controlled manipulatorBioreactor/fermenter combinationsBiomedical engineering
A system and method for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the sealed tray. A pipette head and / or other sample manipulation device can be attached to the inside of the barrier, and the barrier can include an interface for a robotic arm or other device. When the barrier is sealed over the tray, the barrier separates the contents of the tray from the robot or other manipulation device. The barrier can be flexible, and allow the robotic arm to move the pipette head throughout the work area of the tray. All samples, reagents, pipette tips and other tools or devices for processing nucleic acid samples may remain within the closed compartment provided by the container during processing.
Owner:COIMMUNE INC

Capped tubes

In a first aspect the present invention provides a screw-capped tube for holding a liquid material therein, the tube having an open mouth at one end only which is adapted to be closed by the screw cap with an inner end of the screw cap extending into the open mouth of the tube, an opposing end of the cap to the inner end of the cap being provided with a circular cylindrical recess extending thereinto and whereof the cylindrical wall of the recess is free of splines, an outer circumferential surface of the cap being provided with a spline whereby the cap is adapted to co-operatively engage with a spline of a tool that will fit on to said opposite end of the cap for rotation of the cap by co-operative engagement of the spline of the tool with the spline of the cap. This arrangement increases versatility and ease in de-capping and re-capping of the tubes. Further aspects also assist with this and / or improve seal efficiency and help to avoid the need for O ring sealing for cryogenic uses and other uses.
Owner:ADVANCED BIOTECHNOLOGIES LTD

Methods and systems for using RFID in biological field

Biological reagent carrier devices and methods are disclosed, which employ RFID techniques to associate information with biological reagents.
Owner:APPL BIOSYSTEMS INC

Modular test tube rack

A modular test tube rack for assembly with similarly constructed racks comprise a flat rectangular body displaying, in a first position, a series of wells extending from its top wall to its bottom wall and adapt to receive tubes therein. A pair of handles vertically extend at opposite end walls of the body, each handle having a lower portion adapted to tightly engage an extension on each end wall and a hand gripping upper portion. The lower portion has a bottom edge configured to anchor with the top edge of the handle of an underposed similarly constructed rack to thereby enable a stacking of two more of these racks. In one embodiment, the body displays a second series of wells extending from the bottom wall to the top wall whereby the body, when in a second position reversed relative to the first position, may also receive test tubes, the handles being reversably mountable to the end wall extension to still enable a stacking of racks in the second position.
Owner:3088081 CANADA

Tube rack

A tube rack comprises a base having an array of vertical openings extending therebetween, the openings being configured and dimensioned to receive a plurality of tubes, with the upper ends of the tubes being accessible at the top surface. The base includes base sidewalls that each include a co-axial trunnion extending from the associated sidewall. The tube rack also includes a rotatable and removable cover having a front wall, a back wall and first and second sidewalls, wherein the first and second side walls each include an associated notch open on a bottom surface thereof to allow the cover to be lowered onto the base, such that each of the notches rests on its associated trunnion and may be (i) vertically raised from its closed position on the trunnions and (ii) rotated about the trunnions from its closed position to allow access to the array of openings, wherein each of the notches includes a trunnion travel surface and a ledge surface and the ledge surface engages its associated trunnion to limit rotation of the cover beyond its full cover position. Each of the openings comprises a plurality of support pads positioned within the opening to vertically support the tube within its associated opening. Each of the pads includes a chamfered concave surface that supportably engages the tube, while providing flow paths through which air may pass through the openings adjacent to the tube.
Owner:MATRIX TECH

Method of using a protective test strip platform for optical meter apparatus

A test strip platform for a testing apparatus of the type using test strips, wherein the platform has a shroud defining a strip track for positioning an inserted strip over an optical aperture for making analytical determinations. The platform has a hood permanently mounted to the shroud for overlying the optical window and protecting the testing apparatus optics. The strip track has stabilizing members for holding the strip in testing position. The hood provides camming members for guiding the leading edge of an inserted strip into cooperative engagement with the stabilizing members for ensuring proper insertion of the strip.
Owner:NIPRO DIAGNOSTICS INC

Automated process for isolating and amplifying a target nucleic acid sequence

InactiveUS20050130198A1Efficient and high through-put operationEfficient comprehensive utilizationRotating receptacle mixersBioreactor/fermenter combinationsIsolation proceduresTemperature control
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
Owner:GEN PROBE INC

Sample analyzer and sample container supplying apparatus

A sample analyzer for analyzing a sample comprising: a sample container receiver capable of receiving either one of a manually supplied sample container and an automatically supplied; a container holder receiver for receiving a container holder holding at least one sample container; a sample container supplier automatically for supplying, to the sample container receiver, a sample container held by the container holder received by the container holder receiver; an aspirator for aspirating a sample within a sample container received by the sample container receiver; and an analyzing part for analyzing the sample aspirated by the aspirator.
Owner:SYSMEX CORP

Self-running sample holder and system having self-running sample holders

A self-running sample holder includes a holder main body, a motor provided in the holder main body, a wheel, a transceiver and a battery. The holder main body has a holder portion which holds a sample with recorded information in an upright state. The wheel is provided in the holder main body and rotated in conjunction with the motor. The motor allows the self-running sample holder to self-run in an upright state. The transceiver is provided in the holder main body. The transceiver outputs a drive signal and drive stop signal to the motor in response to a signal from an external controller. The transceiver exchanges a signal with the controller. The battery is provided in the holder main body. The battery supplies the motor and transceiver with electricity. The battery is chargeable.
Owner:IDS CO LTD

Modular test tube rack

Disclosed herein is a modular test tube rack. The rack contains multiple sub-racks that can be coupled together to form the test tube rack. The sub-rack can be designed to fit into a variety of scientific instrumentation including a fixed rotor centrifuge. The assembled test tube rack can be of a format and size that allows use of standard array pipetters. Thus, a system is provided allowing use of standard array pipetters and high g centrifugation.
Owner:VERTEX PHARMA INC

Automated assay and system

An automated assay processing method including transferring a first number of samples from respective sample containers to a first intermediary vessel, determining the testing adequacy of a second number of samples in a second intermediary vessel, preparing a third number of samples in a third intermediary vessel for downstream testing; and transferring a fourth number of samples from a fourth intermediary vessel to an output sample tray. These steps are all performed essentially simultaneously within the duration of a single clock cycle and are repeated during one or more subsequent clock cycles. The clock cycle may be relative to each intermediary vessel. The clock cycle also may be universal to the first, second, third and fourth intermediary vessels.
Owner:BECTON DICKINSON & CO

Localized temperature control for spatial arrays of reaction media

Individual temperature control in multiple reactions performed simultaneously in a spatial array such as a multi-well plate is achieved by thermoelectric modules with individual control, with each module supplying heat to or drawing heat from a single region within the array, the region containing either a single reaction vessel or a group of reaction vessels.
Owner:BIO RAD LAB INC

Portable thermocycler

This invention relates to a portable thermocycler having a unique geometric configuration, which allows the device to be made durable, compact and adapted for field-use. In general, the device includes a case, a rotary plate having a plurality of constant temperature heating blocks and a plurality of sample wheels, wherein the wheels are rotatable and pivotable to allow a plurality of reaction vessels, organized in cassettes, to be moved into contact with the heating blocks for heat transfer applications.
Owner:UNITED STATES OF AMERICA THE AS REPRESENTED BY THE SEC OF THE ARMY

Diagnostic testing process and apparatus

A method and apparatus for use in a flow through assay process is disclosed. The method is characterised by a “pre-incubation step” in which the sample which is to be analysed, (typically for the presence of a particular protein), and a detection analyte (typically an antibody bound to colloidal gold or a fluorescent tag) which is known to bind to the particular protein may bind together for a desired period of time. This pre incubation step occurs before the mixture of sample and detection analyte come into contact with a capture analyte bound to a membrane. The provision of the pre-incubation step has the effect of both improving the sensitivity of the assay and reducing the volume of sample required for an assay. An apparatus for carrying out the method is disclosed defining a pre-incubation chamber for receiving the sample and detection analyte having a base defined by a membrane and a second membrane to which a capture analyte is bound. In one version the pre-incubation chamber is supported above the second membrane in one position but can be pushed into contact with the membrane carrying the capture analyte thus permitting fluid transfer from the incubation chamber through the capture membrane. In another version the membrane at the base of the incubation chamber is hydrophobic and its underside contacts the capture membrane and when a wetting agent is applied to the contents of the pre-incubation chamber fluid transfer occurs.
Owner:PROTEOME SYST LTD

Disposable test tube rack

InactiveUS20050236346A1Easily allowPrevent tipping and spillingBottle cupboardsKitchen equipmentDual purposeEngineering
A test tube rack for supporting, storing and carrying a plurality of test tubes in a laboratory environment comprising a tray, a central support panel and / or lower support panel and a cover. The tray and cover are identical and interchangeable, and tapered for storage in nested stacks. Wells in the tray bottom are in alignment with corresponding openings in the central support panel and corresponding holes in the lower support panel and with domes in the cover, and serve to locate and retain test tubes within the test tube rack. The cover snap-attaches to the tray by means of at least one molded-in tab on the tray or cover which is received and frictionally retained by a corresponding well on the opposite element, thereby locating and securing the cover to the tray, and also locating and securing the central support panel between the tray and the cover. A dual-purpose support panel has manually removable perforated edges allowing it to serve either as a central support panel or, with the perforated edges removed, as a lower support panel. The test tube rack is preferably made of transparent injection-molded or thermoformed plastic.
Owner:WHITNEY PROD

Apparatus for separating magnetic particles from liquids containing said particles, and an array of vessels suitable for use with such an apparatus

An apparatus for separating magnetic particles from a liquid which contains said particles, said liquid being contained in an elongated vessel (11) having a length axis (12), said vessel being arranged in a vessel holder (13) with its length axis (12) in a substantially vertical position, said vessel (11) having a bottom and a tapered cross-section that diminishes towards the bottom of the vessel and a side wall (14) which has an outer surface which forms an angle with the length axis (12) of said vessel (11). This apparatus comprises a magnet (15) having a plane outer surface (16) and being adapted for being moved by transport means (17) along a motion path (25), said magnet (15) and said transport means (17) being so arranged with respect to said vessel (11) that over a portion of said motion path (25) said plane outer surface (16) of said magnet is in contact with a portion of said outer surface of said side wall (14) of said vessel (11), and transport means (17) for moving said magnet (15) between a first predetermined position and a second predetermined position along said motion path (25).
Owner:ROCHE MOLECULAR SYST INC

Closure appliance for reagent containers

The invention relates to an appliance for opening and closing a reagent-container stopper in a partially or fully automatic analysis apparatus, and to the method, which is applied by means of this appliance, for opening and closing a reagent-container stopper in a partially or fully automatic analysis appliance.
Owner:SIEMENS HEALTHCARE DIAGNOSTICS PRODS

Methods and systems for using RFID in biological field

Biological reagent carrier devices and methods are disclosed, which employ RFID techniques to associate information with biological reagents.
Owner:APPL BIOSYSTEMS INC

Carousel for incubation station

An incubation station has a carousel for receiving a plurality of test sample cards. An even temperature and air flow distribution inside the carousel and incubation of the cards over time at the proper temperature was found to be critically dependent upon air flow characteristics within the incubation station. To optimize air flow, the carousel was given an open rear side that is exposed to an air distribution table having a cover plate placed adjacent to the rear surface of the carousel. The cover plate has a plurality of elongate slots positioned in a symmetrical ring-shaped pattern in registry with the carousel. The elongate slots are positioned at an angle relative to the slots in the carousel such that each carousel slot receives air from more than one slot. An extra fan was also added to the system to increase the flow of air into the air table. Scallop features on the carousel walls also promote even distribution of air flow over the cards. The carousel may be divided into a plurality of carousel segments to increase ease of removal and insertion of the carousel into the incubation station and manufacturability of the carousel.
Owner:BIOMERIEUX INC

Sensor

In order to realize a sensor that is capable of promptly and accurately supplying a small amount of a liquid sample to a filtration part even if the sensor is not held substantially horizontally, this invention provides a sensor having means for supplying a liquid sample to the filtration part by capillary action.
Owner:PANASONIC HEALTHCARE HLDG CO LTD
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